The mediating role of cardiac autonomic imbalance in the association between hypoxic burden and dyslipidemia in obstructive sleep apnea.
BACKGROUND: Obstructive sleep apnea (OSA) is associated with cardiac autonomic dysfunction and impaired lipid homeostasis. We investigated whether cardiac autonomic imbalance mediates the association ...
TEB vs. Swan-Ganz catheter: hemodynamic monitoring agreement in off-pump coronary artery bypass grafting.
OBJECTIVE: To compare the agreement of hemodynamic parameters measured by Swan-Ganz catheter and thoracic electrical bioimpedance (TEB) in patients with coronary heart disease (CHD) undergoing coronar...
Body mass index and dyslipidemia influence responses to anti-PD-1 immunotherapy in colorectal cancer.
BACKGROUND: Obesity is one of the primary risk factors for colorectal cancer (CRC) development, but the impact of obesity on therapeutic responses to anti-programmed cell death protein 1 (PD-1) immun...
J‑shaped link of stress hyperglycaemia ratio with in-hospital and 1-year mortality in hypertension patients: based on the MIMIC-IV database.
BACKGROUND: Stress hyperglycaemia ratio (SHR) is notably linked with unfavourable prognoses. Nevertheless, this correlation in hypertension is elusive. This paper uncovered a link of SHR with mortalit...
The needle-puncture mouse aortocaval AVF model: a state of the art review.
Recent advances using the mouse needle-puncture aortocaval arteriovenous fistula (AVF) model have enhanced our understanding of the complex pathological changes occurring at the juxta-anastomotic area...
Integrative transcriptomic and single-cell analysis identifies anoikis-related molecular signatures in vascular calcification.
BACKGROUND: Vascular calcification (VC) is a life-threatening complication of chronic kidney disease (CKD) driven by vascular smooth muscle cell (VSMC) osteogenic transdifferentiation. Anoikis, a form...
Utility of serum HMGB1 in chronic obstructive pulmonary disease with pulmonary hypertension: A single-centre analysis.
BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) with pulmonary hypertension (PH) worsen outcomes, yet reliable prognostic biomarkers remain lacking. RESEARCH QUESTION...
Blood pressure variability between radial artery and finger is influenced by haemodynamic factors, age and insulin resistance.
BACKGROUND: In clinical practice, blood pressure (BP) is typically assessed using brachial measurements, whereas finger plethysmography is widely used in vascular physiology research. However, agreeme...
Burden of high blood pressure and associated risk for all-cause and cardiovascular mortality among US young adults.
Background: High blood pressure (BP) in young adults is an underrecognised public health issue with potential long-term health consequences, including increased mortality risk. To examine the prevalen...
Association of Chuanhuang Patent Formula with prognosis in patients with acute kidney injury on chronic kidney disease: a retrospective cohort study.
This study evaluated the association of Chuanhuang Patent Formula (CHPF) with short-term renal function parameters and long-term prognosis in patients with acute kidney injury (AKI) on chronic kidney ...
Noninvasive assessment of Doppler-derived estimated fetal interatrial pressure-gradient indices using ductus venosus and pulmonary vein velocities in late-onset fetal growth restriction: a prospective case-control study.
BACKGROUND: Fetal growth restriction (FGR) is associated with progressive hemodynamic deterioration and subclinical cardiac dysfunction. The modified Bernoulli equation applied to ductus venosus and p...
Controversies in the management of fetal growth restriction: a state-of-the-art review.
Fetal growth restriction (FGR) affects 5%-10% of pregnancies and remains a major contributor to stillbirth, neonatal morbidity, and long-term adverse outcomes. Despite its clinical importance, substan...
All-cause healthcare cost differences across ambulatory cardiac monitoring modalities in Medicare beneficiaries: a real-world claims-based study using entropy balancing.
OBJECTIVES: Arrhythmias, including atrial fibrillation and ventricular tachycardia, are associated with substantial morbidity and healthcare utilization in older adults. Ambulatory cardiac monitoring ...
Prevention of new-onset chronic kidney disease with renin-angiotensin system blockers in type 2 diabetes with preserved kidney function.
Renin-angiotensin system (RAS) blockers, including angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), are known to slow chronic kidney disease (CKD) progression...
Association between perioperative D-dimer dynamics and post-treatment localized intravascular coagulation in venous malformations.
OBJECTIVE: To investigate the association between the change in D-dimer levels (ΔD-dimer) and the development of localized intravascular coagulation (LIC) following surgical intervention in patients w...
Hypertensive disorders in pregnancies with early-onset fetal growth restriction: a retrospective cohort study.
OBJECTIVE: Early onset fetal growth restriction (FGR) shares pathophysiologic origins and may precede the development of Hypertensive Disorder of Pregnancy (HDP). The aim of this study was to evaluate...
Early hemodynamic assessment and longitudinal imaging for predicting graft outcomes post-transplant.
BACKGROUND: The early identification of early allograft dysfunction (EAD) and the long-term prediction of graft-related adverse event-free survival (GRAEFS) are crucial for effective post-transplant m...
Hypertension and gut microbial hydrogenases: a comparison of hydrogen metabolism and etiology.
JOURNAL/mgres/04.03/01612956-202612000-00006/figure1/v/2026-07-23T200825Z/r/image-tiff Hypertension is a prevalent chronic condition and serves as a significant risk factor for numerous cardiovascular...
Placental 3D Doppler and uterine artery Doppler for predicting adverse outcomes in placenta accreta: a retrospective cohort study.
BACKGROUND: Placenta accreta spectrum (PAS) poses high maternal morbidity from adverse pregnancy outcomes (APOs), yet uterine artery Doppler has limited predictive value, and the additive role of thre...
Environmental cues signal through circadian control of sarcomeric gene expression during cardiomyocyte hypertrophy.
Environmental disruption alters circadian clock gene expression, increasing the risk of adverse cardiac events and suggesting cardiomyocyte-specific circadian responses to external stimuli. Analyses o...