Differentiation of human induced pluripotent stem cells into cardiac valve cells using 2D and 3D differentiation protocols.
BACKGROUND: Given the high relevance of human cardiac valve disease, recent research aims to differentiate human induced pluripotent stem cells (hiPSCs) into valve endothelial-like cells (VELCs) and, ...
Electroanatomical properties and high-density mapping guided targeted isolation of superior vena cava.
INTRODUCTION: Superior vena cava isolation (SVCI) is associated with complications such as sinus node (SN) and phrenic nerve (PN) injury or SVC stenosis. Our study assessed the electrophysiological pr...
Out-of-pocket costs and catastrophic health expenditure among hospitalised patients with heart failure in northern Tanzania, May-October 2024: a cross-sectional study.
OBJECTIVES: To quantify out-of-pocket (OOP) costs and catastrophic health expenditure (CHE) among patients hospitalised with heart failure (HF) and to identify factors associated with CHE during a sin...
Cryopreservation alters contractile function of human induced pluripotent stem cell-derived cardiomyocytes.
Advanced protocols are available for efficient generation of large quantities of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). Nevertheless, hiPSC-CMs show large batch to bat...
Anatomic variations in basilar artery termination: a systematic review and meta-analysis with presentation of an illustrative case.
PURPOSE: Despite extensive literature on anatomical variations of the basilar artery, evidence on its termination patterns is limited. We sought out to systematically pool the prevalence of basilar ar...
Overcoming barriers to early diagnosis and treatment of p.Val142Ile amyloid transthyretin (ATTR) cardiomyopathy.
The most common hereditary transthyretin (ATTRv) amyloidosis variant in the United States, Val122Ile (p.Val142Ile), is predominantly detected in populations of African ancestry. In this narrative revi...
Migrating Needle in Right Ventricle Wall With Purulent Tamponade.
BACKGROUND Migration of foreign bodies to the right ventricle is a very rare condition, but may lead to a life-threatening state in the patient. Moreover, the presentation of symptoms in such cases ma...
Prognostic value of the TAPSE/PASP-ratio in patients with severe mitral regurgitation undergoing transcatheter edge-to-edge mitral valve repair.
BACKGROUND: Transcatheter edge-to-edge mitral valve repair (M-TEER) represents an effective treatment modality for high-grade mitral valve regurgitation. The right ventricle (RV) to pulmonary artery (...
Documented arteriovenous fistula thrill category and Doppler hemodynamics in mature radiocephalic fistulas: A single-center retrospective study.
ObjectiveTo evaluate the cross-sectional association between routinely documented arteriovenous fistula thrill categories and Doppler hemodynamic parameters in mature radiocephalic fistulas.MethodsThi...
Prognostic characteristics of preoperative serum total bilirubin concentration in myxomatous mitral valve disease in dogs undergoing mitral valve repair.
BACKGROUND: While serum total bilirubin concentration (Tbil) has emerged as a potential prognostic marker in dogs with myxomatous mitral valve disease (MMVD) after mitral valve repair (MVR), its dose-...
The correlation between impaired thyroid hormone sensitivity and 10-year atherosclerotic cardiovascular disease (ASCVD) risk score in patients with type 2 diabetes mellitus.
BackgroundAtherosclerotic cardiovascular disease (ASCVD) is one of the common complications in patients with type 2 diabetes mellitus (T2DM). Thyroid hormones affect cardiovascular function through mu...
Impact of hypertension and antihypertensive medications on early implant failure following sinus augmentation.
BACKGROUND: Hypertension (HTN) is a prevalent condition affecting a significant proportion of the population. It requires careful management due to its potential systemic complications. While the over...
Endodontic status of patients with coronary atherosclerosis: A cross-sectional study.
BACKGROUND: There are no studies in the Colombian population assessing the prevalence and severity of apical lesions (ALs), or the relationship between the frequency and quality of endodontic treatmen...
Coats disease: A narrative review of clinical spectrum, imaging features, and contemporary management.
Coats disease is a rare idiopathic retinal vascular disorder characterized by telangiectatic and aneurysmal retinal vessels, intraretinal and subretinal lipid exudation, and variable progression to ex...
The diagnosis and current treatment of chronic lower extremity arterial disease.
Chronic lower extremity arterial disease (PAD) can be categorized into three subsets: Asymptomatic PAD, Chronic Symptomatic PAD, and Chronic Limb Threatening Ischemia (CLTI). Symptoms, signs and treat...
Dogs evaluated in a home environment show decreased arterial blood pressure and stress levels.
BACKGROUND: Stress may influence blood pressure (BP), making home-based measurements potentially more reliable. HYPOTHESIS/OBJECTIVES: Compare BP, stress, and clinical laboratory results obtained from...
Effect of amiodarone, diltiazem, or both to achieve strict heart rate control in dogs with atrial fibrillation.
BACKGROUND: Dogs with atrial fibrillation (AF) live longer if heart rate is strictly controlled (SHRC, 24-h mean heart rate ≤ 125 beats per minute [bpm]). Amiodarone and diltiazem are used to lower ve...
Visualization of new vessel formation during venous thrombus organization using genetic fate mapping.
BACKGROUND: Endothelial cell (EC) dysfunction contributes to venous thrombosis, and disrupting endothelial angiogenic signaling delays venous thrombus resolution. However, the time course of EC appear...
Blood Pressure Control Among Adherent vs Nonadherent Medicare Patients With Hypertension.
OBJECTIVES: Medication adherence measures for hypertension drive financial incentives and patient care strategies for many value-based health care programs. The association between medication adheren...
Association of Early M2 Pulsatility Index Ratio With Outcomes After Successful Endovascular Thrombectomy.
BACKGROUND AND PURPOSE: We investigated whether early transcranial Doppler (TCD) ultrasound asymmetry indices could serve as bedside predictors of hemorrhagic transformation (HT) and 90-day outcome af...