Cellular Senescence and the SASP in HFpEF: Pathogenic Mechanisms and Therapeutic Targeting.
Heart failure with preserved ejection fraction (HFpEF) represents a complex syndrome strongly associated with aging, characterized by diastolic dysfunction, myocardial stiffness, and chronic low-grade...
Association Between Epicardial Adipose Tissue Thickness and Early Arrhythmia Recurrence After Electrical Cardioversion for Atrial Fibrillation and Atrial Flutter in Patients With and Without Heart Failure-An Observational Study.
Background and Objectives: Atrial fibrillation (AF) and atrial flutter are associated with significant morbidity. While electrical cardioversion (ECV) is a standard treatment for sinus rhythm restorat...
Impact of Individualized Positioning Care on Cardiac Function Recovery and Comfort in Patients After Heart Valve Surgery.
AIM: Postoperative recovery after heart valve surgery is an important topic in the realm of nursing care. This study aimed to evaluate the effect of individualized positioning care on cardiac function...
Age-related changes in METS-IR and HOMA-IR in obese adults and their relationship with cardiometabolic comorbidities.
OBJECTIVE: Insulin resistance (IR) is central to cardiometabolic risk in obesity, but the clinical utility of IR indices may vary by age. We compared homeostasis model assessment for insulin resistanc...
Anti-NMDA receptor encephalitis associated with severe sinoatrial node dysfunction: three case reports and a review of the literature.
OBJECTIVES: To summarize the clinical features and management of severe sinoatrial node dysfunction in anti-N-methyl-D-aspartate (NMDA) receptor encephalitis, and to raise awareness of this rare but l...
Joint Relationship of Cardiovascular-kidney-metabolic Syndrome and Psoriasis with All-cause and Cause-specific Mortality in Adults: A Population-based Analysis.
Psoriasis has been associated with cardiovascular risk, but the combined association of psoriasis and cardiovascular-kidney-metabolic (CKM) syndrome with mortality remains unclear. This study examined...
Towards personalization of 1D blood flow models: sensitivity analysis and parameter calibration.
In this work, we address one of the central challenges in translational computational hemodynamics: how to effectively individualize cardiovascular models in scenarios where patient data are scarce an...
Sex-dependent differences in mitochondrial protein acetylation in metabolic condition, oxidative stress, vascular dysfunction, hypertension, and cardiovascular disease.
One half of adults have hypertension, which is a major risk factor for stroke, myocardial infarction, heart failure, and vascular dementia. There is an urgent need for new therapies, particularly for ...
Circulating MicroRNAs and Clinical Parameters in Hypertrophic Cardiomyopathy: A Systematic Review and Correlation Meta-Analysis.
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is genetically heterogeneous and characterized by left ventricular hypertrophy, myocardial fibrosis, and diverse clinical manifestations. Although circula...
Association between Atherogenic Index of Plasma and Hypertension in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome-A Retrospective Study.
This study aimed to investigate the relationship between the atherogenic index of plasma (AIP) and hypertension in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). A total of 381 OSAHS...
Joint Associations of Multidimensional Socioeconomic Status and Healthy Lifestyle with Prevalent Hypertension: A Large Population-Based Study in Northwest China.
Background/Objectives: The roles of healthy lifestyle and socioeconomic status (SES) in prevalent hypertension, as well as their joint patterns, remain incompletely understood. This study examined the...
Determinants of Adherence to a Ketogenic Diet in Patients with Heart Failure with Reduced Ejection Fraction.
Background: Dietary interventions in heart failure (HF) remain limited, with current guidance focused largely on sodium restriction. Ketone metabolism has emerged as a potential therapeutic target in ...
Circulating microRNAs in Atrial Fibrillation: Clinical Significance and Future Perspectives.
Atrial fibrillation (AF) remains one of the most clinically demanding arrhythmias in contemporary cardiology-not because its mechanisms are unknown, but because what we know does not yet translate int...
Left and Right Heart Remodelling at 1 Year After Transcatheter Versus Surgical Aortic Valve Replacement: A Speckle-Tracking Echocardiography Study.
OBJECTIVES: Speckle-tracking echocardiography (STE) identifies subclinical myocardial dysfunction after aortic valve replacement. We compared strain-based remodelling and prognostic values after trans...
Multidisciplinary management of video-assisted thoracoscopic left cardiac sympathetic denervation in a young child with Jervell and Lange-Nielsen syndrome.
Left cardiac sympathetic denervation (LCSD) via video-assisted thoracoscopy (VATS) is an effective therapy for drug-refractory malignant arrhythmias in congenital long QT syndromes and requires meticu...
Soluble CD146 reflects altered endothelial and metabolic homeostasis in peripheral artery disease.
BACKGROUND: Peripheral Arterial Disease (PAD) is a prevalent but underdiagnosed pathology. Soluble CD146 (sCD146) was described as a marker of endothelial dysfunction and vascular congestion. OBJECTIV...
Menopause age and hypercholesterolemia comorbidities: a region-wide retrospective cohort study in Andalusia, Spain (2016-2022).
OBJECTIVES: To quantify sex- and age-related differences in hypercholesterolaemia diagnosis and associated comorbidities around the menopausal transition, using a population-based real-world dataset. ...
Prevalence and clinical characteristics of sleep apnea in hypertrophic cardiomyopathy: A meta-analysis.
OBJECTIVE: To investigate the prevalence and clinical characteristics of sleep apnea (SA) in patients with hypertrophic cardiomyopathy (HCM). METHODS: Eligible studies were screened and selected from ...
Deep-learning based image reconstruction enables reduced dose CT pulmonary angiography with non-inferior image quality.
To investigate whether a CT pulmonary angiography (CTPA) protocol with reduced radiation dose and deep-learning based image reconstruction (DLIR) is non-inferior in image quality to standard-dose CTPA...
Transpericardial Left Atrial/Left Ventricular Vent Placement During Robotic Mitral Surgery.
Robotic mitral surgery is one of the most common robotic cardiac procedures being performed, which presents many benefits including smaller incisions, less postoperative pain, quicker recovery, decrea...