Pulsed Field Versus Cryoballoon Ablation for Atrial Fibrillation: Procedural Outcomes and Hemolysis-Related Laboratory Changes in a Single-Center Pilot Study.
Background and Objectives: Pulsed field ablation (PFA) and cryoballoon ablation (CRYO) are established approaches for pulmonary vein isolation in atrial fibrillation (AF). Given emerging concerns rega...
Direct oral anticoagulants in elderly patients with atrial fibrillation: a decade-long nationwide retrospective cohort study.
OBJECTIVE: To examine oral anticoagulant (OAC) prescription patterns and clinical outcomes, among elderly patients with atrial fibrillation (AF) during the era of widespread direct oral anticoagulant ...
Decoding the causes of ischemic stroke despite ongoing oral anticoagulation and their clinical impact: the ASPERA-R study.
BACKGROUND: Oral anticoagulants (OACs), including vitamin K antagonists and direct OACs, reduce stroke risk in atrial fibrillation (AF), yet breakthrough ischemic stroke still occurs in 1-2% of patien...
Stroke prevention using oral anticoagulants among patients with atrial fibrillation: a qualitative study of Australian general practitioners.
BACKGROUND: To examine Australian general practitioners' (GPs) perspectives on initiating oral anticoagulation for stroke prevention in patients with atrial fibrillation, and their approaches to monit...
A Deep Learning Framework Based on Denoising and 2D Image Encoding for Arrhythmia Classification.
Electrocardiogram (ECG) signals are essential for arrhythmia detection; however, they are frequently degraded by noise during acquisition, and their evaluation is vulnerable to data-leakage and patien...
Electrical cardioversion for atrial fibrillation: nationwide trends in Denmark, 2010-2022.
BACKGROUND: Electrical cardioversion (ECV) is widely used for restoring sinus rhythm in atrial fibrillation (AF). However, population-level trends in use of ECV in individuals with AF remain poorly ch...
Methadone administration and QT interval prolongation: protocol for a systematic review and meta-analysis.
INTRODUCTION: Methadone is a long-acting opioid used to treat opioid use disorder, cancer pain and provide perioperative analgesia. Methadone administration has been associated with QTc interval prolo...
Extensive spontaneous coronary artery dissection complicated by ventricular tachycardia storm and cardiogenic shock.
A healthy man in his 40s presented with acute anterolateral ST-segment elevation myocardial infarction after sudden-onset chest pain during a coughing episode. Coronary angiography and intravascular u...
Electrical storm after percutaneous coronary intervention for subacute anterior myocardial infarction with heart failure, treated with multidisciplinary therapy.
Electrical storm (ES) following acute coronary syndrome is rare but often fatal. A man in his early 70s experienced syncope and dyspnoea while playing golf, approximately 2 weeks after experiencing ba...
Energy Drinks and Arrhythmias in Adolescents and Young Adults: A Narrative Review of the Last Decade.
Background and Objectives: Energy drinks (EDs), widely consumed by adolescents and young adults, contain caffeine and other stimulants marketed to enhance energy and performance. ED consumption has be...
Endoplasmic Reticulum Stress-Related Immune Signature in Atrial Fibrillation: Machine Learning and Single-Cell Transcriptomics.
This study describes a reproducible computational workflow for identifying endoplasmic reticulum stress (ERS)-related gene signatures in atrial fibrillation (AF) by integrating bulk transcriptomics, m...
Conversational artificial intelligence HeAlth supporT in Atrial Fibrillation Self-Management (CHAT-AF-S): rationale and randomised controlled trial design.
INTRODUCTION: Atrial fibrillation (AF), a common arrhythmia, is associated with impaired quality of life and increased stroke risk and mortality. Clinical guidelines recommend leveraging digital techn...
AI-Based Phenotyping of Atrial Fibrillation Through Generative Topographic Mapping: Prospective Murcia Atrial Fibrillation Project III Cohort Study.
BACKGROUND: The clinical heterogeneity of atrial fibrillation (AF) challenges current classifications and risk scores, limiting their real-world applicability. AI-driven methods may enhance phenotypin...
Peripheral Expression Profiles of Glutathione Reductase and miR-144 in Patients with Atrial Fibrillation.
Background: Atrial fibrillation (AF) is associated with oxidative stress and inflammation. Glutathione reductase (GR) and microRNA-144 (miR-144) may participate in redox-related pathways. This study a...
Population reach and participation rate in opportunistic vs. systematic atrial fibrillation screening: STROKESTOP III.
AIMS: Population-based screening for atrial fibrillation (AF) should be considered in elderly individuals to enable AF detection. However, participation in systematic screening programmes is often sub...
Digital recruitment and prevalence of screen-detected atrial fibrillation in nationwide patch-based ECG screening: the NORSCREEN randomized clinical trial.
AIMS: Conventional screening modalities for atrial fibrillation (AF) are often constrained by considerable resource and logistical demands. The randomized controlled NORwegian atrial fibrillation self...
Workup and management of rhythm disorders in myocarditis and inflammatory cardiomyopathy: a clinical consensus statement of the European Heart Rhythm Association and the Heart Failure Association of the ESC, the ESC Working Group on Myocardial & Pericardial Diseases, the European Association of Preventive Cardiology of the ESC, the Heart Rhythm Society, the Asian Pacific Heart Rhythm Society, and the Latin American Heart Rhythm Society.
Myocarditis is an important and frequently underrecognized cause of atrioventricular conduction disease and ventricular arrhythmias and may also be associated with atrial arrhythmias and sinus node dy...
Stopping Oral Anticoagulation After Catheter Ablation for Atrial Fibrillation in Patients With High Risk of Stroke: STOP-OAC Study.
BACKGROUND: The benefit of continuing oral anticoagulation (OAC) after catheter ablation (CA) for atrial fibrillation (AF) in patients with a high risk of stroke remains unclear. The Safeness or Threa...
Haemolysis and renal effects across pulsed field ablation systems in atrial fibrillation.
AIMS: Pulsed field ablation (PFA) is a non-thermal energy modality for ablation of atrial fibrillation (AF). Although PFA has demonstrated an excellent overall safety profile, increasing evidence sugg...
Left Ventricular Hypertrabeculation and Prognosis in Dilated Cardiomyopathy.
BACKGROUND: Left ventricular (LV) hypertrabeculation, formerly termed LV noncompaction, is a heterogeneous myocardial entity linked to adverse cardiovascular outcomes. This study evaluated embolic ris...