The Effect Modification of Systolic Blood Pressure on the Association of Frailty and Cardiovascular Disease in Community-Dwelling Adults.

Frailty has been increasingly recognized as an important predictor of cardiovascular disease (CVD) risk; however, the modifying role of systolic blood pressure (SBP) in this association remains unclea...

Pituitary Neurolobectomy induces sustained hypotension in male Wistar rats and normalizes blood pressure in male spontaneously hypertensive rats.

Arginine vasopressin is primarily recognized as an osmoregulatory hormone; however, its contribution to vascular tone and blood pressure regulation under basal and hypertensive conditions remains deba...

A Randomized Trial to Investigate the Effects of Low-Dose Colchicine in Patients with Hypertension: Rationale and Design of the COlchicine and HypERtENsion Trial (COHERENT).

Hypertension is a prevalent and significant risk factor for cardiovascular disease (CVD). The immune system and inflammatory response are involved in the pathophysiology of hypertension. We hypothesiz...

Left Ventricular and Left Atrial Mechanics in Resistant Hypertension-The Role of Two-Dimensional Speckle Tracking Echocardiography.

Resistant hypertension (RH) is associated with a high burden of cardiovascular morbidity and mortality. Early detection of subclinical myocardial dysfunction is essential for risk stratification and t...

The Linear Association Between A Body Shape Index and Abdominal Aortic Calcification in Individuals With Hypertension.

OBJECTIVE: This study aimed to evaluate the association between A Body Shape Index (ABSI) and abdominal aortic calcification (AAC) in individuals with hypertension. METHODS: This cross-sectional analy...

Proteins as Mediators of the Association Between Dietary Pattern and Premature Coronary Heart Disease: A Prospective Cohort Study.

The relationship between dietary patterns and premature coronary heart disease (CHD), as well as the underlying proteomic mechanisms, remains incompletely understood. Using data from the Global Burden...

Low-Density Lipoprotein Cholesterol Rebound: Rethinking Appendectomy in Coronary Heart Disease.

Null.

Outcomes of CTO-PCI in the South Asian Population.

This retrospective study evaluated angiographic, procedural, and in-hospital outcomes of chronic total occlusion percutaneous coronary intervention (CTO-PCI) at Aga Khan University Hospital, Karachi, ...

Prognostic Value of HALP and PNI Scores in ICU Patients with Decompensated Heart Failure.

OBJECTIVE: To investigate the association between mortality and nutritional status, assessed using the Haemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score and the Prognostic Nutritional Index ...

Hyperkalemia and its treatment: real-world evidence and managed care considerations supporting use of potassium binders.

An estimated 3.7 million adults in the United States have hyperkalemia. It commonly occurs in patients with chronic kidney disease (CKD) and/or heart failure (HF) and as a result of treatment with ren...

Right Ventricular End-Ejection Pressure Predicts Mortality in Patients With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction.

BACKGROUND: Pulmonary hypertension associated with heart failure with preserved ejection fraction (PH-HFpEF) is a syndrome in which right ventricular (RV) dysfunction influences prognosis. Conventiona...

The Impact of Pre-Transplant Ventricular Assist Device Support on Survival After Heart Transplantation in Pediatric Patients: A Systematic Review and Meta-Analysis of Reconstructed Time-To-Event Data.

OBJECTIVES: Heart transplantation is the gold standard therapy for pediatric end-stage heart failure. Ventricular assist devices (VADs) have improved waitlist survival, but their effect on post-transp...

[Digitalis and Heart Failure].

The current guidelines of the European Society of Cardiology recommend the use of cardiac glycosides/digitalis in patients with heart failure and sinus rhythm only if the LVEF is ≤40% and if heart fai...

Pacritinib Impact on QT Interval: Results of a Thorough QT Study and Post Hoc Analysis of Prospective Clinical Trial Data.

Pacritinib, an inhibitor of JAK2/IRAK1/ACVR1 that is devoid of JAK1 activity, approved for treating myelofibrosis in patients with severe thrombocytopenia, carries a label warning for QT interval prol...

Being Taken Seriously: Patients' Experiences of Participation in Care for Supraventricular Tachycardia-A Phenomenological Study.

AIMS AND OBJECTIVES: For patients with a recurring and elusive heart disorder, participation is challenging because of the need for care across the healthcare system. This paper describes how patients...

[Ventricular tachycardia and left bundle branch block after transcatheter aortic valve implantation: is the valve guilty forever or not?].

New-onset left bundle branch block (LBBB) following transcatheter aortic valve implantation (TAVI) is a common conduction disorder, sometimes transient. Conversely, the development of sustained ventri...

[Cardiac arrest due to fever-induced ventricular fibrillation in a 73-year-old patient with hidden Brugada syndrome: an exceptional case of late onset].

Brugada syndrome is an inherited cardiac channelopathy associated with sudden cardiac death, typically diagnosed in middle-aged individuals. Fever is a well-known trigger for malignant ventricular arr...

[Leadless pacemaker implantation in an adult patient with surgically repaired tetralogy of Fallot].

We report the case of a 47-year-old male patient with a history of tetralogy of Fallot surgically corrected in childhood using the Waterston-Cooley and Cooley techniques. In adulthood, he developed se...

Niacin Ameliorates EHDPHP-Induced Oxidative Stress and Mitochondrial Dysfunction in H9C2 Cells.

2-Ethylhexyl diphenyl phosphate (EHDPHP) is a widely used organophosphorus flame retardant frequently detected in environmental matrices and poses potential health risks. However, its cardiotoxic effe...

Mastoid emissary vein, mastoid emissary foramen, and mastoid emissary canal: anatomy, variability, imaging, and clinical implications.

PURPOSE: The mastoid emissary vein (MEV), mastoid emissary canal (MEC), and mastoid emissary foramen (MEF) are common but variably reported structures of the mastoid-posterior fossa region. Existing l...