The Systemic Immune-Inflammation Index and High-Sensitivity C-Reactive Protein to High-Density Lipoprotein Cholesterol Ratio Predict Moderate and Severe Coronary Artery Stenosis in Older Patients with Coronary Heart Disease.

OBJECTIVE: Coronary heart disease (CHD) stems from functional and organic coronary artery stenosis (CAS). This study explored associations of the systemic immune-inflammation index (SII) and high-sens...

Case Report: Recurrent coronary in-stent restenosis as the primary manifestation of non-criteria antiphospholipid syndrome confirmed by anti-phosphatidylserine/prothrombin IgM antibodies.

BACKGROUND: A 47-year-old female with no traditional CAD risk factors developed recurrent in-stent restenosis (ISR) one year after LAD stenting. She had recurrent pregnancy loss, chronic urticaria, an...

Safety and efficacy of dual-axis rotational vs standard coronary angiography: meta-analysis.

The objective is to compare the safety and efficacy of dual-axis rotational coronary angiography (DARCA) with standard coronary angiography (SA). We performed a systematic review and meta-analysis com...

Data-driven atherosclerotic plaque profiles from QAngio-CT associated with functional impairments assessed with PET-CT.

OBJECTIVE: Although coronary artery disease (CAD) involves progressive atherosclerotic plaque dysfunction, further characterization of different cluster profiles and their impact on myocardial functio...

Correlation between circ_0092576 and Arterial Stenosis Severity and Inflammatory Status in Patients with Coronary Heart Disease and Its Clinical Value.

This study aims to investigate the predictive value of circ_0092576 for coronary heart disease (CHD) and major adverse cardiac events (MACE) risk, and to elucidate its association with the degree of c...

Association between TyG index, TG/HDL-C ratio and coronary heart disease risk in elderly postmenopausal women: a retrospective cohort study.

OBJECTIVE: This study aimed to explore the importance of the triglyceride-glucose (TyG) index and triglyceride (TG)/high-density lipoprotein cholesterol (HDL-C) ratio in predicting the risk of coronar...

Understanding participants' experiences of a behaviour change intervention within cardiac rehabilitation: A nested process evaluation within the STRENGTH randomised controlled trial.

BACKGROUND: The STRENGTH (Self-management and Theory-based Rehabilitation Encouraging New Gateways to Healthy-Hearts) study evaluated a behaviour change intervention embedded within cardiac rehabilita...

Preliminary identification of psychometric cut-off points for the SQoL-CHD: a cross-sectional study based on LPA and ROC analyses in a Chinese clinical sample.

OBJECTIVE: To determine psychometric cut-off points for the male and female versions of the Sexual Quality of Life Questionnaire for Coronary Heart Disease (SQoL-CHD), and to validate their effectiven...

Atherogenic index of plasma and the severity of coronary artery stenosis in patients with type 2 diabetes mellitus: a retrospective cross-sectional study.

OBJECTIVE: This study aimed to examine the relationship between the Atherogenic Index of Plasma (AIP) and the severity of coronary artery stenosis in patients with type 2 diabetes mellitus (T2DM). MET...

Quantifying the metabolic-inflammatory axis: synergistic value of TyG index and FAI in assessing CAD risk among MAFLD patients.

BACKGROUND: This study evaluated coronary inflammation and insulin resistance (IR) using pericoronary fat attenuation index (FAI) and triglyceride-glucose (TyG) index, and assessed their associations ...

Latent profile and associated factors of digital health literacy among patients with coronary heart disease: a cross-sectional study.

OBJECTIVE: This study aims to explore the potential characteristics and associated factors of digital health literacy among patients with coronary heart disease, and to guide targeted intervention mea...

The association between single-point insulin sensitivity estimator and high-sensitivity C-reactive protein with collateral circulation in coronary chronic total occlusion.

BACKGROUND: The single-point insulin sensitivity estimator (SPISE) is a novel metric used to assess insulin resistance. However, its association with collateral circulation impairment in patients with...

Comprehensive Review of Antiplatelet Therapy in Secondary Prevention of Myocardial Infarction: Mechanisms, Clinical Evidence, and Future Directions.

Atherosclerotic cardiovascular disease (ASCVD), particularly myocardial infarction (MI), is the leading cause of mortality and morbidity worldwide. The pathophysiology of MI involves atherosclerotic p...

Development and external validation of an interpretable machine learning model for diagnosing coronary heart disease in patients with type 2 diabetes and MASLD.

INTRODUCTION: Patients with type 2 diabetes mellitus (T2DM) and metabolic dysfunction-associated steatotic liver disease (MASLD) face substantially elevated coronary heart disease (CHD) risk, yet no m...

Subacute Coronary Stent Thrombosis as the Initial Presentation of Acute Myeloid Leukemia: A Case Report and Literature Review.

Subacute stent thrombosis is an uncommon but life-threatening complication of percutaneous coronary intervention (PCI). While mechanical and antiplatelet-related factors are most frequently implicated...

Validating hip- and wrist-ActiGraph accelerometer cut-points for physical activity intensities in people living with coronary heart disease.

People with coronary heart disease (CHD) are encouraged to meet the public health moderate-to-vigorous aerobic physical activity (MVPA) guidelines for secondary prevention of cardiovascular disease. H...

Predictive value of thyroid autoantibodies for coronary heart disease severity in individuals with normal thyroid function based on machine learning and SHAP interpretation.

OBJECTIVE: Assessing the severity of coronary heart disease (CHD) is critical for clinical decision-making. Thyroid autoantibodies are associated with cardiovascular disease, but their ability to pred...

Association between single-point insulin sensitivity estimator and three-vessel coronary disease: a cross-sectional study.

BACKGROUND: The single-point insulin sensitivity estimator (SPISE) is a novel surrogate marker for assessing insulin resistance in humans. Three-vessel coronary disease (TVD) remains a major challenge...

Determining the Physiological Threshold for Angina (ORBITA-FIRE): A Double-Blind, Randomized, Placebo-Controlled Study.

In stable coronary artery disease, the primary goal of percutaneous coronary intervention (PCI) is symptom relief. Fractional flow reserve (FFR) and nonhyperemic pressure ratios such as resting full-c...

From valve prosthesis to coronary artery: a fatal thrombus: a case report.

Coronary embolism is an uncommon cause of acute myocardial infarction, often related to atrial fibrillation or valvular heart disease. In such cases, concomitant valvular thrombosis requires additiona...