Aligning Coronary Stent Trial Enrollment With the U.S. Intended-Use Population: Implications of Site Selection.
Class III cardiovascular device premarket approval (PMA) studies often fail to fully represent the intended-use population (IUP) owing to low enrollment of racial and ethnic minority subjects and wome...
Oxygenation-Sensitive Cardiovascular Magnetic Resonance Imaging to Identify Coronary Microvascular and Vasomotor Dysfunction in Angina and No Obstructive Coronary Artery Disease.
Endothelial-dependent coronary microvascular and vasomotor dysfunction (CMVD), which requires invasive coronary function test (ICFT) with intracoronary acetylcholine for diagnosis, is the predominant ...
Clinical and Economic Outcomes Following First-Time Myocardial Infarction: A Nationwide Cohort Study from the SWEDEHEART Registry.
This study aimed to estimate consequences of myocardial infarction (MI) on long-term outcomes and resource needs by comparing outcomes, healthcare resource use, and associated costs between first-time...
Non-invasive pressure-volume loops by cardiovascular magnetic resonance and outcome in ST-elevation myocardial infarction.
We aimed to investigate if non-invasive pressure-volume (PV) loop variables by cardiovascular magnetic resonance (CMR) are associated with all-cause mortality or heart failure compared to mean arteria...
Gaps in cardiovascular risk identification and preventive therapy before first myocardial infarction.
Diagnostic validation and prognostic implications of serial 0/1/3h stratification in patients with suspected myocardial infarction using high-sensitivity troponin T.
The European Society of Cardiology (ESC) recommends 0/1h-algorithms for triage of patients with suspected myocardial infarction (MI). Recently, cut-offs allowing 3h triage using high-sensitivity cardi...
Focal and Diffuse Coronary Artery Disease Patterns and Placebo-Controlled Angina Relief With Percuatenous Coronary Intervention: ORBITA-2.
Unblinded studies have demonstrated superior procedural and clinical outcomes of percutaneous coronary intervention (PCI) in focal compared with diffuse coronary artery disease. However, data from the...
Splenic Tissue Alterations in ST-Elevation Myocardial Infarction: Determinants and Prognostic Implications.
While previous studies suggest a cardio-splenic axis involving splenic activation and systemic inflammation, presence and clinical significance of splenic tissue alterations on cardiac magnetic resona...
Randomized, Placebo-Controlled Trial of Chronic Total Occlusion Percutaneous Coronary Intervention in Stable Angina: The ORBITA-CTO Trial.
Percutaneous coronary intervention for coronary chronic total occlusion (CTO PCI) is offered for symptom and quality of life improvement, despite the absence of blinded randomized evidence. The aim of...
基于心电图向量的机器学习模型将俯卧位心电图转换为标准心电图的建立与验证
俯卧位心电图在重症监护和特殊检查环境中经常获取，但其解读受到体位变化的显著影响，导致ST段偏移和T波改变，可能干扰STEMI等心血管疾病的诊断。本研究旨在开发一种将俯卧位心电图转换为标准心电图的方法，以方便医师诊断STEMI和其他心血管疾病。前瞻性采集了标准心电图、心电向量图（VCG）和俯卧位心电图数据，建立基于心电图向量的机器学习模型。研究使用多种机器学习算法进行建模，并通过独立数据集进行验证。...