Impact of Diabetes on the Efficacy of Low-Voltage Area Ablation for Persistent Atrial Fibrillation: A Subanalysis of the SUPPRESS-AF Trial.
BACKGROUND: The potential value of low-voltage area (LVA) ablation for persistent atrial fibrillation (AF) has been suggested. However, its efficacy determinants remain unclear. We investigated the im...
Sex Differences in the Effect of Long-Term Blood Pressure Trajectories and Variability on the Atrial Fibrillation Risk in a Korean Cohort.
BACKGROUND: Long-term blood pressure (BP) patterns and variability may influence atrial fibrillation (AF) risk. However, whether these associations differ according to sex is unclear. METHODS: We anal...
Impella 5.5-Assisted Coronary Arterial Bypass Graft in a Patient With Severe Reduced Left Ventricular Function: A Case Report.
Coronary artery disease is the most common type of heart disease. Revascularization with coronary artery bypass grafting can improve survival in patients with severe coronary artery disease and reduce...
A Case of Severe Bradycardia Induced by Mechanical Stimulation of the Nasal Cavity Under General Anesthesia.
The trigeminocardiac reflex (TCR) is clinically defined as the sudden onset of increased parasympathetic activity resulting from stimulation of the trigeminal nerve. This reflex increases parasympathe...
VMP1 forms a Ca(2+) release channel essential for postnatal heartbeat.
Normal heart contraction requires synchronized calcium ion (Ca2+) release from the sarcoplasmic reticulum (SR), traditionally attributed to ryanodine receptor 2 (RyR2). Here, we identify vacuole membr...
Mechanisms of ischaemic strokes and transient ischaemic attacks despite oral anticoagulation in patients with atrial fibrillation.
AIMS: The aim of this article was to characterise the mechanisms underlying "breakthrough" ischaemic stroke (IS) or transient ischaemic attack (TIA) despite oral anticoagulation in patients with atria...
Variation in the use of electrical cardioversion and catheter ablation for atrial fibrillation/flutter according to sex and ethnicity in Aotearoa New Zealand.
AIM: The aim of this article was to examine clinical and demographic factors associated with receipt of rhythm control procedures (electrical cardioversion [ECV] or ablation) in patients with atrial f...
Assessing the risk of drug-induced corrected QT interval prolongation in primary care.
BACKGROUND: Tisdale risk score has been validated for predicting drug-induced QTc prolongation (QTP) in cardiac care. This study aims to determine whether it can guide prescribing and monitoring of QT...
A Cascaded Quantized Spiking Neural Network for Real-Time ECG Arrhythmia Detection on Edge Hardware.
Wearable ECG monitors enable continuous cardiac surveillance, but most still rely on cloud-based analysis with limited on-device support for multi-class arrhythmia detection. Spiking neural networks (...
Experiences of Patients With Atrial Fibrillation Using Technology to Personalize Self-Care Decision-Making: Interpretive Description Study.
BACKGROUND: Atrial fibrillation (AF) is the most common sustained heart rhythm disorder and is a challenging chronic disease to manage. Patients' daily self-care decisions are associated with improved...
Anti-NMDA receptor encephalitis associated with severe sinoatrial node dysfunction: three case reports and a review of the literature.
OBJECTIVES: To summarize the clinical features and management of severe sinoatrial node dysfunction in anti-N-methyl-D-aspartate (NMDA) receptor encephalitis, and to raise awareness of this rare but l...
Circulating microRNAs in Atrial Fibrillation: Clinical Significance and Future Perspectives.
Atrial fibrillation (AF) remains one of the most clinically demanding arrhythmias in contemporary cardiology-not because its mechanisms are unknown, but because what we know does not yet translate int...
Multidisciplinary management of video-assisted thoracoscopic left cardiac sympathetic denervation in a young child with Jervell and Lange-Nielsen syndrome.
Left cardiac sympathetic denervation (LCSD) via video-assisted thoracoscopy (VATS) is an effective therapy for drug-refractory malignant arrhythmias in congenital long QT syndromes and requires meticu...
The early-term effects of the minimally invasive extracorporeal circulation on atrial fibrillation development in patients who underwent coronary artery bypass grafting.
OBJECTIVE: The minimised extracorporeal circulation (MiECC) system is an alternative to the classical extracorporeal circulation (ECC) system in coronary artery bypass grafting (CABG) surgery. Some pu...
Usefulness of serum creatinine-to-albumin ratio for 28-day all-cause mortality in critically ill patients with atrial fibrillation: A retrospective study based on the MIMIC-IV database.
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and is associated with increased short-term mortality in critically ill patients. The creatinine-to-albumin ratio (CAR) is associ...
Noninvasive optogenetic induction of cardiac arrhythmias alters systemic hemodynamics in mice.
Mouse models are valuable for studying the systemic effects of arrhythmia, but traditional methods of heart pacing are invasive and technically complex. Cardiac optogenetics enables precise control of...
Calpain inhibition by calpeptin modulates adipocyte lipid metabolism and secretome-mediated inflammatory crosstalk with hepatocytes.
OBJECTIVE: Calpeptin, a calpain inhibitor with potential for treating inflammatory diseases, reduces extracellular vesicle (EV) secretion. While adipose tissue is a recognized target of calpeptin, its...
Integration of Machine Learning Techniques in ECG-Based Multiclass Arrhythmia Classification with Explainability Analysis.
Electrocardiogram (ECG) analysis is a cornerstone non-invasive diagnostic technique for detecting cardiac arrhythmias, which remain a leading cause of mortality worldwide. While recent advances in dee...
Association between venous access-site closure device use and postoperative nausea and vomiting after atrial fibrillation ablation under propofol sedation: a single-centre retrospective observational study in Okayama, Japan.
OBJECTIVES: To examine whether the use of a venous access-site closure device is associated with the occurrence of postoperative nausea and vomiting (PONV) after atrial fibrillation (AF) ablation unde...
pedQTNet: A Deep Learning Approach to Estimate Corrected QT Intervals from Multi-Lead Conventional ECG Waveforms in Pediatric Patients.
Long QT syndrome (LQTS) is a primary risk factor for ventricular arrhythmias and sudden cardiac death in children. Accurate corrected QT intervals (QTc) measurement is imperative but challenging for n...