Health Status Changes and Long-Term Clinical Outcomes in Patients With Atrial Fibrillation.
IMPORTANCE: Improving health status, including symptoms and quality of life, is a key goal in the management of atrial fibrillation (AF). However, whether improvements in patient-reported health statu...
Bleeding-related quality of life in older adults: Psychometric evaluation of the HEmorrhage Life Impact indeX (HELIX).
BACKGROUND: Older adults treated with anticoagulants for atrial fibrillation (AF) or venous thromboembolism (VTE) face heightened bleeding risk, which can affect physical, emotional and social wellbei...
From Molecules to Machines: An Integrative Framework Linking Molecular Pathogenesis, Multi-Factorial Risk, Risk Stratification, Clinical Management, and Artificial Intelligence in QT Prolongation and Sudden Cardiac Death.
QT prolongation causes torsades de pointes sudden death from heritable, pharmacologic, metabolic, nutritional triggers. Its dimensions have been studied separately. This integrative review synthesizes...
Cost-Effectiveness of Anticoagulation Treatment for Subclinical Device-Detected Atrial Fibrillation.
IMPORTANCE: Anticoagulation for stroke prevention in subclinical, device-detected atrial fibrillation (AF) remains an area of clinical equipoise, and its cost-effectiveness is unknown. OBJECTIVE: To e...
Predictive utility of the baseline Tp-e interval for early arrhythmic events in acute myocardial infarction: A cohort study.
ObjectiveAcute myocardial infarction is a major cause of early cardiovascular morbidity and mortality, with arrhythmias contributing to adverse outcomes. This study evaluated the predictive utility of...
Atrial Fibrillation and Atrial Flutter in Pregnancy: Epidemiology, Pathophysiology, and Management.
IMPORTANCE: The prevalence of atrial fibrillation (AF) and atrial flutter (AFL) among pregnant patients has increased over time, with AF now being the most common sustained cardiac arrhythmia in pregn...
MYO6 and Heart: A Novel Variant in a Deaf Infant With Supraventricular Tachycardia.
BACKGROUND: Variants in MYO6 are well known causes of hereditary deafness and have occasionally been linked to cardiac abnormalities, including hypertrophic cardiomyopathy and prolonged QT interval. H...
Acute Management of Dysrhythmias.
Vascular Interventional Radiologists (VIRs) frequently care for patients with high severity of illness, multiple comorbidities, and physiologic derangements. The incidence and prevalence of abnormal c...
Thyroid storm triggered by immune checkpoint inhibitor therapy.
While immune checkpoint inhibitors (ICIs) have revolutionised cancer treatment, they can cause immune-related adverse events, including thyroid dysfunction and rarely, thyroid storm. Here, we present ...
Increased risk of atrial fibrillation and flutter in patients with Cushing's syndrome: a population-based matched cohort study.
BACKGROUND: Patients with Cushing's syndrome (CS) have a high prevalence of cardiovascular disease, and other recognized risk factors for atrial fibrillation/flutter (AF/AFL); however, the prevalence ...
Prevalence and Characteristics of Cardiac Arrhythmia in Duchenne Muscular Dystrophy: A Retrospective, Single-Center Holter Electrocardiographic Monitoring Study.
BACKGROUND: In Duchenne muscular dystrophy (DMD), cardiac causes account for approximately 30% of all deaths. Therefore, evaluating cardiac function in older patients is important. In addition, curren...
Holter-ECG findings after acute ischemic stroke and TIA: A systematic analysis of the MonDAFIS randomized trial.
Holter-ECG monitoring is a critical component of post-stroke diagnostics, guiding cardiac work-up and secondary stroke prevention. Abnormal ECG findings beyond atrial fibrillation (AF) in stroke patie...
Interventional Management of Atrial Fibrillation in the Chronic Heart Failure Population.
Atrial fibrillation (AF) and heart failure (HF) synergistically interact to exacerbate each other. However, treatment of one entity can greatly improve management of the other. Although historically, ...
Patient-Centered Evaluation of Anticoagulation in Atrial Fibrillation.
BACKGROUND: Prior analyses of trials comparing direct oral anticoagulants (DOACs) to warfarin in atrial fibrillation (AF) have not routinely incorporated patient preferences, despite substantial varia...
[Digitalis and Heart Failure].
The current guidelines of the European Society of Cardiology recommend the use of cardiac glycosides/digitalis in patients with heart failure and sinus rhythm only if the LVEF is ≤40% and if heart fai...
Pacritinib Impact on QT Interval: Results of a Thorough QT Study and Post Hoc Analysis of Prospective Clinical Trial Data.
Pacritinib, an inhibitor of JAK2/IRAK1/ACVR1 that is devoid of JAK1 activity, approved for treating myelofibrosis in patients with severe thrombocytopenia, carries a label warning for QT interval prol...
Being Taken Seriously: Patients' Experiences of Participation in Care for Supraventricular Tachycardia-A Phenomenological Study.
AIMS AND OBJECTIVES: For patients with a recurring and elusive heart disorder, participation is challenging because of the need for care across the healthcare system. This paper describes how patients...
[Ventricular tachycardia and left bundle branch block after transcatheter aortic valve implantation: is the valve guilty forever or not?].
New-onset left bundle branch block (LBBB) following transcatheter aortic valve implantation (TAVI) is a common conduction disorder, sometimes transient. Conversely, the development of sustained ventri...
[Cardiac arrest due to fever-induced ventricular fibrillation in a 73-year-old patient with hidden Brugada syndrome: an exceptional case of late onset].
Brugada syndrome is an inherited cardiac channelopathy associated with sudden cardiac death, typically diagnosed in middle-aged individuals. Fever is a well-known trigger for malignant ventricular arr...
[Leadless pacemaker implantation in an adult patient with surgically repaired tetralogy of Fallot].
We report the case of a 47-year-old male patient with a history of tetralogy of Fallot surgically corrected in childhood using the Waterston-Cooley and Cooley techniques. In adulthood, he developed se...