Cardiovascular diseases remain a global health challenge, with >600 million cases reported annually. Atherosclerosis is a common pathology that underlies various cardiovascular diseases, such as myoca...
Cardiovascular diseases remain a global health challenge, with >600 million cases reported annually. Atherosclerosis is a common pathology that underlies various cardiovascular diseases, such as myoca...
Ferroptosis contributes to myocardial infarction (MI) pathogenesis. However, the role of nuclear receptor subfamily 1 group D member 2 (NR1D2) in MI-associated ferroptosis and its potential interactio...
Cardiovascular diseases (CVDs) remain a leading cause of global mortality, with pathogenesis driven by multifactorial processes including genetic susceptibility, metabolic dysregulation, angiogenesis,...
To compare the effects of single antiplatelet (SAPT), dual antiplatelet (DAPT), and anticoagulation plus antiplatelet (AC + AP) therapies on branch vessel patency and bleeding risk after branched endo...
Evidence regarding sources of heterogeneity in the efficacy of statins for primary prevention of cardiovascular disease (CVD) remains limited. This study aimed to identify trial-level factors contribu...
VIDEO-ASSISTED THORACOSCOPIC RESECTION OF THE LEFT BRACHIOCEPHALIC AND SUPERIOR VENA CAVA FOR PRIMARY AND RECURRENT THYMIC TUMORS.
OBJECTIVE: To evaluate the technical feasibility, safety, and short-term outcomes of video-assisted thoracoscopic surgery (VATS) resections of the left brachiocephalic vein (LBCV) and superior vena ca...
BEYOND CONTRACTILITY: PHENOTYPIC SWITCHING OF VASCULAR SMOOTH MUSCLE CELLS IN ATHEROSCLEROSIS.
Atherosclerosis is a complex and dynamic vascular disease driven by chronic inflammation, lipid accumulation, and profound cellular remodeling within the arterial wall. Among the cellular components o...
A Siemens Single-Shot T1 Mapping Sequence as an Alternative to MOLLI.
BACKGROUND: Native T1 mapping has become an essential tool for quantitative myocardial tissue characterization in cardiac magnetic resonance (CMR). However, widely used techniques such as Modified Loo...
Segmental and global amyloid burden and myocardial mechanics: a multimodality imaging comparison.
Bone scintigraphy with bisphosphonate tracers is a cornerstone of noninvasive diagnosis in transthyretin amyloid cardiomyopathy (ATTR-CM). However, methods for estimating the extent and regional distr...
Coronary Artery Calcium Score, Risk Factors, and Clinical Outcomes in Nonobstructive Coronary Artery Disease: A Long-Term Follow-Up Study.
BACKGROUND: The prognostic value of coronary artery calcium (CAC) score in nonobstructive coronary artery disease (NObCAD; stenosis < 50%) remains insufficiently characterized. OBJECTIVES: To investig...
[Metabolomics and metagenomics reveal mechanism of Xinglou Chengqi Decoction in preventing cerebral ischemia-reperfusion injury].
This study uses a rat model of middle cerebral artery occlusion and reperfusion(MCAO/R) to investigate the mechanism by which Xinglou Chengqi Decoction treats cerebral ischemia-reperfusion injury, emp...
[Heart-brain interaction: mechanisms and therapeutic strategies from integrated TCM and western medicine].
Cardiovascular and cerebrovascular diseases have a high global incidence and are major causes of disability and mortality. This review integrates perspectives from both TCM and modern medicine. Based ...
[Integrating network pharmacology and transcriptomics to reveal mechanism of loganin in ameliorating isoprenaline-induced myocardial injury].
This study employed an integrated strategy combining network pharmacology, transcriptome sequencing, molecular docking, and in vivo and in vitro experimental validation to systematically investigate t...
[Efficacy and mechanism of Xiaoxuming Decoction on neurological function impairment in mice with cerebral ischemia-reperfusion based on metabolomics].
This study aimed to investigate the neuroprotective effects and potential mechanism of Xiaoxuming Decoction(XXM) against cerebral ischemia-reperfusion injury in mice. The middle cerebral artery occlus...
Fibrin Hydrogel Containing Microvascular Fragments for Improving Subcutaneous Islet Transplants in Diabetic Rats.
OBJECTIVES: Subcutaneous tissue serves as a noninvasive and easily accessible site for pancreatic islets transplant; however, poor blood supply impedes survival of pancreatic islet cells and increases...
Assessment of Recipient Renal Transplant Arterial Graft Supply in the Immediate Postoperative Period (≤1 week): A Systematic Review.
OBJECTIVES: Early detection of renal allograft complications can prompt immediate treatment to preserve graft function. Radiological evaluation of allograft vascular supply can be achieved with the us...
Inhalation anesthesia for recording cardiac function in dogs using electrocardiography.
BACKGROUND: Inhalation anesthesia plays a critical role in veterinary cardiology by providing stable conditions for accurate Electrocardiogram (ECG) recordings in dogs. Volatile anesthetics such as se...
Thromboembolic ischemic stroke induces neutrophil recruitment and matrix metalloproteinase-9 release to enhance ischemic brain injury.
BACKGROUND: Although increased levels of neutrophils and matrix metalloproteinase-9 (MMP-9) in the ischemic brain are reported in patients and experimental stroke studies the effects of neutrophils an...