Sex differences in ambulatory blood pressure among patients referred for 24-hour monitoring: A retrospective cross-sectional study.

Few studies have addressed the differences between hypertensive women and men regarding the diagnosis and control of blood pressure (BP). Accordingly, we aimed to assess the possible discrepancies in ...

Biological age acceleration and mortality risk among U.S. adults with cardio-kidney-metabolic syndrome, stages 0-3: An NHANES cohort study.

This study aims to evaluate the associations of Klemera-Doubal Method Biological Age Acceleration (KDM-BAA) and Phenotypic Age Acceleration (PAA) with all-cause and cause-specific mortality in U.S. ad...

Risk factors for sudden cardiac death in heart failure: A systematic review and meta-analysis of risk factors derived from prediction models.

BACKGROUND: Heart failure (HF) is a global health burden with high mortality. Sudden cardiac death (SCD) remains a major complication, highlighting the need for accurate risk prediction. METHODS: We c...

A case report of acute heart failure, pulmonary edema, and pleural effusion in an elderly patient with organic mental disorder: An integrative holistic nursing approach.

RATIONALE: Organic mental disorders complicate acute heart failure (AHF) in elderly patients, creating a heart-brain vicious cycle in which cognitive impairment masks cardiac symptoms while hypoxemia ...

Studies on obesity-related atrial fibrillation in the past 20 years: A bibliometric analysis via CiteSpace and VOSviewer.

BACKGROUND: Obesity is a well-established independent risk factor for atrial fibrillation (AF), and its association has been extensively investigated over the past 2 decades. This bibliometric analysi...

Perforation of the right ventricle and inferior vena cava by bone cement after percutaneous vertebroplasty: A case report.

RATIONALE: Percutaneous vertebroplasty (PVP) is widely used to treat vertebral compression fractures. Although it is generally considered a minimally invasive procedure, leakage and systemic migration...

Rare circle of Willis variants associated with multiple intracranial aneurysms and subarachnoid hemorrhage: A case report.

RATIONALE: Subarachnoid hemorrhage from a ruptured intracranial aneurysm is a type of stroke with high rates of mortality and disability, and the prevalence of aneurysm formation increases in the pres...

Warfarin Dose Adjustment During Rifampicin Therapy: A Case Report with Practical Monitoring Implications.

Warfarin management is challenging because its anticoagulant effect is influenced by drug-drug interactions and individual variability. Rifampicin is a potent inducer of cytochrome P450 enzymes and ca...

Myosin Heavy-Chain-Associated RNA Transcript for Cardiopulmonary Recovery Prediction in High-Intensity Interval Training for Coronary Artery Disease.

This study highlights the expression characteristics of MHRT in CAD and analyzes its predictive potential regarding HIIT intervention on cardiopulmonary function and quality of life in CAD patients. A...

Machine learning-based prediction model for predicting the impact of insulin resistance on the risk of ischemic cardiomyopathy.

BACKGROUND: The triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio and triglyceride glucose-body mass (TyG-BMI) index are reliable indicators of insulin resistance (IR). This study ...

Why guideline-directed medical therapy depends on more than guidelines: microeconomics of medication use in heart failure.

Despite substantial mortality benefits, fewer than 25% of individuals with heart failure with reduced ejection fraction (HFrEF) receive all four pillars of guideline-directed medical therapy (GDMT), w...

Aggressive Sporadic Renal Angiomyolipoma With Tumor Thrombus Extending Into the Inferior Vena Cava, Right Atrium, and Right Ventricle: A Multidisciplinary Case Report.

BACKGROUND Renal angiomyolipoma (AML) is a typically benign mesenchymal tumor with an indolent clinical course. Rarely, AML demonstrate aggressive vascular invasion, most commonly in association with ...

Differential Effects of Cannabidiol and Cannabigerol on Cognition, Neuroinflammation, and Blood-Brain Barrier Integrity in a Rat Model of Iron Overload.

Iron is an essential micronutrient for brain development, participating in mitochondrial respiration, myelination, and neurotransmitter synthesis. However, previous studies have demonstrated that exce...

The interplay between chronobiology, neuroinflammation, and the glymphatic system in neurodegenerative diseases.

Neurodegenerative diseases are traditionally characterized by the progressive accumulation of misfolded proteins and chronic neuroinflammation. However, emerging evidence indicates that the pathogenes...

Three-dimensional tracheal morphologic changes after left pulmonary artery sling repair with and without tracheoplasty.

PURPOSE: In patients with a left pulmonary artery sling (LPAS) and congenital tracheal stenosis, indications for simultaneous slide tracheoplasty remain controversial. This study quantified three-dime...

Endoscopic endonasal transcavernous surgery for knosp grade 3-4 growth hormone-secreting pituitary neuroendocrine tumors: surgical outcomes and predictors of biochemical remission.

Achieving biochemical remission in growth hormone-secreting pituitary neuroendocrine tumors (GH-PitNETs) with cavernous sinus invasion (Knosp grade 3-4) remains a significant surgical challenge. The o...

Genetics-Informed Mapping Identifies a CRIM1-Associated Endocardial Inflammatory Remodeling State in Acute Myocardial Infarction.

BACKGROUND Acute myocardial infarction (AMI) reflects inherited susceptibility and inflammatory remodeling, but the cellular contexts linking genetic risk to disease remain unclear. MATERIAL AND METHO...

Multiterritorial tailored revascularization in adult Moyamoya patients: expanding revascularization approaches to ACA and PCA territories.

Extracranial-intracranial (EC-IC) bypass surgery within the middle cerebral artery (MCA) territory is the gold standard for treating Moyamoya patients once hemodynamic insufficiency is confirmed. Alth...

Bridging the Gap: Harnessing Phytochemical-Loaded Nanocarriers for Enhanced Epilepsy Treatment.

Epilepsy is a chronic neurological disorder characterized by recurrent seizures, posing a significant global public health burden. While conventional anti-seizure medications remain the primary therap...

Metabolic control of smooth muscle cell phenotype switching in atherosclerosis.

The loss of smooth muscle cell (SMC) contractile phenotype contributes to various diseases including atherosclerosis. However, its metabolic basis is not entirely elucidated. Since the transforming gr...