Cardiovascular diseases remain a global health challenge, with >600 million cases reported annually. Atherosclerosis is a common pathology that underlies various cardiovascular diseases, such as myoca...
Cardiovascular diseases remain a global health challenge, with >600 million cases reported annually. Atherosclerosis is a common pathology that underlies various cardiovascular diseases, such as myoca...
Urine sodium concentration and diuretic responsiveness in dogs receiving orally administered loop diuretics for chronic congestive heart failure.
BACKGROUND: Urine sodium concentration (uNa) measures diuretic responsiveness (DR) in acute congestive heart failure (CHF). In humans with chronic CHF receiving loop diuretics PO, low uNa is associate...
Metanephrine-secreting adrenocortical carcinoma in a dog with clinical and biochemical features suggestive of pheochromocytoma.
Metanephrine-secreting adrenocortical carcinoma has been rarely described in humans and, to our knowledge, has not been previously confirmed in dogs. A 12-year-old castrated male Maltese was referred ...
Ferroptosis contributes to myocardial infarction (MI) pathogenesis. However, the role of nuclear receptor subfamily 1 group D member 2 (NR1D2) in MI-associated ferroptosis and its potential interactio...
Pharmacological rhythm control strategy and outcomes in the oldest atrial fibrillation patients: an analysis of the nationwide Italian START registry.
BACKGROUND: Evidence on antiarrhythmic drugs (AADs) in the oldest atrial fibrillation (AF) patients is limited. We investigated clinical characteristics and outcomes associated with AADs use in this p...
Cardiovascular diseases (CVDs) remain a leading cause of global mortality, with pathogenesis driven by multifactorial processes including genetic susceptibility, metabolic dysregulation, angiogenesis,...
To compare the effects of single antiplatelet (SAPT), dual antiplatelet (DAPT), and anticoagulation plus antiplatelet (AC + AP) therapies on branch vessel patency and bleeding risk after branched endo...
Evidence regarding sources of heterogeneity in the efficacy of statins for primary prevention of cardiovascular disease (CVD) remains limited. This study aimed to identify trial-level factors contribu...
QUALITY OF LIFE AMONG YOUNG ADULT PATIENTS WITH CARDIOVASCULAR DISEASE.
BACKGROUND: Cardiovascular diseases (CVD) remain a leading cause of premature mortality and disability globally, including in Kazakhstan. Recently, CVD has shown a concerning trend toward affecting yo...
DETERMINANTS OF DIABETIC FOOT AMONG PATIENTS WITH TYPE 2 DIABETES: A CASE-CONTROL STUDY.
BACKGROUND: Diabetic foot is one of the most serious complications of type 2 diabetes mellitus, often leading to ulcers, infections, and amputations. AIM OF THE STUDY: To assess the risk factors of di...
VIDEO-ASSISTED THORACOSCOPIC RESECTION OF THE LEFT BRACHIOCEPHALIC AND SUPERIOR VENA CAVA FOR PRIMARY AND RECURRENT THYMIC TUMORS.
OBJECTIVE: To evaluate the technical feasibility, safety, and short-term outcomes of video-assisted thoracoscopic surgery (VATS) resections of the left brachiocephalic vein (LBCV) and superior vena ca...
BEYOND CONTRACTILITY: PHENOTYPIC SWITCHING OF VASCULAR SMOOTH MUSCLE CELLS IN ATHEROSCLEROSIS.
Atherosclerosis is a complex and dynamic vascular disease driven by chronic inflammation, lipid accumulation, and profound cellular remodeling within the arterial wall. Among the cellular components o...
A Siemens Single-Shot T1 Mapping Sequence as an Alternative to MOLLI.
BACKGROUND: Native T1 mapping has become an essential tool for quantitative myocardial tissue characterization in cardiac magnetic resonance (CMR). However, widely used techniques such as Modified Loo...
Development of a new device to measure arterial stiffness and its reliability, and its potential to detect history of cardiovascular events in patients with chronic kidney disease.
Atherosclerosis, which leads to cardiovascular disease (CVD), can progress without any symptoms. To prevent CVD, it is important to detect atherosclerotic lesions early and assess their severity. Athe...
A polymorphism in the DOCK7 gene (rs1167998) is associated with salt restriction behavior in hypertensive patients.
Patients with hypertension are recommended to decrease their salt intake. However, some patients do not follow this recommendation. It is possible that some of these individuals cannot restrict their ...
Beyond the CHA2DS2VASc: Hypercoagulable States in Anticoagulated AF Patients.
Despite the proven efficacy of direct oral anticoagulants (DOACs) in preventing thrombus formation in atrial fibrillation (AF), thrombus formation may rarely occur even with appropriate anticoagulatio...
Segmental and global amyloid burden and myocardial mechanics: a multimodality imaging comparison.
Bone scintigraphy with bisphosphonate tracers is a cornerstone of noninvasive diagnosis in transthyretin amyloid cardiomyopathy (ATTR-CM). However, methods for estimating the extent and regional distr...
Artificial Intelligence-Enhanced Electrocardiography Analysis for Diagnosing Chagas Disease.
BACKGROUND: Chagas disease affects millions worldwide and remains a leading cause of cardiomyopathy in Latin America. Early diagnosis remains challenging in endemic regions. Artificial intelligence (A...