Atrial fibrillation (AF) is a common cardiac arrhythmia associated with an increased risk of stroke, heart failure and mortality. While catheter ablation is increasingly used for early rhythm control,...
Atrial fibrillation (AF) is a common cardiac arrhythmia associated with an increased risk of stroke, heart failure and mortality. While catheter ablation is increasingly used for early rhythm control,...
Despite advances in acute care, stroke remains a leading cause of death and long-term disability worldwide, with limited treatment options to improve recovery after stroke. Traditionally, the manageme...
Atherosclerosis, an inflammatory driver of coronary artery disease, manifests as unstable atheromatous plaques and stable fibrous plaques. Although atheromatous plaques have been extensively studied, ...
Cystine: A Key Protective Factor Against Childhood Hypo-HDL Cholesterolemia and Dyslipidemia-A Matched Case-Control Study.
BACKGROUND: Dietary cystine may influence lipid metabolism, but epidemiological evidence in children is limited. This study aimed to investigate the association between dietary cystine intake and dysl...
Ischemic cardiomyopathy remains a major contributor to chronic heart failure despite optimal guideline-directed medical therapy (GDMT). HEAT HF (HBOT and EECP as Adjuvant Therapy in Heart Failure) is ...
Incidence, Clinical Characteristics and Outcomes of Severe Prosthesis-Patient Mismatch in Patients Undergoing TAVI with Large Aortic Annuli.
Background and Objectives: Recent studies have focused on evaluating the hemodynamic results in patients undergoing transcatheter aortic valve implantation (TAVI) with small aortic annuli. There is li...
Outcomes of simplified left atrial appendage occlusion using the WATCHMAN FLX device: the ROSE-FLX study.
AIMS: Conventional left atrial appendage occlusion (LAAO) procedures typically require transoesophageal echocardiography and general anaesthesia, which may limit feasibility in resource-limited settin...
Aortic dissection (AD) is a life-threatening vascular disorder characterized by medial degeneration and phenotypic switching of vascular smooth muscle cells (VSMCs). While integrin subunit alpha 5 (IT...
Early anthracycline cardiotoxicity in adolescents and young adults with sarcoma: a prospective echocardiographic study.
BACKGROUND: Adolescents and young adults (AYAs) with sarcomas often receive high-dose doxorubicin (Dox), but data on early cardiotoxicity in this population are limited. OBJECTIVES: To prospectively e...
Beyond the Maze: Hybrid Ablation and Left Atrial Appendage Occlusion in Cardiac Surgery: Evidence Synthesis and the MESAGE Study Protocol.
Background and Objectives: Atrial fibrillation (AF) is the most common cardiac arrhythmia, present in up to 14-20% of patients undergoing cardiac surgery, with the number of patients expected to doubl...
Impact of concomitant left-sided valve disease on outcomes following tricuspid valve transcatheter edge-to-edge repair: insights from EuroTR.
INTRODUCTION: The impact of coexisting left-sided valvular heart disease (VHD) on clinical outcomes following tricuspid valve edge-to-edge repair (T-TEER) for tricuspid regurgitation (TR) remains uncl...
Arrhythmias in Dengue: A Systematic Review and Meta-Analysis.
BACKGROUND: Cardiac involvement in dengue has been increasingly recognized, yet the true burden and spectrum of arrhythmias remain uncertain due to heterogeneous and fragmented evidence. We conducted ...