Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis.

Heart failure with preserved ejection fraction (HFpEF) is a common cardiovascular disorder characterized by a left ventricular ejection fraction of ≥45%, which is typically accompanied by diastolic dy...

This study aims to investigate left atrial (LA) functional recovery following a TTS episode and assess its association with long-term major adverse cardiovascular events (MACE).

Mixed aortic valve disease (MAVD), combining aortic stenosis (AS) and regurgitation (AR), is prevalent yet understudied at mild-to-moderate severity.

This study investigated the relationship between genetic profiles and clinical, pathological, and surgical outcomes in patients undergoing septal myectomy for obstructive hypertrophic cardiomyopathy (...

Established guidelines recommend consideration for concomitant surgical aortic valve replacement (SAVR) at time of coronary artery bypass grafting (CABG) in patients with moderate aortic stenosis (AS)...

Hemodynamic gain index (HGI) is a novel, simple parameter calculated from resting and peak systolic blood pressure (SBP) and heart rate (HR) during exercise, but its prognostic value in patients with ...

Pharmacologic management after Takotsubo syndrome remains empirical.

Patients with significant aortic regurgitation (AR) not meeting current surgical criteria may develop heart failure with preserved ejection fraction (HFpEF). Left atrial reservoir strain (LASr) reflec...

Microvascular obstruction (MVO) frequently occurs after primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) and can be classified as tr...

In patients with angina despite non-obstructive coronary arteries (ANOCA), coronary vasomotion disorders (CVD) are a common cause for their symptoms. Due to the heterogeneous clinical presentation res...

Left ventricular diastolic dysfunction following Takotsubo syndrome (TS) and ST-elevation myocardial infarction (STEMI) is a marker of impaired myocardial relaxation and reduced ventricular compliance...

Conduction system disturbances resulting in permanent pacemaker implantation (PPI) are common complications after transcatheter aortic valve implantation (TAVI). In some patients, there is delayed rec...

Deep learning prediction of left atrial structure and function from 12-lead electrocardiograms.

Abnormal cardiac atrial structure and function, termed atrial cardiopathy, typically precedes atrial fibrillation and downstream cardiovascular complications, yet detection is limited by the cost and ...

[Clinical characteristics of patients undergoing major orthopaedic surgery in a real-world clinical practice: a physician's perspective].

AIM: To evaluate the prevalence of risk factors in patients undergoing large joint arthroplasty in real-world practice. MATERIALS AND METHODS: Medical history, information about concomitant diseases a...

[Aldosterone: mechanisms of normal and impaired regulation and the possibility of their correction in arterial hypertension. Consensus of Russian Medical Society on Arterial Hypertension (RSH) experts].

In recent years, studies have been carried out that have expanded the understanding of the role of pathophysiological mechanisms underlying impaired regulation of aldosterone and activation of mineral...

[The evolution of the treadmill test in cardiology: from clinical observation to a global standard of functional diagnostics].

The article describes the history of the development and implementation of stress tests in cardiology for the diagnosis of coronary heart disease, with a particular attention to the creation, implemen...

Impact of Internet-Based Pharmacy Care on Patient-Reported Outcomes in Congenital Heart Disease-Associated Pulmonary Hypertension in Yunnan, China.

This study evaluated the effectiveness and cost-effectiveness of Internet-based pharmaceutical care (IPC) incorporating patient-reported outcomes (PROs) in postoperative patients with pulmonary arteri...

Cilioretinal Artery Occlusion Associated with Progressive Optic Nerve Head Ischemic Involvement: A Case Report.

Cilioretinal artery occlusion is an uncommon retinal vascular emergency that can cause acute monocular visual loss, particularly when the macular region is involved. Non-arteritic anterior ischemic op...