Differential Influences of Achieved Blood Pressure on Cardiovascular Outcomes by Left Ventricular Geometries According to Chinese Ethnicity-Specific Echocardiographic Criteria for Hypertensive Patients.

Abnormal LV geometrics implied higher cardiovascular risk for hypertensive patients. Ethnicity-specific cardiographic criteria classified more accurately the left ventricular (LV) geometric patterns f...

Global Sensitivity Analysis for Studies Extending Inferences From a Randomized Trial to a Target Population.

When individuals participating in a randomized trial differ with respect to the distribution of effect modifiers compared with the target population where the trial results will be used, treatment eff...

Opportunistic Assessment of Coronary Artery Calcium Volume and Density From Non-Electrocardiogram-Gated Chest CT Using Artificial Intelligence: Prognostic Implications in a Screening Cohort.

OBJECTIVE: The prognostic value of coronary artery calcium (CAC) volume and density was derived from an automated artificial intelligence (AI)-based analysis of non-electrocardiogram-gated chest CT. M...

Proteins as Mediators of the Association Between Dietary Pattern and Premature Coronary Heart Disease: A Prospective Cohort Study.

The relationship between dietary patterns and premature coronary heart disease (CHD), as well as the underlying proteomic mechanisms, remains incompletely understood. Using data from the Global Burden...

Low-Density Lipoprotein Cholesterol Rebound: Rethinking Appendectomy in Coronary Heart Disease.

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Outcomes of CTO-PCI in the South Asian Population.

This retrospective study evaluated angiographic, procedural, and in-hospital outcomes of chronic total occlusion percutaneous coronary intervention (CTO-PCI) at Aga Khan University Hospital, Karachi, ...

[Wellens syndrome and U-wave inversion during angina].

The authors present a case where the admission ECG showed extensive deep negative U-waves in the precordial leads, in addition to the precordial negative T-waves characteristic of Wellens syndrome. Af...

Association between PRECISE-DAPT score and clinical Outcomes: a subgroup analysis of the DAPT-TR registry.

OBJECTIVE: This study aimed to evaluate whether a PRECISE-DAPT score ≥ 25 identifies a high-risk phenotype associated with adverse ischemic and bleeding outcomes, hospitalisation, and mortality among ...

Red Blood Cell Distribution Width and Stent Length Predict In-Stent Restenosis After Myocardial Infarction: A Retrospective Cohort Study.

This study investigated the predictive value of red blood cell distribution width (RDW) stent length for in-stent restenosis (ISR) drug-eluting stent implantation in patients with acute myocardial inf...

Associations of thyroid hormones with metabolic syndrome and coronary artery stenosis in euthyroid individuals: A cross-sectional study.

This study aimed to investigate the associations between thyroid hormones, metabolic syndrome (MetS), and coronary artery stenosis (CAS) in euthyroid patients, given the insufficient evidence on concu...

Pragmatic trial assessing polygenic risk driven statin therapy for cardiovascular disease prevention: study protocol for the EE-PRS trial.

INTRODUCTION: Atherosclerotic cardiovascular disease (ASCVD) continues to be a leading cause of preventable death globally. Polygenic risk scores (PRS) offer a way to detect individuals at higher rela...

Rentrop collateral grade predicts myocardial viability in chronic total occlusion on cardiac magnetic resonance.

BACKGROUND: Chronic total occlusion (CTO) often triggers collateral coronary development, yet the relationship between angiographically graded collaterals and myocardial viability remains incompletely...

Identification of multi-omic pleiotropy factors for peripheral artery disease.

BACKGROUND: Peripheral artery disease (PAD) is prevalent and frequently co-occurs with type 2 diabetes (T2D) and coronary artery disease (CAD). Although shared genetic factors-pleiotropy-may contribut...

Molecular Basis of Synergistic Causal Effect of Dual GLP-1R and GIPR Agonists for Risk Reduction in Diabetic Retinopathy, Alzheimer Disease, and Coronary Artery Disease in Diabetic Patients.

Background: The dual agonism of glucagon-like peptide-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR) becomes a groundbreaking treatment for type 2 diabetes (T2D) ...

[Chronic coronary syndrome in patients with non-obstructive coronary arteries].

Chronic coronary syndrome is a common cause of chest pain. Ischaemia with non-obstructive coronary arteries (INOCA) is underdiagnosed and more frequent in women. Patients with INOCA have a lower quali...

Development and validation of a machine learning-based model for assessing coronary artery disease risk in postmenopausal women: a dual-center retrospective study.

OBJECTIVES: To investigate the risk factors of coronary heart disease (CHD) and develop a risk assessment model for CHD in postmenopausal women. METHODS: General information, medical history, and labo...

Association of Relative Pericoronary Adipose Tissue Attenuation with Coronary Artery Calcification Severity.

Background and Objectives: Pericoronary adipose tissue (PCAT) attenuation measured on coronary CT angiography is a promising imaging biomarker of coronary inflammation; however, absolute values may be...

Efficacy of using 50 mL syringe manual thrombectomy catheter in patients with heavy thrombus burden undergoing primary percutaneous coronary intervention.

BACKGROUND: Patients with ST-segment elevation myocardial infarction (STEMI) and heavy thrombus burden are at increased risk of distal embolisation and impaired reperfusion during primary percutaneous...

Association of Serum Calprotectin and the C-Reactive Protein-Triglyceride-Glucose Index with SYNTAX Score in Patients with Newly Diagnosed Coronary Artery Disease.

Background and Objectives: Systemic inflammation is a key driver in the progression and complexity of coronary artery disease (CAD). Serum calprotectin and the C-reactive protein-triglyceride-glucose ...

Dual antiplatelet therapy is an effective treatment method after coronary artery endarterectomy: a single-centre retrospective study.

AIM: It was aimed to investigate the patients who underwent coronary artery bypass grafting with coronary endarterectomy (CABG-CE) and postoperative dual antiplatelet therapy (DAPT) in terms of acute ...