Predictive value of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio for in-stent restenosis after drug-eluting stent implantation in patients with coronary heart disease.

BACKGROUND & OBJECTIVE: In-stent restenosis (ISR) remains a major obstacle after drug-eluting stent (DES) implantation in patients with coronary heart disease (CHD), in which dyslipidemia play importa...

Comparative Performance of Calcium-Modification Strategies for Coronary Lesions: A Network Meta-Analysis of Randomized Trials.

INTRODUCTION AND OBJECTIVES: Calcified coronary lesions are associated with an increased risk of percutaneous coronary intervention (PCI) failure. Despite the availability of several calcium-modificat...

Red blood cell distribution width is associated with coronary artery disease in latent tuberculosis infection: a machine learning-based study.

BACKGROUND: Latent tuberculosis infection (LTBI) is associated with an increased risk of coronary artery disease (CAD), potentially mediated by systemic inflammation. Traditional lipid-based risk mode...

Geriatric syndromes and intrinsic capacity in older adults with coronary heart disease: a cross-sectional study in China.

BACKGROUND: Geriatric syndromes (GS) are highly prevalent among community-dwelling older adults with self-reported physician-diagnosed coronary heart disease (CHD), but their association with intrinsi...

Uncovering Potential Druggable Targets in Coronary Atherosclerosis: A Proteome-Wide Mendelian Randomization Study With Cross-Platform and Experimental Validation.

BACKGROUND: Coronary atherosclerosis (CA) is a leading cause of cardiovascular morbidity and mortality worldwide. This study is aimed at identifying candidate plasma proteins and potential therapeutic...

Molecular basis of coronary artery disease-malignancy comorbidity: inflammation, immunometabolism, thrombosis, and cardio-oncology translation.

Coronary artery disease (CAD) and malignancy frequently coexist in aging populations and share multiple risk factors, including smoking, obesity, diabetes, dyslipidemia, chronic inflammation, and meta...

AI-assisted segmentation-based fusion model integrating deep learning, radiomics, and clinical parameters for identifying coronary heart disease risk in patients with MAFLD.

BACKGROUND/OBJECTIVES: Metabolic dysfunction-associated fatty liver disease (MAFLD) is associated with an increased risk of coronary heart disease (CHD), which is one of the leading causes of chronic ...

Impact of prehospital triggers, time of onset, and symptom-to-door time on the prognosis of patients with coronary heart disease.

OBJECTIVE: This study aims to conduct a prehospital registry study on coronary heart disease (CHD) to investigate the effects of prehospital triggers, time of onset, and symptom-to-door time (S2D) on ...

Lack of association between Triglyceride glucose-body mass index and glomerular filtration rate in patients with coronary heart disease after percutaneous coronary intervention: a retrospective case-control study.

BACKGROUND: There exists a close and complex bidirectional relationship between cardiovascular disease (CVD) and chronic kidney disease (CKD). CVD is a well-established risk factor for CKD, while the ...

Regulatory T cells in cardiac allograft vasculopathy: from mechanistic insights to clinical tolerance.

Cardiac allograft vasculopathy (CAV) is the primary impairment that influences the long-term prognosis of transplanted hearts. CAV is characterized by diffuse intimal hyperplasia of the coronary arter...

HALP Score as a Novel Marker Associated with Coronary Collateral Circulation in Patients with Chronic Total Occlusion.

BACKGROUND: Coronary collateral circulation (CCC) is a key determinant of myocardial viability and prognosis in patients with chronic total occlusion (CTO). The hemoglobin, albumin, lymphocyte, and pl...

Global research trends and hotspots evolution in type 2 diabetes mellitus complicated with coronary heart disease: a bibliometric analysis from 2016 to 2026.

BACKGROUND: The comorbidity burden of type 2 diabetes mellitus complicated with coronary heart disease is steadily increasing. However, there is a lack of systematic mapping of the research landscape,...

Age-Stratified Prognostic Comparison of Three Chronotropic Incompetence Definitions in Patients with Suspected Coronary Artery Disease Undergoing Exercise Stress SPECT-MPI.

BACKGROUND: Chronotropic incompetence (CI) is an exercise-derived marker of impaired heart rate response with prognostic relevance in myocardial perfusion imaging, but its interpretation may vary by d...

Association between stress hyperglycemia ratio and acute total occlusion in patients with non-ST-segment elevation myocardial infarction.

BACKGROUND: Acute total occlusion (ATO) of the culprit artery identifies a high-risk subgroup of patients with non-ST-segment elevation myocardial infarction (NSTEMI), but its early recognition remain...

Triglyceride-glucose index is associated with the severity of coronary artery disease.

Cardiovascular disease(CVD) remains a leading cause of mortality worldwide. Among CVDs, coronary heart disease (CHD) is the most prevalent and represents the primary contributor to chronic disease-rel...

[Intracavitary thrombus as a differential diagnosis of intramyocardial dissection].

We present the case of a 47-year-old man with ischemic cardiomyopathy and a previous extensive acute myocardial infarction (AMI), who had undergone multiple percutaneous coronary interventions and pro...

Association of Composite Metabolic Indices and Oxidative Stress Biomarkers with Coronary Atherosclerosis Detected by CT Angiography in Premenopausal Women with Metabolic Syndrome.

BACKGROUND: Metabolic syndrome (MetS) is increasingly prevalent among premenopausal women and is associated with a higher risk of subclinical atherosclerosis. This study investigated whether composite...

Association of C-reactive protein-albumin-lymphocyte index and coronary artery calcification on major adverse cardiovascular events of dialysis patients with acute coronary syndrome.

BACKGROUND AND OBJECTIVE: Inflammation, immune dysfunction, malnutrition and severe coronary artery calcification (CAC) are critical cardiovascular risk factors in patients on dialysis. However, their...

Thyroid hormone sensitivity, insulin resistance and visceral fat area as determinants of prevalent coronary heart disease in euthyroid patients with type 2 diabetes.

BACKGROUND: Coronary heart disease (CHD) remains a leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Whether thyroid hormone sensitivity indices add value for ...

Association between gallstones and subclinical coronary atherosclerosis: An observational study with propensity score matching.

Previous studies reporting an association between gallstones and coronary artery disease have not considered the types of coronary artery plaque. Additionally, the association between gallstones and s...