Atrial fibrillation in patients with alcohol-associated hepatitis leads to increased mortality.
BACKGROUND: Alcohol consumption is associated with increased risk for development of atrial fibrillation. Outcomes of patients with atrial fibrillation in the context of acute alcohol-associated hepat...
Comparative effects of sacubitril/valsartan versus enalapril on QRS duration and cardiac function in heart failure patients undergoing left bundle branch area pacing.
BACKGROUND: Left bundle branch area pacing (LBBaP) has emerged as a physiological pacing strategy for cardiac resynchronization therapy in patients with heart failure (HF) and left bundle branch block...
Genetic ancestry and risk of atrial fibrillation in individuals of Black ethnicity in the UK Biobank.
BACKGROUND: Black individuals have a lower incidence of atrial fibrillation (AF) than White individuals, despite a higher burden of traditional risk factors. Prior studies have suggested that European...
Safe cochlear implantation in a child with Wolff-Parkinson-White syndrome.
Wolff-Parkinson-White (WPW) syndrome is a congenital cardiac conduction abnormality. It is characterised by ventricular pre-excitation that arises from abnormal electrical conduction through an access...
A meta-analysis of randomized controlled trials on atenolol's impact on postoperative atrial fibrillation in adults undergoing cardiac surgery.
Prior research has conducted a limited number of studies on the efficacy of atenolol in preventing atrial fibrillation following cardiac surgery (CS). Consequently, a comprehensive evaluation and meta...
Target-centered network pharmacology and molecular docking reveal potential mechanisms and bioactive compounds of Zhigancao Decoction in insomnia-Arrhythmia comorbidity.
This study aimed to investigate the potential mechanisms of Zhigancao Decoction (ZGCT) in insomnia-arrhythmia comorbidity using a target-centered network pharmacology and molecular docking approach. I...
Patterns and trends of mortality in patients with arrhythmia and cerebrovascular disease in the United States: a nationwide analysis of older adults.
Arrhythmias and cerebrovascular disease commonly coexist in older adults and are associated with increased mortality risk. However, population-level trends and demographic disparities in related death...
A Complex Arrhythmic Phenotype in a Pediatric Patient with Variants in SCN5A and KCNH2.
Long QT Syndrome type 2 (LQT2) and Brugada syndrome are inherited cardiac channelopathies that predispose affected individuals to ventricular arrhythmias and sudden cardiac death. We report the case o...
Coronary Artery Embolism From Atrial Flutter Presenting as Cardiac Arrest and ST-Elevation Myocardial Infarction: Diagnostic and Therapeutic Challenges.
BACKGROUND Coronary artery embolism (CAE) is an infrequent but clinically significant non-atherosclerotic cause of ST-elevation myocardial infarction (STEMI). It presents unique diagnostic and therape...
Diffuse hemispheric glioma, H3 G34-mutant, in Simpson-Golabi-Behmel syndrome: the first reported case.
Simpson-Golabi-Behmel syndrome (SGBS) is an overgrowth syndrome associated with an increased risk of certain malignancies; however, gliomas have not previously been reported in patients with SGBS. Los...
Classification models for KCNQ1 variants distinguish functional and trafficking effects to enhance pathogenicity interpretation.
Missense variants in the potassium channel KCNQ1 underlie most cases of congenital long QT syndrome (LQTS), one of the most common genetic arrhythmias. Variants affect protein stability, trafficking, ...
The Association Between Matrix Metalloproteinase-1, -2, -3, -9, and -12 Gene Polymorphisms and Atrial Fibrillation.
Atrial fibrillation (AF) is a prevalent cardiac arrhythmia associated with significant morbidity and mortality. Structural remodeling of the left atrium, particularly myocardial fibrosis, plays a key ...
Investigation and management of breakthrough ischemic stroke in anticoagulated patients with atrial fibrillation.
Ischemic stroke is a serious complication of atrial fibrillation that is associated with substantial morbidity and mortality. For patients with non-valvular atrial fibrillation, treatment with a direc...
Validity, reliability and clinical utility of the Glittre ADL test in patients with atrial fibrillation.
Identification of Pyroptosis-Related Gene Signatures Associated with Predicted Immune-Cell Enrichment in Atrial Fibrillation.
Background: Research demonstrates that pyroptosis is a critical factor in the progression of cardiovascular diseases and their related complications. Nevertheless, the precise association between this...
How to Safely Anticoagulate Patients With Renal Impairment.
Chronic kidney disease (CKD), a highly prevalent condition worldwide, is associated with increased thrombotic and bleeding risks. Thrombotic risks include heightened cardiovascular risk and that of ve...
Ablation outcomes in PVC-induced cardiomyopathy: A systematic review and meta-analysis stratified by site of origin.
BACKGROUND: Frequent premature ventricular complexes (PVC) can lead to a reversible form of left ventricular (LV) dysfunction termed PVC-induced cardiomyopathy (PIC). Catheter ablation is increasingly...
Role of antazoline in cardioversion of atrial fibrillation: A PRISMA-compliant systematic review and meta-analysis.
BACKGROUND: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. Antazoline, a first-generation antihistamine with antiarrhythmic properties, has shown efficacy in the rapid conve...
Expression patterns of pyroptosis-related genes in atrial fibrillation and their application in diagnostic models.
Atrial fibrillation (AF) is a common cardiac arrhythmia associated with substantial morbidity and mortality worldwide. However, its underlying mechanisms are still not completely understood. Emerging ...
R-R Interval Histogram-Based Deep Learning for 3-Class Atrial Fibrillation Screening in Garment-Type Wearable Holter Electrocardiogram Monitoring: Algorithm Development and Validation Study.
BACKGROUND: Long-term garment-type wearable Holter electrocardiographic (ECG) monitoring is frequently affected by noise contamination, which complicates automated atrial fibrillation (AF) detection i...