Periprocedural Mortality Risk After Elective Atrial Fibrillation Ablation in Japan.
IMPORTANCE: Evidence on the safety of atrial fibrillation ablation during rapid growth in both procedural volume and the number of hospitals performing it remains inconsistent. Although clinical regis...
Validation of a deep learning-based system for sleep staging, arousal detection, and respiratory event scoring in atrial fibrillation patients.
PURPOSE: Obstructive sleep apnea is a common yet underdiagnosed sleep disorder in patients with atrial fibrillation (AF). Although polysomnography (PSG) is the gold standard, its costs and complexity ...
Antithrombotic strategy according to age in patients with atrial fibrillation and drug-eluting stents: a post hoc analysis of the ADAPT AF-DES randomised trial.
BACKGROUND: Evidence for non-vitamin K antagonist oral anticoagulant (NOAC) monotherapy for older patients with atrial fibrillation (AF) and drug-eluting stents is lacking. OBJECTIVES: We aimed to eva...
Hypertrophic Cardiomyopathy and the Risk of Bradyarrhythmia and Permanent Pacemaker Implantation: A Nationwide Cohort Study.
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is associated with various arrhythmias, including bradyarrhythmia. The relationship between HCM and bradyarrhythmia, and subsequent need for permanent pac...
Temporal Trends in Multimorbidity Patterns in Patients With Atrial Fibrillation-A Nationwide Cohort Study.
BACKGROUND: The prevalence of both atrial fibrillation (AF) and multimorbidity is increasing with population aging. However, reliable and comprehensive data on temporal trends in multimorbidity among ...
Risk factors for carfilzomib-related cardiovascular adverse events in Chinese patients with multiple myeloma: A real-world retrospective cohort study.
BackgroundAlthough an association between carfilzomib and cardiovascular adverse events has been well documented, the risk factors for carfilzomib-induced cardiovascular adverse events in the Chinese ...
Ventricular arrhythmogenesis in pulmonary hypertension: From right ventricular remodeling to clinical implications.
Pulmonary hypertension (PH) results in chronic pressure overload of the right ventricle, leading to progressive structural, metabolic, neurohumoral, and electrophysiological remodeling. Although right...
Temporal Trends in Mortality Due to Ischemic Heart Disease and Cardiac Arrhythmias in the United States From 1999 to 2023.
BACKGROUND: Ischemic heart disease (IHD) remains a leading cause of mortality in the United States, while arrhythmia-related deaths are increasing. However, long-term mortality trends involving both c...
Association of the NOS1AP rs10494366 Genetic Variant With Drug-Induced QT Prolongation.
Drug-induced QTc prolongation (diQTP) is a major risk factor for torsades de pointes and sudden cardiac death. This study evaluated whether carriers of the G allele of the NOS1AP rs10494366 T > G vari...
Real-time GPU-accelerated coupled cardiac system: Integrating bidirectional interactions between living optogenetic monolayers and computational simulations.
OBJECTIVE: Reentrant arrhythmias are life-threatening cardiac events that are difficult to study due to limited experimental control over the complex circuit dynamics. We present a real-time coupled c...
Effectiveness of Continuous Levalbuterol Versus Albuterol During a National Shortage: A Retrospective Observational Cohort Study.
INTRODUCTION: Bronchospasm requiring continuous inhaled albuterol is a common reason for pediatric intensive care unit (PICU) admission. Albuterol's racemic composition may contribute to adverse effec...
From Electrical Morphology to Physiological Dynamics: Lessons From ECG Adoption for the Clinical Integration of Heart Rate Variability.
BACKGROUND: Heart rate variability (HRV) has remained a relatively finite and niche tool in cardiology despite decades of research supporting its physiological and clinical relevance. This limited ado...
Assessing perceived social support in atrial fibrillation: Development and validation of an instrument to inform nursing care development.
BACKGROUND: Atrial fibrillation (AF) is associated with a significant clinical and psychosocial burden. It requires adequate informational, emotional, and functional support in addition to evidence-ba...
Comparative Cardiovascular Safety and Exploratory Bleeding Outcomes of Ibrutinib, Acalabrutinib, and Zanubrutinib in Mantle Cell Lymphoma: A Propensity Score-Matched Real-World Analysis.
BACKGROUND: Bruton tyrosine kinase inhibitors are central to the treatment of relapsed or refractory mantle cell lymphoma, but cardiovascular and bleeding toxicities influence treatment selection. Ibr...
[Management of oral anticoagulant therapy after catheter ablation of atrial fibrillation].
In recent years, catheter ablation for atrial fibrillation (AF), particularly pulmonary vein isolation, has become an increasingly used and evidence-based treatment aimed primarily at improving sympto...
Four-Chamber Deformation Remodeling and Atrial Fibrillation After Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy.
INTRODUCTION: Septal myectomy treats hypertrophic obstructive cardiomyopathy (HOCM), but its effect on myocardial deformation across cardiac chambers is incompletely defined. We evaluated chamber-spec...
National Trends & Disparities in Ischemic Heart Disease & Cardiac Arrhythmias Related Mortality in the United States From 1999 to 2024: A CDC Wonder Analysis.
BACKGROUND: Ischemic heart disease and cardiac arrhythmias are major contributors to cardiovascular mortality in the United States. Understanding long-term national trends and demographic disparities ...
Pharmacological Insights and Clinical Challenges of Wenxin Keli in Arrhythmia Treatment.
Cardiac arrhythmias remain a leading cause of cardiovascular morbidity and mortality worldwide. Although conventional antiarrhythmic drugs are effective, their use is constrained by proarrhythmic risk...
Evaluation of the effect of Healing Touch on coronary artery bypass grafting recovery: A randomized controlled trial.
BACKGROUND: Healing Touch (HT) is used to provide holistic care, improve outcomes, and provide comfort. However, there is minimal published literature on its effects among inpatients undergoing corona...
AI-quantified Myosteatosis at CAC CT for Prediction of Atrial Fibrillation and Heart Failure: The Multi-Ethnic Study of Atherosclerosis.
Purpose To evaluate whether the artificial intelligence (AI)-quantified mean thoracic skeletal muscle (TSM) attenuation from coronary artery calcium (CAC) scans predicts incident cardiovascular diseas...