Case analysis of tachycardia-induced cardiomyopathy secondary to persistent tachycardia in children.

Tachycardia-induced cardiomyopathy secondary to persistent tachycardia in children is a distinct form of cardiomyopathy caused by sustained or frequent tachyarrhythmias. It is characterized by cardiac...

Single Cell RNA Sequencing Reveals THBS1+CD14+ Monocyte Modulates Inflammatory Activation via NRLP3-Inflammasome in Congenital Heart Block.

Isolated congenital heart block (iCHB) is defined as atrioventricular block without structural cardiac defects, characterized by irreversible fibrosis of the cardiac conduction system. Maternal autoan...

Network and Pairwise Meta-Analysis of the Association Between Novel Hypoglycemic Agents and Atrial Fibrillation Risk in Patients With Type 2 Diabetes Mellitus.

OBJECTIVE: To evaluate the atrial fibrillation (AF) risk of sodium-glucose cotransporter-2 inhibitors (SGLT-2i), glucagonlike peptide-1 receptor agonists (GLP-1RA) and dipeptidyl peptidase-4 inhibitor...

Diagnosis-to-Ablation Time and Atrial Arrhythmia Recurrence After Ablation.

IMPORTANCE: Diagnosis-to-ablation time (DAT) has emerged as a potential predictor of ablation outcomes in atrial fibrillation (AF). Limited evidence is available on the association of prolonged DAT, a...

Effectiveness of Nurse-Led atrial Fibrillation Detection for Patients With Embolic Stroke of Unknown Source in Stroke Units: A Retrospective Study.

BACKGROUND: Atrial fibrillation is a primary cause of ischemic stroke, necessitating early detection, particularly in patients with embolic stroke of undetermined source. While nurseled continuous ele...

Hospitalization for Malignant Arrhythmias Following Initiation of Donepezil: A Retrospective Cohort Study.

PURPOSE: Limited evidence suggests donepezil might pose an increased risk of malignant arrhythmias. We examined whether donepezil initiation was associated with a higher risk of hospitalization for ma...

The Barthel Index in Predicting Response to Cardiac Resynchronization Therapy and Clinical Outcomes in Patients With Heart Failure.

BACKGROUND: Cardiac resynchronization therapy (CRT) response in heart failure (HF) patients is multifactorial, with limited data on its association with activities of daily living assessed by the Bart...

A 67-Year-Old Woman With Intractable Cough and Dyspnea After Catheter Ablation for Atrial Fibrillation.

A 67-year-old woman with diabetes mellitus, hypertension, and atrial fibrillation, but no smoking history, sought treatment for chronic cough, dyspnea, and intermittent expectoration of small, thread-...

Strauss-Defined LBBB Identifies Patients With Improved Outcomes After CRT-D: A Comparative Cohort Study.

BACKGROUND: Left bundle branch block (LBBB) is a well-established predictor of response to cardiac resynchronization therapy (CRT) in heart failure with reduced ejection fraction. However, several ele...

How to Replace the TQT Study-The Use of Concentration-QTc Modeling to Exclude a Small Effect of a Novel Drug on QT Interval: Historical Perspective and Implementation.

The initial ICH E14 guidance described the thorough QT/QTc (TQT) study with the purpose of evaluating whether a new drug has effects on the QTc interval. Following its adoption, concentration-QTc (C-Q...

Dexmedetomidine for the prevention of postoperative atrial fibrillation: A systematic review and meta-analysis.

ObjectivePostoperative atrial fibrillation, a prevalent complication following cardiac surgery, significantly increases patient morbidity and healthcare expenditures. Although dexmedetomidine has been...

Intracardiac Echocardiography Versus Transesophageal Echocardiography for Guidance of Atrial Fibrillation Ablation: A Systematic Review and Meta-Analysis of Procedural Safety and Efficacy.

PURPOSE: Transesophageal echocardiography (TEE) is the standard periprocedural imaging modality for atrial fibrillation (AF) catheter ablation but carries the burden of esophageal instrumentation, fre...

Effect of the ligament of Marshall excision during minimally invasive cardiac surgery-coronary artery bypass grafting (MICS-CABG) on the prevention of postoperative new-onset atrial fibrillation (LOMEX-AF): study protocol for a randomised controlled trial.

INTRODUCTION: Postoperative atrial fibrillation (POAF) remains one of the most common complications following coronary artery bypass grafting (CABG), including minimally invasive cardiac surgery-CABG ...

An Unusual Etiology of Bayés' Syndrome: Fabry Disease.

We present the case of a 72-year-old female with Fabry disease who developed an advanced interatrial conduction block and atrial fibrillation, a condition known as Bayés' syndrome. Fabry disease is an...

Atrial Fibrillation and Lipid-related Indices in Japanese Men: An Age-matched Case-control Study.

BACKGROUND/AIM: Atrial fibrillation (AF) is associated with cardiovascular risk factors. Although certain lipid-related indices, including the ratio of low-density lipoprotein (LDL) cholesterol to hig...

Prognostic Significance of Right Bundle-Branch Block Associated with Acute ST Elevation Myocardial Infarction.

Right bundle-branch block (RBBB) during acute ST elevation. Known about how RBBB influences the prognosis of acute STEMI in the background of changing demography. The main objective of the study was t...

Electrocardiographic Repolarization Changes Following Orchiectomy: Insights Into QT Interval Prolongation and Clinical Implications.

INTRODUCTION: Sex steroid hormones influence ventricular repolarization and QT interval duration. Testosterone has been associated with shorter QT intervals, whereas androgen deprivation may prolong r...

Idiopathic thoracic aortic aneurysm in a dog with 2:1 atrioventricular block.

A 14-year-old castrated male spitz dog was presented with intermittent coughing. Physical examination revealed bradycardia and a grade 3/6 left apical systolic murmur. Thoracic radiographs demonstrate...

[Ranolazine: established indications and emerging therapeutic potential].

Ranolazine, approved for the symptomatic treatment of chronic stable angina, is currently indicated as an additional treatment when angina symptoms are not controlled with traditional drugs such as be...

[The application of artificial intelligence in arrhythmology].

In recent decades, clinical practice has been founded on the principles of evidence-based medicine, where therapeutic decisions arise from the integration of clinical expertise, patient preferences, a...