Transcatheter pulmonary valve replacement: what we know, what we still want to know.
PURPOSE OF REVIEW: Transcatheter pulmonary valve replacement (TPVR) has transformed the management of patients with congenital heart disease (CHD) with dysfunctional pulmonary outflow tracts. Technolo...
Pouch-like infective endocarditis of the mitral valve.
A cell atlas of the developing human outflow tract of the heart and its adult aortic valve derivatives.
The outflow tract (OFT) of the heart carries blood away from the heart into the great arteries. During embryogenesis, the OFT divides to form the aorta and pulmonary trunk, creating the double circula...
BenchTop Validation of UNICORN Leaflet Modification Technique in Redo-Transcatheter Aortic Valve Replacement.
BACKGROUND: Coronary obstruction is a critical risk in valve-in-valve transcatheter aortic valve replacement (TAVR). The UNICORN (undermining iatrogenic coronary obstruction with radiofrequency needle...
Modification of Calcified Native and Surgical Bioprosthetic Aortic Valves: Lessons From the Bench.
BACKGROUND: Leaflet modification (LM) techniques, including electrosurgical and mechanical BASILICA (bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary artery...
Balloon-Assisted Translocation of the Mitral Anterior Leaflet to Prevent Outflow Tract Obstruction During TMVR: The BATMAN Registry.
BACKGROUND: BATMAN (balloon-assisted translocation of the mitral anterior leaflet) is an increasingly adopted technique to modify the anterior mitral leaflet (AML) and prevent left ventricular outflow...
The ELASTA-T Technique for TTVR After Failed T-TEER: An Operator-Oriented Guide to Planning, Execution, Pitfalls.
Failure of tricuspid transcatheter edge-to-edge repair (T-TEER) with persistent severe tricuspid regurgitation (TR) is an increasingly encountered clinical scenario in contemporary structural heart di...
Leaflet Modification Technique With UNICORN in Failed Aortic Bioprosthesis: Procedural Step-by-Step, Best Practice, and Troubleshooting.
The UNICORN (undermining iatrogenic coronary obstruction with radiofrequency needle) technique was developed in 2022 to reduce the risk for coronary obstruction during valve-in-valve transcatheter aor...
Mitral Valve Leaflet Modification: A Working Group Position Statement on Best Practices and Step-by-Step Guide.
Left ventricular outflow tract (LVOT) obstruction is a potentially lethal complication of transcatheter mitral valve replacement (TMVR). The risk for LVOT obstruction can reliably be identified on pre...
Sex Differences in Clinical Outcomes and Loss of Life Expectancy After Aortic Valve Surgery for Infective Endocarditis: A SWEDEHEART Study.
BACKGROUND: Female patients with infective endocarditis (IE) are referred to surgery less often than male patients, and research on sex differences after IE surgery is inconclusive. Understanding the ...
Outcomes of intraprocedural haemodynamic changes in patients undergoing mitral transcatheter edge-to-edge repair.
BACKGROUND: While the mean left atrial pressure (mLAP) reduction during mitral transcatheter edge-to-edge repair (M-TEER) has been suggested as a potential prognostic marker, comprehensive evidence fr...
Temporal trends in mitral edge-to-edge repair for primary mitral regurgitation.
BACKGROUND: The evolving landscape of mitral valve transcatheter edge-to-edge repair (M-TEER) for mitral regurgitation (MR) has seen continuous advancements, driving improvements in therapeutic effica...
Quantification of mitral regurgitation: from traditional methods to artificial intelligence.
Mitral regurgitation (MR) is a common valvular disorder and associated with adverse outcomes. Echocardiography is the primary imaging modality for MR assessment; however, standard methods rely on geom...
Disease-Associated Remodeling of m6A RNA Methylation in Human Interstitial Cells From Fibro-Calcific Aortic Valves.
Calcific aortic valve disease is common in older adults and a major cause of aortic stenosis. Despite its clinical impact, there are still no effective drugs that slow disease progression, and treatme...
"⅓ Yacoub" for correction of supravalvular aortic stenosis: valve-sparing root enlargement and ascending aorta replacement in an adult patient.
Congenital supravalvular aortic stenosis is a rare form of left ventricular outflow-tract obstruction, which is frequently associated with genetic disorders such as Williams-Beuren syndrome, despite s...
Minimally invasive pulmonary valve replacement via left anterior mini-thoracotomy after Tetralogy of Fallot repair: a five-patient case series.
BACKGROUND: Pulmonary regurgitation is a common long-term consequence after Tetralogy of Fallot (TOF) repair and often leads to right ventricular dilatation requiring pulmonary valve replacement (PVR)...
Left and Right Heart Remodelling at 1 Year After Transcatheter Versus Surgical Aortic Valve Replacement: A Speckle-Tracking Echocardiography Study.
OBJECTIVES: Speckle-tracking echocardiography (STE) identifies subclinical myocardial dysfunction after aortic valve replacement. We compared strain-based remodelling and prognostic values after trans...
Transpericardial Left Atrial/Left Ventricular Vent Placement During Robotic Mitral Surgery.
Robotic mitral surgery is one of the most common robotic cardiac procedures being performed, which presents many benefits including smaller incisions, less postoperative pain, quicker recovery, decrea...
A Proposed Anatomical-Fluoroscopic Workflow to Identify the Optimal Split Line for Leaflet Modification in Redo-TAVR.
BACKGROUND: The optimal leaflet modification strategy in redo transcatheter aortic valve replacement (TAVR) needs further refinement. OBJECTIVES: The aims of this study were to clarify the anatomical ...
Leaflet Modification for Redo-TAVR: Impact of Valve Type, Expansion, and Failure Mode-A Bench Study.
BACKGROUND: Leaflet modification (LM) techniques are of interest in redo transcatheter aortic valve replacement (TAVR). However, factors impacting the efficacy of LM are poorly understood. OBJECTIVES:...