Post-Tracheostomy Fistula Formation Between the Trachea and Left Common Carotid Artery in a Pediatric Patient with Trisomy 18.
The long-term survival of individuals with trisomy 18 has improved, and the need for tracheostomy in this population has thus increased. We describe the case of a 3-year-old Japanese boy with trisomy ...
Multimodal Neuroimaging-Based Machine Learning Models Leveraging Cerebral Morphometry and Glymphatic Parameters Predict Short-Term Post-Programming STN-DBS Motor Response in Parkinson's Disease.
BACKGROUND AND OBJECTIVES: Deep brain stimulation of the subthalamic nucleus (STN-DBS) is effective for medication-refractory Parkinson's disease (PD) motor symptoms, but clinical response varies acro...
Left Ventricular Pseudoaneurysm With Acquired Gerbode-Type Defect After Mitral Bioprosthetic Valve Replacement.
We present a 61-year-old woman with progressive dyspnea 20 days after mitral bioprosthetic valve replacement. Multimodality imaging revealed a left ventricular pseudoaneurysm rupturing into the right ...
Non-Invasive Assessment of Left Ventricular Myocardial Work in Conditions Associated With Increased Left Ventricular Wall Thickness.
BACKGROUND: Left ventricular (LV) myocardial work (MW) assessment is a novel non-invasive tool for relatively load-independent assessment of LV myocardial contractile function. In this study, we compa...
One Year of Endurance Exercise Training Does not Improve Vascular Function in Non-Trained Limbs in Healthy Individuals.
Regular endurance exercise is widely recognized for its cardiovascular health benefits, with improvements in vascular function particularly relevant for populations with impaired vascular health. Howe...
Corylin Confers Vasoprotection via JDP2-Nrf2 Antioxidant Axis against Chronic Kidney Disease-Induced Smooth Muscle Cell Remodelling.
Vascular calcification is a pathological process involving vascular smooth muscle cells (VSMCs) phenotypic switching into osteoblast-like cells within a calcium phosphate-deposited environment. This t...
Prognostic Value of the Endothelial Activation and Stress Index (EASIX) in Critically Ill Patients With Ischemic Stroke: A MIMIC-IV Database Analysis.
BACKGROUND: Systemic endothelial dysfunction is a critical driver of poor outcomes in ischemic stroke. We evaluated the prognostic value of the endothelial activation and stress index (EASIX) in criti...
Advances of Fully Biodegradable Poly-p-Dioxanone and Polylactic Acid-Based Polymers as Left Atrial Appendage Closure Devices.
Atrial fibrillation (AF)-related ischemic stroke carries substantial clinical risks, and transcatheter left atrial appendage closure (LAAC) constitutes a core stroke preventive intervention. Conventio...
Radiographic vertebral heart scale and vertebral left atrial size in healthy dogs.
OBJECTIVE: To establish reference values for the vertebral heart scale (VHS) and vertebral left atrial size (VLAS) in clinically healthy dogs and to evaluate their relationship with echocardiographic ...
Phase-Resolved Functional Lung MRI-derived Pulmonary Arterial Pulse Wave Velocity Correlates with 12-Month Mortality in Participants with Pulmonary Hypertension: A Post Hoc Analysis of a Multicenter Study.
Purpose To evaluate pulmonary arterial pulse wave velocity (PWV) derived from phase-resolved functional lung (PREFUL) MRI in participants with suspected pulmonary hypertension (PH), assess its associa...
Interventional Radiology Management After Early Hepatic Artery Thrombosis Following Pediatric Liver Transplantation.
BACKGROUND: Hepatic artery complications are a major cause of early graft loss after liver transplantation (LT), especially in pediatric patients. Traditionally, these complications have been managed ...
Effects of Walnut (Juglans regia L.) on Blood Pressure and Endothelial Function in Adults: A Systematic Review and Dose-Response Meta-Analysis.
BACKGROUND: Walnuts (Juglans regia L.) are rich in bioactive compounds with anti-inflammatory and antioxidant properties, which may benefit cardiovascular health. However, the evidence regarding their...
Modeling Perforator Occlusion After Flow Diversion.
Endoluminal flow diverters are increasingly used to treat cerebral aneurysms. Despite good aneurysm occlusion efficacy, delayed ischemic complications due to side branch or perforator occlusion remain...
Novel Insights from Blood Speckle Imaging for the Assessment of Left Ventricular Flow Dynamics in Adult Patients: A Three-Patient Proof-of-Concept Case Series in the Context of Current Evidence.
Transthoracic echocardiography is the cornerstone of cardiac imaging, yet conventional volumetric and Doppler indices may fail to detect clinically meaningful changes in ventricular performance. Patie...
Beyond Binary: Cardiac Patterning as Probabilistic Fate Restriction.
The mammalian heart is classically described as arising from two cardiac lineages, first and second. Yet, recent lineage tracing of Mesp1 mesoderm and live imaging show that cardiac progenitors are al...
Discovery of Cardioprotective Markers in Huangqi Shengmai Yin via Integrated UHPLC-Q-TOF-MS/MS Fingerprinting, Chemometric Quality Assessment, and Bioactivity Correlation.
Huangqi Shengmai Yin (HQSMY) displays notable cardioprotective properties. Nevertheless, the principal pharmacodynamic constituents underpinning this efficacy have not yet been fully clarified. To tac...
Dietary Vitamin D2 Is Less Potent Than Vitamin D3 at Maintaining or Restoring Structure and Metabolism of Skeletal Muscle and Heart in Male Rats.
Vitamin D (VD) deficiency is prevalent globally. To improve dietary recommendations for food fortification, we used male rats fed with diets depleted of VD or supplemented/rehabilitated with either vi...
A Case of Uterine Arteriovenous Fistula Associated With Adenomyosis and Pregnancy.
Uterine arteriovenous fistula (UAVF) associated with adenomyosis during pregnancy is a rare, life-threatening condition. This report describes a 36-year-old woman with adenomyosis who conceived throug...
AK050834 Deficiency Prevents Vascular Aging via Opposite Regulation of Two Senescence-Sensitive Genes ATF3 and p21.
Vascular aging, not only a victim of vascular cell senescence but also a driving hub of systemic aging, is a complex process in which both anti-aging and pro-aging proteins are involved. Thus, the ide...
From Snapshot to Trajectory: The RV-3 Check for Pulmonary Arterial Hypertension Follow-up.
Pulmonary arterial hypertension follow-up relies on composite clinical risk assessment, yet symptoms and functional markers may not always reflect right ventricular (RV) adaptation. We propose the RV-...