Dietary Interventions for Hypertriglyceridemia.

PURPOSE OF REVIEW: This review summarizes the pathophysiology of hypertriglyceridemia (HTG) and describes the evidence for dietary interventions in the management of HTG. RECENT FINDINGS: HTG is most ...

Breastfeeding Intensity and Early Postpartum Lipid Profiles Among Women With Prior Gestational Diabetes.

IMPORTANCE: Women with prior gestational diabetes are at high risk of cardiometabolic disease, including dyslipidemia, early in the postpartum period. Identifying modifiable factors associated with li...

[Lipid-lowering therapy in transition: implications of the ESC/EAS focused update].

In 2025, the focused update of the ESC/EAS guidelines on dyslipidemia management introduced clinically relevant refinements in cardiovascular risk stratification and lipid-lowering therapy. The update...

Effects of Coffee Decaffeination on Beverage Bioactives, Antioxidant Activity, and Lipid Metabolism in Hyperlipidemic Rats.

The aim of this study was to evaluate the effect of chemical decaffeination on two coffee species (Coffea arabica and Coffea canephora) in terms of the chemical composition of filtered coffee beverage...

Combined Supplementation With Trigonella foenum-graecum and Nigella sativa Seed Powders Improves Glycemic Control, Dyslipidemia, and Organ Function in Alloxan-Induced Diabetic Rats.

Diabetes mellitus is characterized by persistent hyperglycemia accompanied by dyslipidemia, oxidative stress, and progressive hepatic, renal, and hematological disturbances. This study evaluated the c...

Assessment of Hemolysis, Icterus, and Lipemia Interference in 14 Clinical Chemistry and 5 Immunoassay Parameters.

BACKGROUND: Preanalytical interferences caused by hemolysis, icterus, and lipemia (HIL) remain major sources of diagnostic error in clinical laboratories. Manufacturer-declared cutoffs are often based...

[Severe starvation-associated hypercholesterolemia after sleeve gastrectomy and dietary intervention: a case report].

本文报道1例因重度肥胖接受袖状胃切除术的女性，术后8个月体重下降60.0 kg，继而出现血胆固醇、低密度脂蛋白胆固醇水平较术前显著升高。在排除其他病因后，对患者进行饮食干预治疗2个月，其体重从35.0 kg逐渐增至38.1 kg，血脂水平逐渐降至正常范围，在后续随访中，患者体重增至40.0 kg，血脂水平未反弹。.

Plasmapheresis in Hypertriglyceridemia-Associated Acute Pancreatitis: Triglyceride Levels of 5000 mg/dL as a Proposed Threshold.

Severe hypertriglyceridemia-associated acute pancreatitis is a disease with a high mortality rate, and high triglyceride (TG) levels increase the severity of the disease. Standard treatments include f...

The Impact of Lipoprotein apheresis on Plasma Protein Levels: A Meta-Analysis.

Lipoprotein apheresis (LA) is used for severe dyslipidemia but can remove non-lipid plasma constituents. In this systematic review and meta-analysis, we synthesized evidence on LA-associated changes i...

General Hepatology Concerns for the Patient with Cholestatic Liver Disease.

This review provides a clinical summary of the extrahepatic manifestations of cholestatic liver disease that is important for the managing general hepatologist. Drawing on evidence from primary biliar...

Preliminary Validation of a Novel Genetic Knowledge Scale for Familial Hypercholesterolemia: Evaluation of Face Validity and Core Concepts.

Facilitating patient-informed decision making is central to the genetic counseling practice. The Multidimensional Model of Informed Choice (MMIC) evaluates informed decisions in genetic testing, but v...

Genetic polymorphism of CYP3A4 associated with reduced response to statin therapy in Pakistani cardiac and dyslipidemic patients: A cross-sectional observational study.

BACKGROUND: Drug resistance phenomenon has become a serious problem in the lipid lowering drugs in the treatment of cardiac and dyslipidemic patients. Statins are the mainstay pharmacological treatmen...

Association between non-HDL-C and nonalcoholic fatty liver disease (NAFLD) in adults aged 20 years and older: A population-based study in western China.

Dyslipidemia negatively impacts the development of nonalcoholic fatty liver disease (NAFLD); yet, the specific relationship between non-high-density lipoprotein cholesterol (non-HDL-C) and NAFLD has n...

Modeling Inherited Disorders of Post-Lanosterol Cholesterol Biosynthesis: From Animal Models to Patient-Derived Stem Cells.

Altered post-lanosterol cholesterol biosynthesis causes a heterogeneous group of rare inherited metabolic disorders, including Smith-Lemli-Opitz syndrome, desmosterolosis, lathosterolosis, and congeni...

Atorvastatin Mitigates Hypercholesterolemia-Induced Alterations in Cerebral Mitochondrial Dehydrogenases in Rats.

Statins are widely used lipid-lowering agents for the prevention and treatment of cardiovascular disease. Atorvastatin, one of the most frequently used statins, was reported to influence mitochondrial...

The potential regulatory relationship between hsa_circ_0000973 and MBOAT2 in hypertriglyceridemia with abnormal glucose metabolism.

Hypertriglyceridemia (HTG) frequently occurs in population with abnormal glucose metabolism (AGM), exacerbating risk. In our preliminary researches, we have screened hsa_circ_0000973 and MBOAT2 as the...

Effects of ursodeoxycholic acid on statin-induced impaired glucose tolerance: study protocol for a randomized controlled trial.

INTRODUCTION: Statin therapy is associated with an increased risk of dysglycaemia and new-onset type 2 diabetes, which compromises patient adherence. Ursodeoxycholic acid (UDCA), a hepatoprotective dr...

Neonatal Total Parenteral Nutrition and Long-Term Metabolic Outcomes: An 18-Year Nationwide Cohort Study of 2.3 Million Infants.

Background/Objectives: Total parenteral nutrition (TPN) is essential for neonates unable to receive adequate enteral feeding, but its long-term metabolic effects remain uncertain. This study evaluated...

Hypercholesterolemia induced by hypothyroidism is ameliorated by taurine supplementation through the hepatic AMPK/ACC pathway.

OBJECTIVE: To evaluate the effect of taurine supplementation on the lipid profile of male hypothyroid Wistar rats. MATERIALS AND METHODS: Adult male Wistar rats were induced to hypothyroidism by treat...

Association of Thyroid Dysfunction With Dyslipidemia and Metabolic Risk in the Health Examination Population: A Retrospective Analysis.

This study aims to investigate the associative relationships between thyroid dysfunction, dyslipidemia, and other metabolic risks among people undergoing health examinations. 305 individuals undergoin...