High postprandial endotoxemia is associated with recurrence of cardiovascular events in patients with coronary heart disease: from the CORDIOPREV randomized clinical trial.
BACKGROUND: The translocation into the systemic circulation of proinflammatory bacterial components such as lipopolysaccharide (LPS) has been linked to cardiovascular disease (CVD). OBJECTIVES: We aim...
Exercise performance in patients with heart failure and impaired iron transport: a single-centre retrospective study.
OBJECTIVES: Iron deficiency (ID) is frequent in heart failure (HF). Among patients with HF and ID, those with impaired iron transport (IIT) (transferrin saturation (TSAT) <20%) have the worst ID pheno...
Trends in Initial Cardiac Function, Treatment, and Outcomes in Peripartum Cardiomyopathy.
BACKGROUND: Peripartum cardiomyopathy (PPCM) is a rare disease that causes heart failure during pregnancy or in the early postpartum period, and there were no reports on the trend of clinical conditio...
Remote person-centred care and long-term medication management in primary care: post hoc analysis of a randomised controlled trial.
OBJECTIVES: To explore refill adherence to prescribed treatment for chronic heart failure (CHF) and/or chronic obstructive pulmonary disease (COPD), during and after a remote person-centred care (PCC)...
Effect of the ligament of Marshall excision during minimally invasive cardiac surgery-coronary artery bypass grafting (MICS-CABG) on the prevention of postoperative new-onset atrial fibrillation (LOMEX-AF): study protocol for a randomised controlled trial.
INTRODUCTION: Postoperative atrial fibrillation (POAF) remains one of the most common complications following coronary artery bypass grafting (CABG), including minimally invasive cardiac surgery-CABG ...
The Interplay Between Sleep Disturbance, Glymphatic Dysfunction and Altered Brain Networks in Internet Gaming Disorder: A Multimodal Neuroimaging Study.
Sleep disturbances are common in individuals with Internet gaming disorder (IGD), yet the neurobiological links between poor sleep quality and addictive symptoms remain unclear. The glymphatic system ...
Massive haemoptysis secondary to pulmonary artery aneurysms in Hughes-Stovin syndrome: a variant of Behçet's disease managed with immunosuppression and endovascular embolisation.
We report a rare and potentially life-threatening case of a young male with Behçet's disease complicated by Hughes-Stovin syndrome who presented with massive haemoptysis secondary to multiple pulmonar...
Reversible visual loss in biopsy-proven giant cell arteritis.
A late 60s man presented with a 1-week history of recurrent transient monocular visual loss in his left eye, followed by sudden, severe visual loss and eyelid pain. Examination revealed a left relativ...
Cervicothoracic screwdriver impalement causing traumatic aortic injury managed with TEVAR.
Penetrating neck injuries are uncommon but carry high mortality due to the proximity of major vessels and the aerodigestive tract. We report a woman in her 80s who presented with a 40-cm flat-head scr...
Anti-endothelin receptor A autoantibodies associate with immunovascular risk and activate endothelial signalling in SLE.
OBJECTIVE: Cardiovascular disease in SLE is not fully explained by traditional risk factors, supporting a role for disease-specific immunovascular mechanisms. Autoantibodies targeting endothelin recep...
Characterization and outcomes of cats with cardiomyopathy undergoing subcutaneous ureteral bypass device placement.
BACKGROUND: Limited data exist on the characterization and outcomes of cats with cardiomyopathy and benign ureteral obstruction treated by subcutaneous ureteral bypass (SUB) placement. HYPOTHESIS/OBJE...
Immune checkpoint inhibitor-induced myasthenia gravis and myocarditis: a fatal immune-related adverse event.
Checkpoint inhibitors, a class of immunotherapeutic agents, have transformed the oncology landscape by targeting immune checkpoints - regulatory pathways that modulate immune cell activity. By inhibit...
Antihypertensive Efficacy, Safety, and Adherence After Switching From a Free Combination of Bisoprolol/Metoprolol and Amlodipine to Bisoprolol/Amlodipine FDC Tablets (5/5 mg) in Chinese Patients With Hypertension.
Hypertension is a leading chronic disease globally, with rising prevalence in China. A considerable number of hypertension patients struggle to achieve target blood pressure levels with monotherapy al...
METTL3 suppresses pyroptosis in obstructive sleep apnea-associated hypertension via YTHDF2-mediated SOX4 mRNA degradation.
Obstructive sleep apnea (OSA) is frequently complicated by hypertension, with approximately 60% of patients exhibiting both conditions. However, the epigenetic mechanisms underlying this comorbidity r...
An Unusual Etiology of Bayés' Syndrome: Fabry Disease.
We present the case of a 72-year-old female with Fabry disease who developed an advanced interatrial conduction block and atrial fibrillation, a condition known as Bayés' syndrome. Fabry disease is an...
Incidence and Risk Factors of Catheter-Related Thrombosis in Oncology Patients With Internal Jugular and Subclavian Implanted Ports: A Retrospective Single-Center Study.
OBJECTIVE: This study compared the clinical characteristics of catheter-related thrombosis (CRT) associated with internal jugular and subclavian vein-implanted ports. METHODS: This retrospective study...
Neurotensin receptor 2 agonism attenuates adverse cardiac remodeling in preclinical models.
The neuropeptide neurotensin (NTS) is up-regulated in cardiac lymphatic endothelial cells (LECs) in response to ischemic or mechanical damage, but its role in cardiac remodeling is unknown. Here, we a...
Degeneration of Interpericyte Tunneling Nanotubes Can Occur in the Absence of Pericyte Loss in Diabetic Retina Disease.
PURPOSE: Interpericyte tunneling nanotubes (IP-TNTs) synchronize pericyte-pericyte communication and regulate microvascular perfusion, processes disrupted in early diabetic retina disease (DRD). We co...
Clinical Characteristics and Technical Outcomes of Microballoon Catheter-assisted Partial Splenic Embolization.
BACKGROUND/AIM: Partial splenic embolization (PSE) is an established interventional radiology procedure for portal hypertension. However, in cases of splenomegaly with complex vascular anatomy, guide ...
Serum metabolomic signatures integrating sphingosine-1-phosphate and tetrahydrocortisone improve prognostic assessment in non-ischemic cardiomyopathy.
INTRODUCTION: Dilated cardiomyopathy (DCM) and left ventricular non-compaction (LVNC) are major non-ischemic cardiomyopathy (NICM) subtypes with heterogeneous outcomes. Conventional clinical and echoc...