Industry Corner Live With BioBeat CEO Arik Ben Ishay.
Hypertension affects nearly 47% of US adults, yet traditional cuff-based monitoring often fails to provide the longitudinal data required for effective treatment due to patient noncompliance and the p...
Integrated evaluation of genetic and pharmacological RAGE inhibition reveals a multidimensional therapeutic strategy for diabetic atherosclerosis.
Atherosclerotic vascular disease is the major cause of mortality in type 2 diabetes. This study sought to examine the effects of different receptor for advanced glycation end-products (RAGE)-targeted ...
Integrated Computational and Cross-sectional Analysis of Thrombotic Non-coding RNAs as Salivary and Plasma Biomarkers in Coronary Artery Disease.
AIM AND BACKGROUND: Epicardial adipose tissue (EAT), adjacent to the myocardium, plays a role in coronary artery disease (CAD), though its thrombotic mechanisms remain unclear. This study aimed to ide...
From Bridge to Destination: How Next-Generation Ventricular Assist Devices are Redefining End-Stage Heart Failure.
Next-generation LVADs transform heart failure care from transplant bridge to destination therapy.
Extra Vascular-Implantable Cardiodefibrillators: The Best of Both Worlds.
Though their inventor's vision was at first met with intense skepticism, implantable cardioverter-defibrillators have gone through many iterations to become the standard treatment for ventricular tach...
Pulsed Frequency Ablation: The Game Changer for Atrial Fibrillation.
In the search for more effective ways to treat atrial fibrillation and other cardiac arrhythmias, Pulsed Field Ablation has emerged as a way to achieve better outcomes for more patients in a shorter t...
SafeBeat Rx-Moving ECG AI Beyond Diagnostics to Recommending Treatment.
Drug-induced QT prolongation is the leading cause of FDA nonapproval and a key safety concern for many medications, including cardiac drugs, antibiotics, psychotropic drugs, and oncology treatments. C...
PCSK9 inhibitor Evolocumab alleviates atherosclerosis progression by suppressing endothelial cell injury via the ROS/MAPK pathway.
Atherosclerosis (AS) progression is closely linked to oxidized low-density lipoprotein (Ox-LDL)-induced endothelial cell injury. This study investigates the molecular mechanism by which the PCSK9 inhi...
[Open Atrial Transcatheter Mitral Valve Replacement for Mitral Annular Calcification: First Case Report in Chile].
Severe mitral annular calcification represents a significant challenge for valve replacement, particularly in elderly patients with comorbidities, in whom conventional surgical approaches are associat...
[Experience with Percutaneous Placement of an Intra-Aortic Balloon Pump in the Left Axillary Artery as a Bridge to Heart Transplantation: A Case Series].
UNLABELLED: Advanced heart failure (HF) often requires support with vasoactive drugs and mechanical assist devices, such as the intra-aortic balloon pump (IABP), particularly in cases of cardiogenic s...
Management of Arrhythmias During Pregnancy in Africa.
Cardiac arrhythmias represent a significant clinical concern that have been always addressed. Moreover, Pregnancy introduces profound hormonal, autonomic, and hemodynamic changes that add more risk to...
Sleep Disorder Phenotypes and the Risk of Incident Heart Failure: A meta-analysis with Mendelian randomization validation.
OBJECTIVES: To quantify how specific sleep-disorder phenotypes are related to incident heart failure (HF) using a meta-analysis of cohort data and to probe causal relevance via 2-sample Mendelian rand...
[Gene and Cell Technologies for Treatment of Brain Malignancies].
Brain malignancies, such as glioblastoma, remain one of the most aggressive and difficult-to-treat cancers because of their heterogeneity, invasive growth, and resistance to conventional therapy. Sign...
多视角深度学习改善了超声心动图对主要心脏病的检测。
Medical imaging often captures multiple two-dimensional views of three-dimensional anatomic structures, but most artificial intelligence (AI) models analyze two-dimensional data. Here we show that int...
心血管疾病的去中心化临床试验：临床试验医师的引物。
Decentralized clinical trials (DCTs) move trial activities-such as recruitment, consent, delivery of the intervention, data collection and assessment of outcomes-away from traditional research sites t...
The ACEF II scoring model in patients undergoing isolated coronary artery bypass grafting surgery: A single centre validation study.
INTRODUCTION: Estimating the mortality rate of patients after cardiac surgery is an important issue in clinical practice. The age, creatinine, and ejection fraction (ACEF) score is one of those scorin...
Correlates of serum thiamine levels among acute decompensated heart failure patients.
BACKGROUND: Acute decompensated heart failure (ADHF) contributes adversely to health-related outcomes. Anorexia, early satiety, high metabolic rates, malnutrition, advanced age, and diuretic use chara...
Prognostic value of systemic immune-inflammation index in patients with non-valvular atrial fibrillation: SII score in patients using DOACs.
BACKGROUND: The systemic immune-inflammation index (SII) is a simple parameter that has been used to predict adverse outcomes in different clinical settings. The prognostic value of SII, an innovative...
The effects of preoperative haemoglobin levels on early morbidity and mortality in patients undergoing isolated aortic valve replacement.
OBJECTIVE: This study aimed to evaluate the impact of preoperative haemoglobin levels on early morbidity and mortality in patients undergoing isolated aortic valve replacement. MATERIAL AND METHODS: T...
The molecular effects of lepidium sativum extract on damage in rats with cardiac damage caused by total circulatory arrest.
INTRODUCTION: Cardiovascular diseases, which are non-communicable diseases, are among the leading causes of death worldwide. OBJECTIVE: In this study, we aimed to investigate the efficacy of Lepidium ...