重度二叶主动脉瓣狭窄的经导管主动脉瓣置换术
外科主动脉瓣置换术一直是有症状重度退行性主动脉瓣狭窄患者的标准治疗方案。近年来，经导管主动脉瓣置换术在特定患者群体中已成为成熟的替代治疗方案，在三叶瓣狭窄方面有强有力的循证支持。然而，经导管主动脉瓣置换术在二叶主动脉瓣狭窄中的评估仍有限。最近，多项观察性研究证实了经导管主动脉瓣置换术在二叶主动脉瓣狭窄中的可行性和安全性，新一代器械的使用显示出令人鼓舞的结果。然而，与三叶瓣狭窄相比，二叶主动脉瓣狭窄...
重度二叶主动脉瓣狭窄的经导管主动脉瓣置换术
外科主动脉瓣置换术一直是有症状重度退行性主动脉瓣狭窄患者的标准治疗方案。近年来，经导管主动脉瓣置换术在特定患者群体中已成为成熟的替代治疗方案，在三叶瓣狭窄方面有强有力的循证支持。然而，经导管主动脉瓣置换术在二叶主动脉瓣狭窄中的评估仍有限。最近，多项观察性研究证实了经导管主动脉瓣置换术在二叶主动脉瓣狭窄中的可行性和安全性，新一代器械的使用显示出令人鼓舞的结果。然而，与三叶瓣狭窄相比，二叶主动脉瓣狭窄...
短暂性脑缺血发作或轻微脑卒中后中风长期风险的预后因素：系统评价和荟萃分析。
Patients with a transient ischemic attack (TIA) or minor stroke have an increased risk of subsequent stroke that persists for at least 10 years. We aimed to identify prognostic factors associated with...
心房颤动中的左心耳闭合或药物治疗。
Catheter-based closure of the left atrial appendage is an alternative to oral anticoagulation for stroke prevention in patients with atrial fibrillation. The effectiveness of this strategy, as compare...
急性低氧呼吸衰竭中的高流量或标准氧气。
Data are needed on the effect of oxygen delivered through a high-flow nasal cannula, as compared with standard oxygen therapy, on intubation and mortality in patients with acute hypoxemic respiratory ...
前蛋白转化酶枯草杆菌蛋白酶/kexin 9型抑制剂：过去、现在和未来。
On the basis of seminal genetic discoveries, proprotein convertase subtilisin/kexin Type 9 (PCSK9) inhibitors were developed as a new class of LDL cholesterol-lowering drug, with a potency on par with...
早期动脉粥样硬化预防：一种具有成本效益的健康心血管衰老方法。
暂无摘要
The Medium and Long-Term Effects of COVID-19 on the Non-Dipper Blood Pressure Pattern.
OBJECTIVES: Although the COVID-19 pandemic has ended, its long-term cardiovascular effects remain unclear. This study evaluated persistent changes in blood pressure (BP) patterns among recovered COVID...
Thrombus in the Common Carotid Artery Caused by Penetrating Injury with a Bull Horn: A Case Report.
A 40-year-old man was brought to the emergency department after being gored in the neck by a bull. His general condition and vital signs were stable. No neurological deficit was detected. There was no...
促卵泡激素在绝经后女性冠状动脉粥样硬化中的新兴作用：综合综述
绝经后女性心血管疾病的发病率急剧上升，尤其是冠心病，已成为全球女性面临的主要健康问题。以往的观点认为，雌激素水平下降是绝经后女性风险升高的主要原因。近年来，越来越多的证据表明，绝经后水平急剧升高的促卵泡激素（FSH）可能在此过程中发挥关键作用。本文系统总结了来自临床和动物研究的现有证据，评估了FSH与绝经后女性冠心病风险之间的关系，探索了相互矛盾的证据，并检查了其在动脉粥样硬化发病机制和心脏代谢风...
常规公式与机器学习模型估计血清低密度脂蛋白胆固醇的比较
准确估计低密度脂蛋白胆固醇（LDL-C）对于心血管风险评估和监测至关重要。由于β定量法操作繁琐且不适用于常规使用，已开发了多种方程来估计LDL-C浓度。然而，在甘油三酯水平升高、低LDL-C或非空腹样本等临床条件下，传统方程的性能可能下降。本研究比较了常规估计公式（Friedewald、Martin-Hopkins和Sampson-Nielsen公式）与机器学习模型在估计血清LDL-C方面的性能。...
利用冠状动脉钙化评分预测有疑似心脏症状个体中的冠心病：诊断研究
冠心病（CAD）仍然是全球死亡的主要原因，冠状动脉钙化（CAC）作为动脉粥样硬化的标志物已被广泛认识。虽然CAC评分是评估心血管风险的既定无创工具，但其在有疑似心脏症状的个体中预测冠心病的诊断价值仍需进一步评估。本研究旨在探讨CAC评分在预测有疑似心脏症状个体中冠心病方面的诊断性能。研究纳入了因疑似心脏症状转诊进行非对比计算机断层扫描的患者，所有患者随后接受了有创冠状动脉造影作为参考标准。分析了C...
Analysis of the value of stress echocardiography in latent left ventricular outflow tract obstruction in non-hypertrophic cardiomyopathy.
The accurate diagnosis of latent left ventricular outflow tract obstruction (LVOTO) in non-hypertrophic cardiomyopathy (NHCM) is crucial for treatment selection. This study evaluates the diagnostic va...
Clinical and echocardiographic characteristics of patients presenting with pulmonary hypertension due to congenital heart disease.
BACKGROUND: This study aimed to assess patients' clinical and echocardiographic features in pulmonary hypertension (PH) due to congenital heart disease (CHD). METHODS: The main inclusion criterion was...
Cardiometabolic comorbidities associated with androgenetic alopecia: Findings from a sex-stratified, propensity-matched national cohort.
BACKGROUND: To examine associations between androgenetic alopecia (AGA) and cardiometabolic comorbidities in a large, diverse United States cohort with adjustment for socioeconomic and behavioral fact...
Arrhythmia Occurrence After Balloon-Expandable and Self-Expanding Transcatheter Pulmonary Valve Replacement.
BACKGROUND: The incidence of arrhythmias after transcatheter pulmonary valve replacement (TPVR) beyond the early postprocedural period and their relationship to valve type (balloon-expandable [BEPVR] ...
Ventricular Arrhythmias After Self-Expanding Transcatheter Pulmonary Valve Replacement: A Report From the SERVE Registry.
BACKGROUND: Two self-expanding transcatheter pulmonary valves (SETPVs), Harmony TPV (Medtronic) and Alterra Adaptive Prestent System with the Sapien 3 Valve (Edwards Lifesciences), treat pulmonary reg...
Stress-induced cardiomyopathy in the ICU.
Stress-induced cardiomyopathy (siCM), also known as Takotsubo syndrome, is an acute, transient, and typically reversible form of myocardial dysfunction. In the intensive care unit (ICU), siCM remains ...
Cerebrovascular and Bleeding Outcomes of Warfarin versus Direct Oral Anticoagulants Therapy for Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
OBJECTIVES: To compare the effects on cerebral health in atrial fibrillation patients receiving either warfarin or direct oral anticoagulants (DOACs). Atrial fibrillation is linked to a higher likelih...
Management of coronary artery disease via simvastatin-loaded novasomes.
BACKGROUND: Simvastatin (SMT) offers protection against diabetes mellitus related to coronary artery disease (DM-CAD) because of its cardioprotective, antioxidant, and anti-inflammatory effects. Howev...
Variations in basilic vein anatomy in patients undergoing haemodialysis access surgery: A cross-sectional study.
OBJECTIVE: To explore different anatomical variants of basilic veins in patients undergoing haemodialysis access surgery. METHODS: The descriptive, explorative, cross-sectional study was conducted fro...