Clinical and preclinical evidence of meningeal immunity and glymphatic pathways in stroke: a systematic review.

UNLABELLED: Glymphatic transport, meningeal lymphatic drainage, and meningeal immunity have been implicated in metabolic waste clearance, cerebral edema formation, and the regulation of neuroinflammat...

Profiles of medication literacy and associated factors among young and middle-aged hypertensive patients in China: A latent profile analysis.

Improving medication literacy among individuals with hypertension has emerged as a significant public health issue. However, the heterogeneity of medication literacy and its association factors among ...

Supply of interventional cardiologists and the provision of lower-value Percutaneous Coronary Interventions (PCI).

BACKGROUND: Percutaneous coronary interventions (PCI) can be lifesaving for patients with acute coronary syndromes but of lower value for patients with stable coronary artery disease (CAD). Previous s...

Pragmatic cardiovascular-kidney-metabolic burden categories and 5-year all-cause mortality in Vietnamese outpatients: A retrospective cohort study.

BACKGROUND: The American Heart Association introduced cardiovascular-kidney-metabolic (CKM) health as an integrated framework for metabolic, kidney, and cardiovascular risk. However, full AHA CKM stag...

Characterization of aortic endothelial dysfunction in ovariectomized allergic asthmatic mice.

Clinical observations suggest that sex hormones may have a role in female asthma-related cardiovascular diseases (CVD), however, the mechanism by which sex hormones may influence CVD in asthmatics is ...

Development and validation of a nomogram for predicting peripheral atherosclerosis in early-stage type 2 diabetic kidney disease: a retrospective hospital-based study.

INTRODUCTION: Microvascular disease is a common complication of type 2 diabetes mellitus (T2DM). As a typical microvascular complication, diabetic kidney disease (DKD) interacts with peripheral athero...

Cardiovascular composite events and the healthy worker effect among noise-exposed workers: a retrospective cohort study.

BACKGROUND: Occupational noise exposure is prevalent, but its cardiovascular effects are under recognized. Most studies are cross-sectional, focus on single endpoints, and rarely account for the healt...

Association between the C-reactive protein-triglyceride-glucose index and coronary heart disease in metabolic dysfunction-associated steatotic liver disease patients: a cross-sectional study.

BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is strongly associated with coronary heart disease (CHD), but convenient and effective biomarkers for identifying CHD risk ...

Association of triglyceride-glucose and obesity-derived indices with the risk of aortic stenosis among individuals in cardiovascular-kidney-metabolic syndrome stages 0-3: a prospective cohort study from the UK Biobank.

BACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome emphasizes the interplay between metabolic dysfunction, kidney injury, and cardiovascular abnormalities. The triglyceride-glucose (TyG) and i...

Peripheral arterial disease as a risk factor for atrial fibrillation in the postoperative period of myocardial revascularization: a retrospective cohort study.

INTRODUCTION: Postoperative atrial fibrillation (POAF) is the most common complication of myocardial revascularization surgery, associated with predisposing factors and outcomes such as increased hosp...

Physical Activity Levels and Quality of Life in Outpatients with Cardiac Arrhythmias and Preserved Left Ventricular Function: Understanding Their Profile.

Cardiac arrhythmias are heterogeneous conditions that may limit physical activity (PA) and impair quality of life (QoL). To describe levels of PA and perceived barriers as well as to assess their asso...

Association Between Atrial Fibrillation Occurrence and Wolff-Parkinson-White Syndrome: Is Prediction Possible?

BACKGROUND: Patients with Wolff-Parkinson-White (WPW) syndrome frequently develop atrial fibrillation (AF); however, the factors associated with the occurrence of AF remain incompletely defined. OBJEC...

Habitual Oily Fish Intake and Microvascular Integrity in Frequent Fish Consumers: A Population-Based, Cross-Sectional Pilot Study.

ObjectivesMicrovascular health is increasingly recognized as a determinant of functional aging and cardiometabolic risk in aging populations. Marine omega-3 polyunsaturated fatty acids (ω-3 PUFAs), pr...

Vasorelaxant effect of Tribulus terrestris extract and fractions on isolated rat aortae.

Tribulus terrestris (Zygophylaceae) has been used by traditional medicine as tonic, aphrodisiac and diuretic agent, as well as to treat cardiovascular diseases. However, the vascular effect of Tribulu...

Anatomical variability of the superior thyroid artery: a computed tomography-based study in a Polish population and a comprehensive meta-analysis.

BACKGROUND: The superior thyroid artery (STA) shows considerable anatomical variability with important implications for thyroid and laryngeal surgery. Although the external carotid artery (ECA) is the...

Lipidomic Profiling and Biological Aging in Patients with Coronary Microvascular Dysfunction.

BACKGROUND: Coronary microvascular dysfunction (CMD) was frequently encountered in patients with angina in the absence of epicardial coronary stenosis. CMD was associated with adverse outcomes while t...

Overt hyperthyroidism is associated with increased dispersion of ventricular repolarization: a case-control study.

BACKGROUND: Overt hyperthyroidism is associated with increased cardiovascular morbidity, including tachyarrhythmias and heart failure. Although standard electrocardiographic abnormalities are well rec...

Recent research progress and future directions of intracerebral hemorrhage.

Up to now, Intracerebral hemorrhage (ICH) remains a type of cerebrovascular emergency with high incidence, mortality and disability rates. The secondary brain injury following ICH involves a series of...

Global patterns and trends in heart failure burden under chronic respiratory disease cause categories among adults aged 55 years and older: A systematic analysis based on the GBD 2021 Study.

BACKGROUND: Chronic respiratory diseases (CRDs) and heart failure (HF) impose substantial global burdens. However, the long-term population-level burden of HF impairment under CRD cause categories rem...

Anthropometric and Metabolic Traits Across Ancestries in the UK Biobank.

AIMS: Increased waist-hip ratio (WHR) increases free fatty acid (FFA) flux, contributing to dysglycemia and dyslipidemia in Europeans. We examined these phenomena in non-Europeans, a group with higher...