Age-Related Platelet Cox-1 Upregulation in Atrial Fibrillation.
Aging is associated with enhanced platelet activation that may contribute to the occurrence of cardiovascular events. However, the mechanism linking aging with platelet activation is not fully underst...
Real-world off-label apixaban dosing and clinical outcomes in patients with heart failure and end-stage kidney disease.
Apixaban plays a crucial role in preventing cardioembolic events in patients with nonvalvular atrial fibrillation (NVAF). However, in clinical practice, physicians often adjust apixaban dosing based o...
Development and validation of a prediction model for ischemic stroke recurrence risk in patients with ischemic stroke and atrial fibrillation.
BACKGROUND: The recurrence rate of atrial fibrillation (AF)-related ischemic stroke (IS) remains persistently high, significantly increasing patient mortality, disability, and socioeconomic burden. Th...
[Modified Valsalva maneuver induced an asymptomatic polymorphic ventricular tachycardia].
Paroxysmal supraventricular tachycardias (PSVT), including atrioventricular nodal re-entry tachycardia (AVNRT), are commonly treated with vagal maneuvers. The modified Valsalva maneuver, combining for...
Anesthetic management of a pregnant patient with right ventricular outflow tract ventricular tachycardia undergoing cesarean section.
Idiopathic ventricular tachycardia arising from right ventricle outflow tract (RVOT-VT) is an uncommon, catecholamine-sensitive form of VT occurring in the absence of structural heart disease and may ...
Children exposed to hydroxychloroquine in utero show no signs of retinal toxicity at age 5.
OBJECTIVE: Limited examinations from prior studies support the absence of retinal toxicity in infants exposed to maternal hydroxychloroquine (HCQ). However, the infant retina does not have adult morph...
The oblique vein of the left atrium: an overlooked vein in anatomical education with emerging clinical importance in atrial fibrillation ablation.
The oblique vein of the left atrium (Vein of Marshall) is frequently underemphasized in anatomical education and classical texts, often regarded as a minor or vestigial structure. However, contemporar...
Effect of Omega-3 Fatty Acid Intake on Circulating Biomarkers of Atrial Fibrillation-Related Pathways in the PREDIMED-Plus Study.
Background/Objectives: Whether habitual dietary omega-3 fatty acid intake is reflected in circulating biomarkers of atrial fibrillation (AF)-related pathways is unclear. We assessed whether usual diet...
Motif-Level Graph Learning Enables Interpretable Prediction of Drug-Induced QT Prolongation via Cooperative Substructural Determinants.
Drug-induced QT interval prolongation is a critical safety concern in drug development, yet accurate and mechanistically interpretable prediction from chemical structure remains challenging due to the...
A Computationally Efficient Hybrid Approach for Electrocardiogram-Based Arrhythmia Prediction.
Cardiovascular diseases, especially arrhythmias, are a leading cause of death worldwide. This highlights the need for automated systems that can detect and diagnose these conditions early. This resear...
[Integrating Bioinformatics and Machine Learning Algorithms to Screen Inflammatory Biomarkers for Atrial Fibrillation and Experimental Validation].
OBJECTIVE: To identify potential biomarkers of atrial fibrillation (AF) using bioinformatics, machine learning (ML) and experimental methods. METHODS: AF transcriptomic data were obtained from the GEO...
More Than Myocarditis? Cardiac Involvement in Phaeochromocytoma-A Case Report.
AIMS/BACKGROUND: Phaeochromocytoma is a rare catecholamine-secreting neuroendocrine tumour arising from chromaffin cells of the adrenal medulla or from extra-adrenal paraganglionic tissue, in which ca...
Kinesiophobia and associated variables in patients with atrial fibrillation combined with heart failure: A cross-sectional study from China.
OBJECTIVES: While kinesiophobia is a recognised phenomenon in global cardiovascular rehabilitation, its prevalence and characteristics remain unexplored in the specific and growing population of patie...
Clinical Assessment of Thromboembolic Risk in Patients Undergoing Elective Electrical Cardioversion with or Without Transesophageal Echocardiography: A Real-World Observational Study.
Background and Objectives: Elective electrical cardioversion (eECV) in patients with atrial fibrillation (AF) or atrial flutter is associated with a low risk of thromboembolic events (TEs) when adequa...
Impact of new-onset atrial fibrillation on 12-month outcomes and mortality after esophagectomy.
New-onset atrial fibrillation (NOAF) is a frequent complication after esophagectomy. While associated with adverse short-term outcomes, its longer-term cardiovascular impact remains uncertain. We eval...
Wearables for Telemonitoring in ATTR-Amyloidosis: Current Perspectives.
Wearable sensors enable continuous recording of electrocardiographic, photoplethysmographic, and inertial signals and have accelerated the development of digital biomarkers in cardiovascular medicine....
RT-AFNet: A Hybrid ResNet-Transformer Architecture with Multi-Scale Fusion for Atrial Fibrillation Detection.
Atrial fibrillation (AF) is a prevalent cardiac arrhythmia associated with an elevated risk of severe complications, including stroke and heart failure. Due to its paroxysmal nature and the inherent c...
Outcomes of simplified left atrial appendage occlusion using the WATCHMAN FLX device: the ROSE-FLX study.
AIMS: Conventional left atrial appendage occlusion (LAAO) procedures typically require transoesophageal echocardiography and general anaesthesia, which may limit feasibility in resource-limited settin...
Beyond the Maze: Hybrid Ablation and Left Atrial Appendage Occlusion in Cardiac Surgery: Evidence Synthesis and the MESAGE Study Protocol.
Background and Objectives: Atrial fibrillation (AF) is the most common cardiac arrhythmia, present in up to 14-20% of patients undergoing cardiac surgery, with the number of patients expected to doubl...
Arrhythmias in Dengue: A Systematic Review and Meta-Analysis.
BACKGROUND: Cardiac involvement in dengue has been increasingly recognized, yet the true burden and spectrum of arrhythmias remain uncertain due to heterogeneous and fragmented evidence. We conducted ...