Pharmacological rhythm control strategy and outcomes in the oldest atrial fibrillation patients: an analysis of the nationwide Italian START registry.
BACKGROUND: Evidence on antiarrhythmic drugs (AADs) in the oldest atrial fibrillation (AF) patients is limited. We investigated clinical characteristics and outcomes associated with AADs use in this p...
Beyond the CHA2DS2VASc: Hypercoagulable States in Anticoagulated AF Patients.
Despite the proven efficacy of direct oral anticoagulants (DOACs) in preventing thrombus formation in atrial fibrillation (AF), thrombus formation may rarely occur even with appropriate anticoagulatio...
Clinical Outcomes Following PM Implantation: A 3-Year Comparative Study of Sick Sinus Syndrome and Atrioventricular Block.
BACKGROUND: Permanent pacemaker implantation is an established treatment for both sick sinus syndrome (SSS) and atrioventricular block (AVB), yet limited data exist comparing long-term clinical outcom...
Self-testing and clinical outcomes in Black and White patients on warfarin for atrial fibrillation or venous thromboembolism.
BACKGROUND: Warfarin management requires frequent international normalized ratio (INR) testing. Self-testing may reduce this burden and improve INR control and outcomes. However, concerns exist about ...
Prevalence of cardiac arrhythmias in poorly performing horses.
BACKGROUND: Electrocardiogram abnormalities are common in racehorses and can affect performance. AIM: This study aimed to analyze the results of electrocardiographic problems and measure the frequenci...
Long-Term Cardiac Rhythm Monitoring After Ischemic Stroke: Detecting Atrial Fibrillation in the Era of Atrial Cardiopathy.
Long-term cardiac rhythm monitoring has become a central component of the diagnostic evaluation of patients with ischemic stroke in whom atrial fibrillation (AF) is suspected but not initially detecte...
Validation of electronic health record-based International Society on Thrombosis and Haemostasis bleeding algorithms in a US health system.
BACKGROUND: Novel algorithms were developed to identify International Society on Thrombosis and Haemostasis (ISTH)-defined major and clinically relevant nonmajor (CRNM) bleeding events using electroni...
Clinical profile and mortality predictors in cardiac sarcoidosis: A single centre observational study.
Background Cardiac sarcoidosis (CS) may present with conduction abnormalities, ventricular arrhythmias, and heart failure. The delay in recognizing cardiac involvement in systemic sarcoidosis leads to...
Direct Oral Anticoagulants, COX-2-Selective NSAIDs, and Gastrointestinal Bleeding in Atrial Fibrillation.
IMPORTANCE: It is unclear whether the beneficial effects of nonsteroidal anti-inflammatory drugs (NSAIDs) that selectively inhibit cyclooxygenase 2 (COX-2) in decreasing the risk of gastrointestinal (...
Effects of Diazepam Addition to Standard Treatment of Atrial Fibrillation in Emergency Department Settings: A Unicentric Retrospective Study.
Background and Objectives: Diazepam, a GABAA receptor agonist with sympatholytic properties, is sometimes co-administered with antiarrhythmic agents in the emergency management of atrial fibrillation ...
Calcium Channel Blockers in Critical Care Medicine: Current Clinical Applications and Future Investigational Perspectives.
Calcium channel blockers (CCBs) are frequently used in the emergency department and intensive care unit for a wide range of critical conditions, including atrial fibrillation, hypertensive emergencies...
Pilot Study Comparing Emergency Physician and Artificial Intelligence-supported Interpretations of Electrocardiograms.
BACKGROUND: Artificial intelligence (AI) tools are increasingly being explored for medical applications; however, their effectiveness in emergency electrocardiogram (ECG) interpretation is under-inves...
Complete Recovery of Thyrotoxicosis Cardiomyopathy After Antithyroid and Corticosteroid Therapy: A Case Report.
Thyroid storm (TS) is an extreme hypermetabolic state due to thyrotoxicosis. TS may manifest as cardiovascular symptoms, including atrial fibrillation (AF) (9 - 23%) and heart failure (HF). Dilated ca...
Beyond the Irregular Beat: An Unexpected Case of Raynaud's Phenomenon in a Patient with Atrial Fibrillation.
Raynaud's phenomenon is characterized by episodic vasospasm of the extremities, often triggered by cold or stress. It is a hallmark of systemic sclerosis (SSc) and is frequently associated with pulmon...
Radiofrequency Ablation for Treating Cardiac Arrhythmias in Brazil: Status in the Unified Health System.
BACKGROUND: Cardiac arrhythmias compromise quality of life and are associated with greater morbidity and mortality. Pharmacological treatment generally has limited efficacy and often causes adverse ef...
Can Lactate Values Predict Postoperative Atrial Fibrillation Following Coronary Artery Bypass Graft Surgery? A Prospective Observational Study.
INTRODUCTION: The aim of our study is to investigate the relationship and predictive significance of routinely measured serum lactate values with postoperative atrial fibrillation (POAF) in patients f...
Current evidence of gut microbiota dysbiosis and its role in atrial fibrillation and cardiovascular diseases.
The human gut microbiota has emerged recently as an important regulator of cardiovascular physiology through its effects on metabolism, immune signaling, and systemic inflammation. Increasing evidence...
使用基于心电图的深度学习预测应激相关心房颤动后的复发和结局。
Stressor-associated atrial fibrillation (AF) refers to new-onset AF that occurs with a reversible, acute stressor. Identifying individuals at highest risk for AF recurrence is essential to guide manag...
Lgi3-4蛋白调节KV1.5通道小体，是心房颤动的潜在治疗靶点。
We investigated the role of Lgi3-4 proteins in cardiac electrophysiology, with a specific focus on IKur, and their potential contribution to the pathophysiology of atrial fibrillation (AF). In human a...
美金刚治疗房性早搏：一项II期随机临床试验
房性早搏是最常见的心律失常之一，频繁的房性早搏可增加房颤、卒中和心力衰竭的风险，但目前尚无批准的特异性治疗药物。本研究为一项II期随机临床试验，旨在评估美金刚（一种NMDA受体拮抗剂）治疗房性早搏的疗效和安全性。美金刚通过阻断NMDA受体介导的过度交感神经激活，理论上可以减少房性异位激动。研究纳入了频繁房性早搏患者，随机分配至美金刚治疗组和安慰剂组，通过24小时动态心电图评估房性早搏负荷变化。主要...