Hemodynamic gain index (HGI) is a novel, simple parameter calculated from resting and peak systolic blood pressure (SBP) and heart rate (HR) during exercise, but its prognostic value in patients with ...
Hemodynamic gain index (HGI) is a novel, simple parameter calculated from resting and peak systolic blood pressure (SBP) and heart rate (HR) during exercise, but its prognostic value in patients with ...
Pharmacologic management after Takotsubo syndrome remains empirical.
Patients with significant aortic regurgitation (AR) not meeting current surgical criteria may develop heart failure with preserved ejection fraction (HFpEF). Left atrial reservoir strain (LASr) reflec...
Microvascular obstruction (MVO) frequently occurs after primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) and can be classified as tr...
In patients with angina despite non-obstructive coronary arteries (ANOCA), coronary vasomotion disorders (CVD) are a common cause for their symptoms. Due to the heterogeneous clinical presentation res...
Left ventricular diastolic dysfunction following Takotsubo syndrome (TS) and ST-elevation myocardial infarction (STEMI) is a marker of impaired myocardial relaxation and reduced ventricular compliance...
Conduction system disturbances resulting in permanent pacemaker implantation (PPI) are common complications after transcatheter aortic valve implantation (TAVI). In some patients, there is delayed rec...
Deep learning prediction of left atrial structure and function from 12-lead electrocardiograms.
Abnormal cardiac atrial structure and function, termed atrial cardiopathy, typically precedes atrial fibrillation and downstream cardiovascular complications, yet detection is limited by the cost and ...
Cilioretinal Artery Occlusion Associated with Progressive Optic Nerve Head Ischemic Involvement: A Case Report.
Cilioretinal artery occlusion is an uncommon retinal vascular emergency that can cause acute monocular visual loss, particularly when the macular region is involved. Non-arteritic anterior ischemic op...
SGLT2 inhibition improves sarcomere contractile dysfunction in human models of dilated cardiomyopathy.
BACKGROUND: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are now widely applied in treatment plans for heart failure with reduced ejection fraction (HFrEF) patients, regardless of the presence o...
Body mass index predicts ventricular repolarisation in obese children: differential effects across obesity levels.
BACKGROUND: Childhood obesity is associated with cardiac electrical remodelling, yet the relationship between body mass index (BMI) and ventricular repolarisation (VR) heterogeneity remains incomplete...
Low versus high inferior mesenteric artery ligation and gastrointestinal quality of life following anterior resection for rectal cancer.
AIM: To assess whether the level of inferior mesenteric artery (IMA) ligation independently affects gastrointestinal-specific quality of life after anterior resection for rectal cancer. METHODS: A pro...
Systemic Neutralization of Granulocyte-Macrophage Colony-Stimulating Factor Attenuates Stellate Ganglion Neuroinflammation and Cardiac Sympathetic Overactivation in Chronic Heart Failure in Rats.
Chronic heart failure (CHF) is characterized by heightened cardiac sympathetic activity and neuroinflammation within the stellate ganglia (SG), contributing to cardiac arrhythmogenesis. However, the u...
Single-cell analysis of the progeria arterial wall reveals progerin-induced progressive, cell type-specific dysfunction and somatic mutation accumulation.
BACKGROUND: The premature aging disorder Hutchinson-Gilford Progeria Syndrome (HGPS) is caused by de novo LMNA mutations producing the aberrant Lamin A isoform progerin. HGPS patients die from cardiov...
Combined carotid endarterectomy and bypass for multi-level supra-aortic occlusive disease.
Occlusion of the subclavian artery is an important cause of upper limb ischaemia and vertebrobasilar insufficiency. When associated with carotid artery occlusion, management becomes complex and techni...
Engineered heart-liver axis nanoregulators synergize autophagy activation and systemic metabolic reprogramming against atherosclerosis.
Atherosclerosis (AS) is the most important pathological basis for cardiovascular diseases worldwide. However, the current mainstream therapeutic strategies for AS only target isolated pathological lin...
Evidence summary of nursing care of arterial drug administration and catheter management for HAIC in hepatocellular carcinoma.
BACKGROUND: This study aimed to summarize and grade the existing evidence on continuous hepatic artery infusion chemotherapy (HAIC) arterial drug administration and catheter care, providing evidence-b...
Mechanical vs. sutureless aortic valve replacement: clinical outcomes and the contribution of preoperative multislice CT.
INTRODUCTION: Heart valve disease is a significant cause of morbidity and mortality, and aortic valve replacement (AVR) is a common treatment option. Recently, sutureless biological valves have gained...
Dual-Metal Regulation of Cardiac Remodeling: Targeting the LOXL2-Ferroptosis Axis in Metal-Induced Cardiac Dysfunction.
Cardiac remodeling is driven by progressive extracellular matrix stiffening and cardiomyocyte loss. Cardiomyocyte death arising from the progression of fibrosis and ferroptosis, which are regulated by...