Assessing Murine Aortic Intrinsic Stiffness Using Pin Myography: A Translational Framework For Interrogating The Influence of the Circulating Milieu.
Aortic stiffening is an independent risk factor for cardiovascular disease and other chronic conditions, including cognitive decline, kidney dysfunction, vision impairment, and reduced glucose-insulin...
Ultra-Delayed Intracardiac Cement Embolism After Percutaneous Vertebroplasty: A Case Report and Review of Management Strategies.
Cardiac cement embolism is a rare but potentially life-threatening complication of percutaneous vertebroplasty, usually occurring during or shortly after the procedure. Delayed presentations remain po...
Experimental Investigation into Bipolar Sealability of Elastin-Rich Tissue.
BACKGROUND: Elastin-rich vessels such as the aorta pose a particular challenge for bipolar tissue sealing due to their high elasticity and low compressibility. It is unclear under which conditions a m...
FedHSFV: Federated Learning for Finger Vein Recognition via Hierarchical Decoupling and Subspace Metric.
Finger vein recognition (FVR) has significant potential in biometrics due to its high accuracy and intrinsic liveness detection capabilities. However, the increasingly stringent privacy regulations ha...
Vascular Endothelial Barrier in Salivary Glands: From Physiological Regulation to Pathological Impairment of Secretion.
Although salivary glands are highly vascularized, the microvascular endothelial barrier has only recently emerged as a pivotal determinant of glandular homeostasis and disease. This review synthesizes...
The Immunologic Function of the Choroid Plexus: A Gateway to Immunomodulatory Therapy in Injury Models of the Central Nervous System.
Over time, our understanding of the central nervous system (CNS) as an immunologically privileged site where immune-cell infiltration takes place has changed; research has transformed the dominant vie...
Hunting for an Antigen: Humoral Immunity in Alzheimer's Disease.
Alzheimer's disease (AD) is the leading cause of dementia, affecting millions of individuals on a global scale. A fatal and incurable neurodegenerative disease, AD is defined by various molecular and ...
Sex-Dependent Vascular Responses to Atorvastatin Across Multiple Arterial Beds in a Mouse Model of Marfan Syndrome.
Marfan syndrome (MFS) is characterized by progressive aortic aneurysm formation resulting from mutations in the fibrillin-1 (Fbn1) gene. Although the thoracic aorta is the primary site of pathology, a...
Non-catheter-adherent right atrial mural thrombus in a patient with systemic sclerosis undergoing hemodialysis: a case report.
Catheter-related right atrial thrombosis is a rare, potentially fatal complication of central venous catheterization. While most reported cases involve thrombi attached to the catheter tip or mobile i...
Glymphatic dysfunction associates with regional white matter hyperintensities and plasma amyloid-β burden across the Alzheimer's disease continuum.
BACKGROUND: Glymphatic system dysfunction has been increasingly implicated in Alzheimer's disease (AD), yet its relationships with cerebral small vessel disease (CSVD), plasma biomarkers, and cognitiv...
A Communicating Anomalous Vessel Between the Brachial and Radial Artery: A Cadaver Case Report.
BACKGROUND The arrangement of the arm vasculature is known to vary between individuals with a majority being clinically silent. In this report, we describe a rare arterial anomaly in which a branch ar...
Left ventricular excessive trabeculation: pathophysiology, diagnostic challenges, and prognostic significance.
Excessive trabeculation has been considered the morphological hallmark of left ventricular non-compaction (LVNC), traditionally viewed as a primary cardiomyopathy resulting from an arrest in myocardia...
Sirtuin 1 deficiency mediates chronic kidney disease-induced inflammaging cardiovascular calcification.
Chronic kidney disease (CKD) markedly accelerates calcific aortic valve disease (CAVD), yet the underlying mechanisms and therapeutic targets remain poorly defined. Here, we integrate population-scale...
Neuropeptide signaling and the blood-brain barrier generate a persistent stress-induced internal state in Drosophila.
Although fear conditioning has elucidated cue-evoked acute fear responses, the mechanisms by which stress experiences induce generalized internal states linked to anxiety or phobia are poorly understo...
Chronic limb-threatening ischemia (CLTI) caused by infrapopliteal disease is a major therapeutic challenge, with percutaneous transluminal angioplasty (PTA) associated with high rates of restenosis an...
Kawasaki disease (KD) is an acute medium-size vasculitis that affects the coronary arteries. Untreated children can develop coronary artery aneurysms with a prevalence of ≈25%, but prompt treatment wi...
The clinical benefit of intensive LDL-C-lowering with evolocumab in patients with prior percutaneous coronary intervention (PCI) but without a prior myocardial infarction (MI) is not established.
Young athletes and adolescents with high cardiorespiratory fitness appear to have a higher risk of atrial fibrillation (AF), but the extent to which this reflects causal effects or shared genetic, beh...
There is interest in developing lipoprotein(a) [Lp(a)] lowering therapies. Cholesteryl ester transfer protein inhibitors lower Lp(a), however the effects of the selective inhibitor obicetrapib on Lp(a...
Weight loss and weight loss maintenance are prominent topics of discussion for clinicians and health professionals involved in treatment to reduce obesity and the risk of cardiovascular disease. Becau...