The Evolving Role of Coronary Artery Imaging in Assessing Cardiovascular Risk from Lipoprotein(a).
PURPOSE OF REVIEW: Summarize current literature on the use of coronary artery imaging modalities in examining the atherosclerotic and arterial inflammatory manifestations of elevated lipoprotein(a) [L...
Nicotinamide mononucleotide ameliorates high glucose/high fat-induced cardiomyocyte metabolic dysfunction through SIRT1-mediated CPT1A stabilization.
OBJECTIVE: To investigate the mechanism of nicotinamide mononucleotide (NMN) in ameliorating high glucose/high fat (HG/HF)-induced metabolic dysfunction in diabetic cardiomyopathy (DCM) through SIRT1-...
A conceptual review of intracellular pH as a regulator of the adenosine-L-arginine-nitric oxide (ALANO) axis in human fetoplacental endothelial dysfunction in gestational diabetes mellitus.
This conceptual review provides a synthesising narrative of the interdependent regulation of intracellular pH (pHi), nitric oxide (NO), and adenosine-the pHi-NO-adenosine triad-in fetoplacental endoth...
The Role of miR-501-3p in Abdominal Aortic Aneurysm Progression: A Pilot Study.
MiR-501-3p, a small non-coding RNA, has been linked to vascular damage and arterial stiffness, but its role in abdominal aortic aneurysm (AAA) remains unknown. Blood exosomal microRNAs were extracted,...
Bioelectrical Regulation of Vascular Endothelial Function in Atherosclerosis.
Atherosclerosis is a chronic inflammatory disease characterized by progressive vascular dysfunction and remains a leading cause of cardiovascular morbidity and mortality worldwide. Endothelial dysfunc...
Retinal Structural and Microvascular Findings on OCT and OCTA in Hemodialysis and Kidney Transplant Recipients and Their Association with Mineral Metabolism Parameters.
BACKGROUND: Chronic kidney disease (CKD) is associated with systemic microvascular dysfunction, yet the relationship between retinal changes and mineral metabolism disturbances across CKD treatment mo...
Successful off-label use of vascular closure devices in fully percutaneous transaxillary aortic valve implantation.
BACKGROUND: The axillary artery is an alternative access- site for transcatheter aortic valve implantation (TAVI) when femoral arteries are unfavourable. Simplified transaxillary-TAVI (TAx-TAVI) is pe...
Prevalence and burden of coronary artery disease in young adults undergoing clinically indicated coronary CT angiography.
BACKGROUND: The reported prevalence and burden of coronary artery disease in young adults varies markedly in published studies from the 1950s through 2000s but has not been evaluated in a large contem...
Left pulmonary artery sling in an infant: a vascular anomaly with a high impact on breathing.
An infant presented with persistent stridor and recurrent respiratory distress since birth. Imaging revealed a left pulmonary artery sling causing significant tracheal compression. Surgical reimplanta...
Factors Modulating Mitochondrial Function after Arterial Injury: Past-to-Present Evidence for the Devising of Future Preventive and Therapeutic Strategies.
Vascular trauma can lead to adverse outcomes if remodeling is uncontrolled. Intimal hyperplasia (IH) is a key process that contributes to luminal narrowing during remodeling and is strongly influenced...
Repeatability of cerebral arteriovenous pulse wave propagation in flow-related enhancement MRI.
Flow Related Enhancement (FREE) MRI is a non-contrast technique for temporally resolved cerebral pulse-wave analysis. Clinical implementation requires proven repeatability. We aimed to evaluate the in...
Integrating RV-PA coupling and geometry-based indices into the TRI-SCORE improves prognostic assessment in tricuspid regurgitation.
BACKGROUND: Tricuspid regurgitation (TR) is a progressive and underdiagnosed condition associated with poor prognosis. Although the TRI-SCORE is a validated risk model for patients undergoing tricuspi...
Cryptogenic stroke in a young adult due to pulmonary arteriovenous malformation.
Pulmonary arteriovenous malformations (PAVMs) are rare vascular anomalies that create a right-to-left intrapulmonary shunt, allowing embolic material to bypass the pulmonary capillary filter and enter...
PD-1/PD-L1 inhibitor induces systemic inflammation and alters cardiac lipid metabolism in C57BL/6 J mice.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy, and their side effects, such as cardiotoxicity, have become critical complications. Herein, we explored the potential mechanism ...
Dimethyl itaconate preserves cardiac function and reduces remodeling via anti-fibrotic actions in rats.
BACKGROUND: Cardiac hypertrophy is a pathological condition associated with the enlargement of the heart muscle and serves as a risk factor for heart failure. Itaconic acid is a metabolite produced by...
The middle hepatic artery: prevalence and origin patterns of a distinct segment 4 artery.
BACKGROUND: The middle hepatic artery (MHA) is commonly used to describe the artery supplying segment 4 of the liver. Because preservation of segment 4 inflow is important in hepatobiliary surgery, es...
Association between intradialytic blood pressure and left ventricular mass index in end-stage renal disease.
AIM: To evaluate whether single and two-month average intradialytic blood pressure (BP) measurements, including systolic blood pressure (SBP) and diastolic blood pressure (DBP), are associated with le...
Exercise-Induced ECG Abnormalities in Pediatric Pectus Excavatum: Evidence of Right Ventricular Compression Beyond the Haller Index.
BACKGROUND: Pectus excavatum (PEX) is the most common congenital chest wall deformity and may result in cardiac compression and arrhythmias. The relationship between structural severity and exercise-i...
Molecular profiling of the single-cell proteome via gel electrophoresis and 3D single-molecule imaging.
Recent advances in shotgun proteomics and immunoassays have yielded powerful single-cell proteomics technologies. However, current methods lack the sensitivity required to comprehensively quantify pro...
Mast Cells in the Developing Brain.
Brain development requires the coordination of numerous cell types including neurons, glia, and immune cells. Mast cells (MCs) are tissue-resident innate immune cells canonically known for their role ...