Artificial Intelligence-Based Analysis of Coronary Atherosclerotic Plaque on Intravascular Ultrasound: A Systematic Review and Meta-Analysis.

BACKGROUND: Coronary atherosclerotic plaque detection is essential for the diagnosis and management of coronary artery disease. Although intravascular ultrasound (IVUS) enables detailed plaque assessm...

Atrial Cardiopathy in Embolic Strokes of Undetermined Source.

BACKGROUND: Embolic Strokes of Undetermined Source (ESUS) accounts for about 9-25% of all ischemic strokes. Atrial cardiopathy (AC) is a recently described pathology of the left atrium and is found to...

The Pretemporal Transcavernous Approach to the Posterior Clinoid Process Chondrosarcoma with Intraoperative Neuromonitoring.

The pretemporal transcavernous approach (PTTCA) is used for complex aneurysms and skull base tumors. Four levels of PTTCA have been described depending on the extent of exposure of the cavernous sinus...

Myocardial Stress Biomarkers and Inflammatory Indices in Cattle With Bovine Respiratory Disease Complex.

BACKGROUND: Bovine respiratory disease complex (BRDC) is primarily considered a pulmonary disorder; however, hypoxia and systemic inflammation associated with this condition may also impose cardiovasc...

Disease-Phase Myocardial Dysfunction by Strain Imaging in Kawasaki Disease: A Systematic Review and Meta-Analysis.

BACKGROUND: Global longitudinal strain (GLS) can detect subclinical dysfunction missed by left ventricular ejection fraction (LVEF). We aim to quantify the magnitude of myocardial dysfunction using GL...

L-DOPA Promotes Post-Treatment Neurovascular and Synaptic Homeostasis in Early Diabetic Retinopathy.

PURPOSE: Although previous work has shown a post-treatment protective effect of levodopa (L-DOPA) on retinal function in early-stage diabetic retinopathy (DR) in humans, its underlying biology is unkn...

Qiliqiangxin Improves Cardiac Glucose Metabolism After Myocardial Infarction Through a HIF-1α/MIF/AMPK Axis.

Cardiac glucose metabolism is critically involved in the pathophysiology of myocardial infarction. This study investigated whether Qiliqiangxin (QL), a traditional Chinese medicine, improves myocardia...

Effects of Combined Training on Cardiac Autonomic Modulation in Asthmatic Adolescents.

OBJECTIVE: Exercise-induced bronchoconstriction (EIB) is defined as the acute narrowing of the lower respiratory airways after exercise. This study aimed to verify the behavior of cardiac autonomic mo...

Salvianolic Acid B Upregulates miR-744-5p Expression in Peripheral Blood Mononuclear Cell-Derived Extracellular Vesicles to Alleviate Uremic Cardiomyopathy.

Uremic cardiomyopathy (UCM) is a severe complication of uraemia that lacks effective treatments. The role of immune dysfunction in haemodialysis patients with UCM remains unclear. Peripheral blood mon...

[Isolation, expansion, and identification of the perivascular adipose-derived mesenchymal stem cells from rat aortas].

Objective To establish a method for isolating and expanding perivascular adipose-derived mesenchymal stem cells (PV-ADSC) from rat aortas and to provide a reliable cellular model for investigating vas...

Multi-Target Cardioprotective Potential of Garcinia indica Choisy in Olanzapine-Induced Cardiometabolic Dysregulation: Evidence From Computational and Experimental Insights in H9c2(2-1) Cells.

Olanzapine (OLZ), a commonly prescribed atypical antipsychotic, is strongly linked to cardiometabolic disorders (CMDs) such as obesity, insulin resistance, dyslipidemia, and cardiac dysfunction. Garci...

Latent Vasculopathy of a Peripheral Pulmonary Artery in FBN1-Related Marfan Syndrome.

Marfan syndrome (MFS) is a hereditary connective tissue disorder characterized by cardiovascular and skeletal abnormalities. While cardiovascular pathology is well described, the microscopic features ...

Quantitative Analysis of the Heart Development of Podocnemis unifilis (Podocnemididae, Testudines): A Stereology Study.

The present study investigated the cardiac development of the Amazonian turtle Podocnemis unifilis during its embryonic phase, from the 5th to the 59th day of incubation, with emphasis on the volumetr...

Comprehensive Evaluation of YJ-2 as a PAD4 Inhibitor in Alleviating Ischemic Brain Injury: From NETs-Induced Neurotoxicity to In Vivo Neuroprotection.

AIMS: To evaluate the neuroprotective potential of YJ-2, a novel peptidylarginine deiminase 4 (PAD4) inhibitor, against ischemia/reperfusion brain injury by targeting neutrophil extracellular trap (NE...

Reduced Complement and Granulocyte Activation by α-Gal Knockout Porcine Pericardium for Bioprosthetic Heart Valves: A Pilot Hemocompatibility Study.

Xenogeneic pericardium is the main source for biological aortic valve prostheses. Immune responses to α-Gal epitopes and free aldehyde groups after glutaraldehyde (GA) fixation are responsible for the...

Hydroxychloroquine and the cardiovascular system: lights and shadows.

OBJECTIVES: To review the dual impact of hydroxychloroquine (HCQ) on the cardiovascular system, focusing on both its cardioprotective effects and potential cardiotoxicity in patients with autoimmune d...

Computed Tomography Angiography-Based Mapping of Septocutaneous Fibular Artery Perforators: An Anatomical Analysis.

BACKGROUND: Reliable localization of septocutaneous fibular artery perforators is essential for fibula free flap planning. However, the influence of lower-leg vascular anatomy on perforator number and...

Vascular-Apoptotic Crosstalk in Alzheimer's Disease: The Possible Role of Vascular Senescence in Blood-Brain Barrier Dysfunction.

BACKGROUND: Blood-brain barrier (BBB) dysfunction is an early feature of Alzheimer's disease (AD), influenced by amyloid pathology, astrocyte activation, and vasoactive mediators such as endothelin-1 ...

Quantifying Lateral Pulsation in Retinal Vessels Within the Optic Disc.

PURPOSE: The retina provides a noninvasive window for imaging vascular pulsation in the optic disc. Pulsation characteristics reflect vascular stiffness, hemodynamics, and ocular pressure dynamics, us...

The Effect of Chronic Angiotensin (1-7) Treatment on Functional Responses of Isolated Resistance Arteries in Streptozotocin-Induced Diabetic Rats.

Cardiovascular complications of diabetes mellitus (DM) are responsible for morbidity and mortality in DM patients. Recent evidence highlights the pathophysiological role of the renin-angiotensin-aldos...