Primary Leiomyosarcoma of the Superior Vena Cava: A Rare Case Report.

Leiomyosarcoma of the superior vena cava (SVC) is an exceptionally rare vascular tumor. Fewer than 20 cases were reported worldwide. Because of the nonspecific nature of the presenting symptoms and th...

The expanding role of peptides in cardiovascular care.

Peptides have emerged as key regulators of cardiovascular physiology and increasingly important tools in the diagnosis and management of cardiovascular disease (CVD). Endogenous peptide systems, inclu...

Diagnostic Role of Celiac Plexus Block in Assessing Eligibility for Corrective Surgery in a Case of Median Arcuate Ligament Syndrome.

BACKGROUND: Median arcuate ligament syndrome (MALS) is an uncommon cause of postprandial abdominal pain that can be difficult to diagnose, especially in children. CASE REPORT: We report a 14-year-old ...

Effect of Gene Expression Profiling Surveillance Compared With Endomyocardial Biopsy On Tricuspid Regurgitation in Patients with Heart Transplant.

OBJECTIVES: Gene expression profiling is an emerging noninvasive method for rejection surveillance in heart transplants. Tricuspid regurgitation prevalence increases over time after heart transplant, ...

[Migration of a contraceptive implant into the pulmonary artery].

Each year, in Belgium and Europe, thousands of contraceptive implants are inserted, representing an effective and long-lasting method of contraception. Their ease of use and prolonged duration of acti...

[Coronary artery anomalies associated with bicuspid aortic valve].

Bicuspid aortic valve (BAV) is the most common congenital heart disease. It is often associated with aortic abnormalities and, more rarely, with coronary anomalies that may influence surgical strategy...

[Compound Ciwujia Granules for chronic fatigue syndrome with syndrome of deficiency of both heart and spleen: a multicenter, randomized, double-blind, double-dummy, positive drug-controlled trial].

This study aimed to evaluate the clinical efficacy and safety of Compound Ciwujia Granules in patients with chronic fatigue syndrome with syndrome of deficiency of both heart and spleen. It adopted a ...

[Study on mechanism of Zhenwu Decoction against heart-kidney Yang deficiency-induced heart failure via cAMP/PKA signaling pathway].

This study aimed to investigate the effects of Zhenwu Decoction(ZWT) on cardiac fibrosis in mice with heart-kidney Yang deficiency-induced chronic heart failure(CHF). The research further explored the...

[Roles of vascular smooth muscle cells phenotype transformation in mediating progression of diabetic macroangiopathy and current status of traditional Chinese medicine treatment].

Diabetic macroangiopathy, a major chronic complication of diabetes, is characterized by atherosclerosis. Its pathological core involves the phenotype transformation of vascular smooth muscle cells(VSM...

[Costunolide improves sorafenib-induced cardiomyocyte injury by inhibiting mitophagy].

This study focused on the protective effect of costunolide(COS) against sorafenib(SOR)-induced cardiomyocyte injury and its association with mitophagy. Cell viability was assessed using the CCK-8 assa...

Homocysteine-induced endothelial dysfunction through mediating endoplasmic reticulum stress.

ObjectiveEndothelial dysfunction is a key pathological process in cardiovascular and cerebrovascular diseases. Herein, we aimed to investigate the effect of homocysteine on endoplasmic reticulum stres...

Treatment of Portal Biliopathy-Related Bile Duct Stricture Using a Two-Step Approach: Proximal Splenorenal Shunt and Roux-en-Y Hepaticojejunostomy.

Portal biliopathy, also referred to as portal cavernoma cholangiopathy, is a biliary complication of extrahepatic portal vein obstruction caused by cavernomatous transformation of the portal vein and ...

Synchronized left anterior/posterior fasciculars pacing - a modified strategy for difficult left ventricular lead implantation during CRT-D: A case report.

Cardiac resynchronization therapy - defibrillator (CRT-D) is an effective treatment for ischemic heart failure (HF). But, it is a tricky challenge for left ventricular lead implantation difficulties d...

Let-7e-5p promotes cardiac hypertrophy by targeting LBH and regulating the IGF-PI3K-AKT signaling pathway.

BACKGROUND: Cardiac hypertrophy refers to the compensatory response of the heart to various physiological or pathological stimuli in order to maintain its function. Let-7e-5p has been reported to be u...

Sepsis-Related Coronary Endarteritis With Multiple Coronary Artery Thrombi and Acute Myocardial Infarction.

Histological examination revealed acute myocardial infarction in the anterior wall and ventricular septum, with in-stent occlusive thrombosis overlying neoatherosclerosis in the left anterior descendi...

Does Venous Drainage Route Matter? Portal Versus Systemic Drainage in Isolated Intestinal Transplantation: An Analysis of the National UNOS Database.

BACKGROUND: Type of venous drainage in isolated intestinal transplantation (ITx) may influence immune responses through hepatic filtration of gut-derived antigens and affect outcomes. METHODS: We anal...

Nanomedicine for Glioblastoma Therapy: Novel Insights and Future Perspectives.

Glioblastoma (GBM) remains one of the most aggressive primary brain tumors, with poor prognosis, high recurrence, and limited therapeutic options. Although substantial progress has been made in drug d...

Left Atrial Reservoir Strain Combined With Left Ventricular Longitudinal Strain Improves Discrimination of HFpEF in Patients With Hypertension.

Early identification of heart failure with preserved ejection fraction (HFpEF) in hypertensive patients remains challenging using conventional parameters alone. This retrospective study aimed to asses...

Evaluation of the effect of mavacamten on left ventricular function in obstructive hypertrophic cardiomyopathy using myocardial work.

OBJECTIVE: To evaluate the effect of 12-week Mavacamten on left ventricular function in obstructive hypertrophic cardiomyopathy (oHCM) using myocardial work analysis, and explore its role in myocardia...

Epicardial Lead Dysfunction in a Patient With Mechanical Tricuspid Valve-A Challenging Complication.

Complete atrioventricular block after mechanical tricuspid valve replacement represents a challenging pacing scenario because transvalvular right ventricular lead placement is contraindicated. We repo...