Heart failure is an increasingly common comorbidity among people with HIV infection, complicating care and heightening the vulnerability of this population to social adversity (SA). However, the impac...
Heart failure is an increasingly common comorbidity among people with HIV infection, complicating care and heightening the vulnerability of this population to social adversity (SA). However, the impac...
Individuals of African ancestry are underrepresented in genetic studies, contributing to disproportionately higher rates of variants of uncertain significance (VUS) and fewer actionable results in gen...
Familial hypercholesterolemia (FH) is an inherited disorder characterized by lifelong elevated LDL-C (low-density lipoprotein cholesterol) and increased risk for premature myocardial infarction. FH re...
Cell size control emerges from the vein-dependent coordinated divisions of distinct cell groups in Drosophila wing.
During morphogenesis, cell divisions are precisely regulated in space and time. The biological objectives achieved by such regulation are not fully understood. Here, by applying a newly developed line...
The people behind the papers - Zhainib Amir-Ugokwe and Kristy Red-Horse.
During human vascular development and regeneration, arterial cells can be made from both mesodermal and venous cells. Whilst in vitro human models of mesodermal to arterial conversion have been establ...
[Research progress of lymphaticovenous anastomosis in treatment of severe extremity trauma].
OBJECTIVE: To review the research progress of lymphaticovenous anastomosis (LVA) in the treatment of severe extremity trauma and prospect its clinical application prospects. METHODS: Based on the exis...
Coronary Artery Calcium Score - Practical Considerations for Underwriting.
This brief practical review explores the fundamentals of coronary artery calcium score testing, its role in cardiovascular risk stratification, and how it can empower underwriting CV risks with greate...
[Effect of miR-155-5p regulating the TLR4/MAPK/NF-κB pathway on inflammatory response, coronary artery lesion and immune function in mice with Kawasaki disease].
OBJECTIVES: To investigate the effect of miR-155-5p regulation of the TLR4/MAPK/NF-κB pathway on inflammatory response, coronary artery lesion, and immune function in mice with Kawasaki disease (KD). ...
Determinants of systolic murmurs without significant valvular heart disease in an unselected Norwegian adult population: the Tromsø Study.
BACKGROUND: Systolic murmurs are common in adults without significant valvular heart disease (VHD) and are more prevalent in women than in men, but the determinants of murmur audibility remain unclear...
Myocardial fibrosis and viability: the role of imaging and biomarkers in patients with chronic total occlusion on coronary angiography.
In patients with chronic total occlusion on coronary angiography, myocardial viability assessment is an essential tool in guiding treatment decisions, especially revascularization. Current non-invasiv...
Effect of Ashwagandha (Withania somnifera) on cardiac aquaporins in adolescent rats under a chronic unpredictable mild stress model.
Adolescent depression is a prevalent and serious mental health issue that can negatively impact multiple organ systems, including the cardiovascular system. This study investigates the effects of chro...
Comparison of endovascular procedures of the lower extremities and iliac arteries with and without navigation assistance Vascular Navigation PAD: study protocol for a prospective multicenter randomized clinical trial.
BACKGROUND: Endovascular procedures using a mobile C-arm are commonly performed in patients with peripheral artery disease. During these procedures, digital subtraction angiography (DSA) requires intr...
Concurrent thyroid ima artery, high-riding brachiocephalic trunk, and supreme intercostal artery in thoracic vertebral artery configuration: a computed tomography angiography case report.
PURPOSE: To report a cluster of five concurrent cervical vascular variants identified on computed tomography angiography (CTA), including a thyroid ima artery (TIA) from a high-riding brachiocephalic ...
Development and application of a quantitative physicochemical model of P-gp substrate specificity.
Active transport of small molecules out of the cells mediated by efflux pumps of the ABC superfamily is an important biochemical phenomenon precluding delivery of drug molecules to the site of action,...
Atypical variants of the cerebral arterial circle beyond the Lazorthes classification: a retrospective morphologic and neuroradiologic study.
PURPOSE: To characterize atypical variants of the cerebral arterial circle that fall outside the Lazorthes classification and to interpret them in a contemporary neuroradiologic framework. METHODS: Th...
Anatomical characteristics and coordinate-based mapping of neurovascular structures within the ankle flexor retinaculum in Vietnamese cadavers.
PURPOSE: This study aimed to characterize the anatomical features of the ankle flexor retinaculum and to provide a coordinate-based anatomical data on tibial nerve and posterior tibial artery branchin...
Chronotherapy to reinforce circadian rhythms improves poststroke outcomes and glymphatic function in mice.
Stroke remains a leading cause of morbidity and mortality worldwide, with few effective interventions to promote recovery. Targeting circadian timing and glymphatic function may represent viable thera...
Clinical Case of Inferior Vena Cava Leiomyoma in a Patient with Thrombocytopenia.
Primary leiomyomas of the vascular system, particularly of the inferior vena cava (IVC), are extremely rare benign vascular tumors, which, due to their extraluminal growth, can mimic tumors of the adj...
[Rheumatoid nodule in the myocardium as part of the chain in a clinical detective. Case report].
The article describes a clinical case of a patient, at first glance healthy from the cardiovascular side, whose only complaint was ventricular extrasystole during exacerbations of arthritis. A typical...
From Leaky Gut to a Vulnerable Brain: Obesity-Associated Gut Barrier Failure in Colorectal Cancer and Cognitive Dysfunction.
Obesity is a major risk factor for colorectal cancer (CRC) and is increasingly recognized as a contributor to cancer-related cognitive impairment; however, the mechanistic pathways linking metabolic d...