Although transcatheter mitral valve-in-valve replacement (mViV) is safe, long-term outcomes compared with reoperative surgical mitral valve replacement (rSMVR) remains unknown. This study compared lon...
Although transcatheter mitral valve-in-valve replacement (mViV) is safe, long-term outcomes compared with reoperative surgical mitral valve replacement (rSMVR) remains unknown. This study compared lon...
This study aimed to evaluate the impact of proximal versus distal aortic clamping during thoracoabdominal aortic aneurysm (TAAA) repair, focusing on the incidence and predictors of left recurrent lary...
The objective of this secondary analysis was to examine the impact of two perfusion modalities on S100B levels and neural injury outcomes in congenital heart surgery patients undergoing cardiopulmonar...
Surgical left atrial appendage occlusion (sLAAO) is known to prevent strokes in patients with atrial fibrillation (AF). However, for AF patients on long-term anticoagulation (AC) little is known regar...
Management of atrial fibrillation (AF) at the time of coronary artery bypass grafting (CABG) is a Class 1 recommendation. This study evaluated trends in AF management and their association with long-t...
Pulsed field ablation (PFA) is emerging as alternative to thermal ablation for pulmonary vein isolation (PVI) in atrial fibrillation, though PFA-specific complications have arisen. This review provide...
Nanosecond pulse field ablation (nanoPFA) is an emerging nonthermal modality that may reduce muscle contractions and enable atrial fibrillation (AF) ablation under conscious sedation.
Early quantitative stress-perfusion cardiac magnetic resonance reveals perfusion abnormalities consistent with coronary microvascular dysfunction in MINOCA patients with otherwise normal cardiac magnetic resonance findings.
Coronary microvascular dysfunction (CMD) is a proposed contributor to myocardial infarction with non-obstructive coronary arteries (MINOCA), but the value of early quantitative stress-perfusion CMR (Q...
Intravenous Exposure to Amino-polystyrene Induces Excessive Autophagy and Apoptosis in Myocardium Through ROS Driven PI3K/AKT/mTOR Axis.
Polystyrene (PS) is a pervasive plastic whose threat to human health is growing, yet its cardiotoxicity, particularly under clinically relevant exposure scenarios, remains poorly understood. This stud...
The Woodpecker variable-speed drilling protocol for robot-assisted subaxial cervical pedicle screw placement: technique and a consecutive series of 1027 screws.
Published descriptions of robot-assisted cervical pedicle screw placement remain limited, particularly for subaxial screws and for workflows integrating positioning, registration, and drilling. Small ...
The diagnostic accuracy of left ventricular ejection fraction assessment between visual and artificial intelligence-based algorithms on bedside ultrasound.
BACKGROUND: Focused cardiac ultrasound (FoCUS) has become the standard of care for bedside assessments of cardiac function. With the integration of artificial intelligence (AI), there is limited evide...
Polygonum cuspidatum Exosome-Like Nanovesicles Alleviate Hypoxic Pulmonary Hypertension by Stabilizing PON1 to Inhibit MAPK-Mediated PASMC Phenotypic Switching.
Hypoxic pulmonary hypertension (HPH) is characterized by excessive proliferation of pulmonary vascular cells, ultimately resulting in right heart failure and death. Although resveratrol, an active com...
Right atrial thrombus and pulmonary embolism one year after ventricular septal defect patch repair: successful surgical management of a complicated case.
BACKGROUND: Right heart thrombi are rare but life-threatening, with particularly high mortality when accompanied by pulmonary embolism (PE). Cardiac surgery may predispose to in-situ thrombus formatio...
Promoting Effect of (+)-Borneol on Alzheimer's Disease Treatment in APP Transgenic Zebrafish and Its Blood-Brain Barrier Permeation Mechanism.
( +)-Borneol (Bor) has been shown to enhance drug penetration across the blood-brain barrier (BBB); yet its mechanisms of action and adjuvant effects on Alzheimer's disease (AD) drugs remain insuffici...
Cottonseed Oil Attenuates Traumatic Brain Injury by Inhibiting AKT/GSK-3β-mediated Neuroinflammatory Responses.
Traumatic brain injury (TBI) is a major cause of long-term neurological disability worldwide, and effective therapeutic strategies remain limited. Cottonseed oil (CSO), a plant-derived oil rich in pol...
Neuro-immune crosstalk in lung cancer brain metastasis: mechanisms, therapeutic targets, and translational opportunities.
Brain metastasis remains one of the most devastating complications of lung cancer, contributing to poor prognosis and limited therapeutic efficacy. Increasing evidence suggests that the development an...
Advances in ferroptosis and cuproptosis: implications for spinal cord injury.
Spinal cord injury (SCI) is characterized by multifaceted pathophysiological cascade encompassing neuron necrosis, inflammatory responses, glial scar deposition, and impediments to axon regeneration. ...
Predictive value of early postoperative hemodynamic parameters of Rex shunt graft for graft thrombosis in children with cavernous transformation of the portal vein.
OBJECTIVE: To investigate the predictive value of early hemodynamic parameters within Rex graft for postoperative graft thrombosis in children with cavernous transformation of the portal vein (CTPV). ...
Viscosity matters: OCTA assessment of retinal microcirculation under silicone oil tamponade.
PURPOSE: This retrospective observational cohort study utilized in situ optical coherence tomography angiography (OCTA) to directly compare the early retinal and choroidal microvascular effects of 100...