Electrophysiological Insights in a Successful Cavotricuspid Isthmus Ablation of an Atypical Denovo Single-Loop Clockwise Epicardial Biatrial Flutter.

Biatrial macro-reentrant tachycardias are rare in patients without prior atrial intervention and often pose diagnostic and therapeutic challenges. We present a case of de novo single-loop biatrial flu...

Successful Epicardial Ablation of a Right Infero-paraseptal Accessory Pathway Presenting as Ventricular Fibrillation.

A 22-year-old man presented with aborted sudden cardiac arrest due to ventricular fibrillation and recurrent tachyarrhythmia related to a right inferoparaseptal accessory pathway. A previous electroph...

High-Protein Diet Ameliorates Cardiomyopathy in a Cardiac-Specific AGL Knockout Mouse Model: Association With Upregulated Hepatic Gluconeogenesis.

Glycogen storage disease type IIIa (GSDIIIa) causes progressive cardiomyopathy, and current high-fat dietary strategies lack consensus regarding long-term cardiovascular safety. We evaluated the effic...

Proteomic Remodeling in the Failing Left Ventricle Adapting to Dyssynchrony.

PURPOSE: In heart failure, dyssynchrony is associated with accelerated cardiac remodeling and a worse prognosis. Both restored with resynchronization. We have previously developed a mouse model of dys...

Computed Tomography-Based Anatomical and Morphometric Analysis of the Left and Right Gastric Arteries in a Vietnamese Population.

Anatomical variations of the left gastric artery (LGA) and right gastric artery (RGA) are clinically relevant for gastric surgery and endovascular interventions. This study aimed to characterize the o...

Chronic kidney disease‑associated encephalopathy: Clinical features, pathomechanisms and emerging therapeutic strategies (Review).

Chronic kidney disease (CKD) is a progressive disorder whose systemic effects extend to the central nervous system, leading to CKD‑associated encephalopathy. Epidemiological data indicate that the pre...

Impact of Regional Hepatic Immunosuppression With Budesonide on Bacterial Elimination in Porcine Abdominal Sepsis.

INTRODUCTION: The liver is essential for bacterial elimination, preventing intestinal bacteria from entering the systemic circulation, and for producing inflammatory cytokines. Glucocorticoids have be...

Concurrent Four-Dimensional Dynamic MRA and Perfusion Imaging Using Dual-Module Arterial Spin Labeling MRI With Stack-Of-Stars Golden-Angle Radial Acquisition.

Arterial spin labeling (ASL) has been used for perfusion imaging and non-contrast enhanced dynamic MR angiography (MRA), and both have become favorable for clinical diagnosis and treatment planning of...

VesMamba: Vessel Morphology-Enhanced State Space Model for Cerebrovascular Delineation.

Accurate delineation of cerebrovascular structures from Time-Of-Flight Magnetic Resonance Angiography (TOF-MRA) and Computed Tomography Angiography (CTA) is essential for the clinical diagnosis and tr...

PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes.

Prolonged survival of patients with cancer has increased the need to address chemotherapy‑related cardiovascular complications. Doxorubicin (DOX), a widely used anthracycline, is associated with dose‑...

In Vivo Ultrasound Characterization of the Tibial Nerve at the Supramalleolar Region.

BACKGROUND: Accurate knowledge of the supramalleolar anatomy of the tibial nerve is essential for safe ultrasound-guided procedures and proximal nerve interventions in the foot and ankle. However, qua...

Study on retinal pharmacokinetic characteristics and precision drug administration strategy in patients with fundus diseases.

BACKGROUND: Fundus diseases are major causes of irreversible visual impairment. Retinal pharmacokinetic behavior may differ between diabetic retinopathy (DR) and age-related macular degeneration (AMD)...

Jianxin granules enhance autophagic flux and reduce apoptosis in heart failure via mTOR pathway: A preclinical investigation.

BACKGROUND: Heart failure (HF) is a leading cardiovascular disease worldwide. Jianxin Granule, a traditional Chinese medicine formula, has been clinically shown to improve cardiac function, yet its mo...

Correlation study of serum vitamin K and Gas6 levels with aortic arch calcification and left ventricular hypertrophy in maintenance hemodialysis patients.

BACKGROUND: Cardiovascular disease is the leading cause of death among MHD patients, with aortic arch calcification and left ventricular hypertrophy as common complications. The role of vitamin K-depe...

Endothelial dysfunction: A central mechanism linking autosomal dominant polycystic kidney disease and intracranial aneurysms (Review).

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disorder and is characterized by the progressive development of multiple bilateral renal cysts and the deterio...

Lecture-First Versus Practical-First Teaching Strategies in Cardiovascular Ultrasound Education: A Randomized Comparison of Undergraduate Performance.

Cardiovascular ultrasound is an operator-dependent modality that requires careful sequencing of the theoretical and practical training to optimize skills acquisition. This study compares lecture-first...

There is ongoing debate regarding the optimal multimodal treatment for patients with resectable locally advanced esophageal adenocarcinoma, with the recent ESOPEC trial suggesting perioperative chemot...

To develop a novel wearables-based sleep index that can quantify sleep disruption after lung resection and to apply machine learning analysis to these indices to identify patients exhibiting distinct ...