The Use of Ambulatory Blood Pressure Monitoring in Pediatric Heart Transplant Recipients.
BACKGROUND: Ambulatory blood pressure monitoring (ABPM) is the gold-standard non-invasive test for diagnosing arterial hypertension; however, it remains understudied in pediatric heart transplant reci...
Impact of prenatal maternal LDH levels on adverse pregnancy outcomes in women with hypertensive disorders during pregnancy.
OBJECTIVE: This study aimed to evaluate the association between maternal serum lactate dehydrogenase (LDH) levels and adverse pregnancy outcomes in women with hypertensive disorders of pregnancy (HDP)...
Long-Term Safety and Renal Outcomes of Semaglutide in Non-Diabetic Obesity with Chronic Kidney Disease or Hypertension: A Systematic Review and Meta-Analysis.
BACKGROUND: Semaglutide, a GLP-1 receptor agonist, has demonstrated metabolic and renal benefits in diabetic populations. However, its efficacy and safety in non-diabetic individuals with obesity and ...
Sociodemographic determinants of Pulmonary Hypertension in a Tertiary Care Hospital in Southern India.
BACKGROUND: Pulmonary hypertension (PH) is a progressive disorder with significant morbidity and mortality. Limited data exist on the demographics, echocardiographic profile, and quality of life of PH...
Hypertension-Mediated Organ Damage: Pathophysiological Mechanisms, Clinical Consequences, and Implications for Early Risk Stratification.
Hypertension-mediated organ damage (HMOD) represents a critical and dynamic stage on the cardiovascular continuum, serving as the primary mechanistic link between sustained arterial pressure elevation...
What does it mean to win? Interpreting hierarchical kidney outcomes in hypertension trials.
Hierarchical composite kidney outcomes analyzed using win statistics prioritize important events while avoiding some limitations of traditional composite end points. Liu et al. apply this approach to ...
Long-term Complications of Pulmonary Embolism: Which Is the Optimal Follow-Up?
Pulmonary embolism (PE) is associated with substantial long-term morbidity that extends past initial diagnosis. Patients diagnosed with PE face risks of chronic thromboembolic pulmonary hypertension, ...
Recent Advances in Pulmonary Hypertension Management.
Significant progress has been made in the management of pulmonary hypertension (PH), and especially pulmonary arterial hypertnesion (PAH), over the last 3 decades. Recent advances in the diagnosis, ri...
The Role of Machine Learning and Artificial Intelligence in Drug Discovery and Clinical Care of Pulmonary Hypertension.
Pulmonary hypertension (PH) is a severe and oftentimes fatal disease with a high degree of clinical variability. Its complexity necessitates a multifaceted approach, with clinical and prognostic resul...
Portopulmonary Hypertension: Current Perspectives.
Portopulmonary hypertension (PoPH) is a form of pulmonary arterial hypertension in the setting of cirrhotic or noncirrhotic portal hypertension. It is a significant complication affecting approximatel...
Exercise Training and Cardiac Rehabilitation in Chronic Thromboembolic Pulmonary Hypertension.
Patients with chronic thromboembolic pulmonary hypertension (CTEPH) were traditionally advised against exercise training, based on unsubstantiated concerns that exercise-induced increases in pulmonary...
Long-term Complications of Venous Thromboembolism: A Practical Guide.
Venous thromboembolism (VTE), comprising deep vein thrombosis (DVT) of the lower limbs and pulmonary embolism (PE), is associated with long-term functional impairment comparable to that seen after acu...
Advances in the Diagnosis of Chronic Thromboembolic Pulmonary Hypertension.
Chronic thromboembolic pulmonary hypertension (CTEPH) refers to precapillary pulmonary hypertension. Its diagnosis is rising since the pathophysiology is better understood and screening is more rigoro...
Pulmonary Hypertension: From Molecular Pathways to Patient Care.
Pulmonary hypertension (PH) is a heterogeneous condition defined by an increase in mean pulmonary arterial pressure over 20 mm Hg diagnosed through right heart catheterization. Its global prevalence i...
PROSTACYCLIN ANALOGS AND DIABETIC RETINOPATHY OUTCOMES IN PATIENTS WITH PULMONARY HYPERTENSION : A Cohort Analysis.
PURPOSE: The aim of this study was to evaluate the association between prostacyclin analog (PCA) therapy and the long-term incidence of diabetic retinopathy (DR) in patients with diabetes and pulmonar...
Prevalence and Correlates of Erectile Dysfunction: A Comparative Study of Adult Hypertensive Patients in an Outpatient Clinic, South East Nigeria.
BACKGROUND: There has been an increase in the prevalence of erectile dysfunction (ED) in the general population especially among hypertensive patients. This seems to be neglected problem in low-income...
Prevalence of (Pre)Hypertension and Correlations between Blood Pressures and Obesity in a Lean Population of Adults from the Old Eastern Region of Nigeria.
Hypertension is a prevalent disease globally and its prevalence is rising in sub-Saharan Africa. Urban-rural differences in the prevalence of hypertension are under-reported in Nigeria. Though hyperte...
Compensatory kidney enlargement and blood pressure patterns in children with a solitary functioning kidney.
BACKGROUND: Children with a solitary functioning kidney (SFK) are at risk for hypertension and kidney injury despite compensatory renal growth. However, the relationship between compensatory enlargeme...
Evaluation of the Molecular Docking of Potential Targets and the Time-Dependent Myocardial Effects of Omeprazole in Normotensive and Spontaneously Hypertensive Rats Subjected to Cardiac Ischemia and Reperfusion.
Proton pump inhibitors (PPIs) are widely prescribed for acid-related disorders and are generally considered safe for short-term use. However, increasing experimental and clinical evidence suggests pot...
Prevalence of erectile dysfunction and its associated factors among hypertensive men in Africa: a systematic review and meta-analysis.
BACKGROUND: Endothelial dysfunction and arterial stiffness are key underlying mechanisms that contribute to erectile dysfunction (ED), a common and often underdiagnosed condition among men with hypert...