[Posterior Reversible Encephalopathy Syndrome in a Patient with Chronic Kidney Disease on Hemodialysis and Refractory Hypertension: Case Report].

Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological entity characterized by an acute or subacute neurological onset, typically reversible within a few days following the rem...

Patient Empowerment and Digital Health Readiness for Diabetes and Hypertension Care in Rwanda.

Patient empowerment remains a critical component in the management of non-communicable diseases, particularly in low-resource settings where health system constraints limit continuity of care. Diabete...

Impact of Inhalation Sedation on Cardiovascular Haemodynamics in Hypertensive Patients Requiring Dental Treatment: A Clinical Observational Study.

BACKGROUND: Several research studies reported the anxiolytic and analgesic properties of nitrous oxide sedation, as well as its effectiveness in facilitating dental procedures for anxious populations,...

Updates in the Diagnosis and Management of Hypertension: A Review of Recent Guidelines.

Hypertension is one of the leading contributors to global cardiovascular morbidity and mortality. Recent updates to major international guidelines have introduced changes in diagnostic thresholds, ris...

Serum Pharmacochemistry-Guided DARTS-MS Profiling Reveals Potential Mechanisms of Caragana jubata Against Hypoxic Pulmonary Hypertension.

Hypoxic pulmonary hypertension (HPH) is a progressive vascular disease characterized by an abnormal increase in pulmonary arterial pressure resulting from pulmonary vasoconstriction and pulmonary vasc...

Dietary Determinants of Mental Well-Being Among Cardiometabolic High-Risk Adults in Hungary.

Background: Mental well-being is an important yet often overlooked component of cardiometabolic health. Dietary habits may influence psychological outcomes, but evidence among high-risk populations in...

Bibliometric and Two-Sample Mendelian Randomization Analyses of the Causal Relationship Between Hypertension and Erectile Dysfunction.

Hypertension (HT)-related erectile dysfunction (ED), a condition secondary to HT, is characterized by a persistent inability to achieve or maintain an erection sufficient for satisfactory sexual perfo...

Machine learning-based early kidney stone risk classification in diabetic-hypertensive patients using obesity composite indices.

Kidney stone disease (KSD) is increasingly prevalent among patients with diabetes mellitus and hypertension. Obesity-related metabolic abnormalities may be associated with stone formation, yet their c...

Risk factors for unanticipated hypertension during emergence from general anesthesia in elderly surgical patients: A retrospective cohort analysis.

Unanticipated hypertension in the postanesthesia care unit (PACU) refers to acute blood pressure elevation in patients whose preoperative baseline blood pressure was normal, possibly resulting in adve...

Association between weekend catch-up sleep and metabolic syndrome: A cross-sectional study.

The association between weekend catch-up sleep (WCS) and the prevalence of metabolic syndrome (MetS) remains controversial. This study aimed to investigate the association between WCS and MetS. This c...

Phytochemical Characterization and Immunometabolic Modulation by Mangifera indica (Mahajanaka) Pulp Extract in Diabetic and Hypertensive Rat Models.

Mango (Mangifera indica L.) pulp contains bioactive compounds with potential therapeutic effects against metabolic and immune-related disorders. However, the integrated effects of mango pulp extract o...

A Dysbiosis-Urolithin A Depletion-Low 6-Sulfatoxymelatonin Triad as a Composite Biomarker Framework Across Age-Related Vascular and Malignant Disease States.

Urolithin A (UA) is a gut microbiota-derived postbiotic generated from dietary ellagitannins, while urinary 6-sulfatoxymelatonin (6-SMT) is a surrogate marker of nocturnal melatonin output. We explore...

Primary aldosteronism.

Primary aldosteronism (PA) results from excessive aldosterone production by one or both adrenal glands and is an important cause of hypertension, leading to increased cardiovascular and renal morbidit...

Gastrodin Ameliorates Blood Pressure by Targeting the PPAR-γ/NF-κB/NLRP3 Signaling Axis in the Hypothalamic Paraventricular Nucleus.

Hypertension increases the risk for cardiovascular and cerebrovascular diseases and both its preventive and current therapeutics measures require extensive investigations. Despite that Gastrodin, a ne...

Contributions of preeclampsia to preterm delivery: a hypothetical interventional cohort study using incremental propensity scores.

BACKGROUND: Preeclampsia remains a leading cause of preterm delivery (PTD). Conventional average causal effect estimands may not always be perfectly suited for assessing preeclampsia's contributions b...

Age at menarche and adverse pregnancy and perinatal outcomes: triangulating evidence from multivariable and Mendelian randomization analyses.

BACKGROUND: Observational studies have suggested that a younger age at menarche is associated with increased risks of adverse pregnancy and perinatal outcomes. However, it is unclear whether these rel...

[PRDX1 attenuates hypertensive endothelial dysfunction by inhibiting mTOR/p70S6K signaling].

Objective: To explore the role and molecular mechanism of peroxiredoxin 1 (PRDX1) in hypertension-induced endothelial dysfunction. Methods: (1) Bioinformatics analysis: A total of 40 C57BL/6J mice age...

TRPV1 Activation Is Associated with Improved Mitochondrial Function and Cardioprotection in Experimental Hypertension.

Background: Systemic arterial hypertension (SAH) induced by Nω-nitro-L-arginine methyl ester (L-NAME) is a well-established model characterized by nitric oxide (NO●) synthase inhibition and vascular d...

Synergistic Effect of Hypertension and Smoking on Ischemic Stroke Risk: A Case-Control Study With Additive and Multiplicative Interaction Analysis.

Ischemic stroke remains a leading cause of death and disability worldwide. This single-center retrospective case-control study evaluated the independent and interactive effects of smoking, alcohol con...

Intersection of Pediatric Hypertension and Cardiovascular-Kidney-Metabolic Disease.

PURPOSE OF REVIEW: The purpose of this review is to describe the intersection between pediatric hypertension and advancing stages of cardiovascular, kidney metabolic syndrome in children and adolescen...