[Research advances in the molecular mechanisms of microRNA-mediated macrophage lipid homeostasis and foam cell formation].
The progression of atherosclerosis (AS) is intrinsically associated with dysregulated lipid metabolism in macrophages, leading to the formation of foam cells. MicroRNA (miRNA) finely regulates the exp...
Heart Failure Medication Withdrawal in Patients With Improved Cardiac Function After Atrial Fibrillation Ablation: The DEFINITION-AF Pilot Randomized Clinical Trial.
IMPORTANCE: Withdrawal of guideline-directed medical therapy (GDMT) for heart failure (HF) is common after atrial fibrillation (AF) catheter ablation and recovery of cardiac function, but safety remai...
The Right Ventricle in Cardiac Critical Care: Pathophysiology, Evaluation and Management.
The right ventricle (RV) is a primary determinant of outcomes in cardiac critical care. RV dysfunction independently predicts morbidity and mortality in conditions such as acute coronary syndromes, pu...
[Inflammatory Heart Disease: The Role of Multimodality Cardiac Imaging in Myocarditis and Pericarditis].
Myocarditis and pericarditis represent a broad spectrum of inflammatory heart diseases and are important differential diagnoses in patients presenting with chest pain, heart failure, or arrhythmias. D...
[Multimodal imaging in cardiac amyloidosis and cardiac sarcoidosis].
Cardiac amyloidosis and cardiac sarcoidosis can be classified as infiltrative cardiomyopathies. Although the aetiology and underlying pathophysiology of these two conditions differ substantially, imag...
[What do Swiss doctors think about cardiovascular risk factors and guidelines?].
While cardiovascular diseases are highly prevalent, their risk factors, especially hyperlipidemia, hypertension, and diabetes mellitus, are also very treatable with medication. Nevertheless, only a co...
[Coronary angiography: From cardiac catheterization to advanced interventional cardiovascular imaging].
Coronary angiography has evolved from the first cardiac catheterization performed by Werner Forssmann into a highly precise imaging modality of the coronary arteries. Modern techniques such as intrava...
Sex-Based Disparities in Health Care Access and Utilization Among Patients With Atrial Fibrillation.
IMPORTANCE: Females with atrial fibrillation (AF) experience a higher risk of stroke, myocardial infarction, and mortality than males with AF. Theories suggest that sex-based differences in hormonal, ...
Verbessert die Apple Watch die Früherkennung von Vorhofflimmern? – Die EQUAL-Studie.
TITEL: Verbessert die Apple Watch die Früherkennung von Vorhofflimmern? – Die EQUAL-Studie.
[Athlete's heart: role of cardiac imaging in the prevention of sudden cardiac death].
Sudden cardiac death (SCD) in athletes is usually the result of an undetected underlying heart disease, with physical exertion acting as the trigger. Commotio cordis is a rare cause of SCD. In young a...
The "Brain's Traffic Map" Reveals Neural Pathways Linked to Coronary Microvascular Dysfunction in Women.
BACKGROUND: The brain-heart axis is central to vascular health, yet no imaging biomarkers capture integrated dysfunction across neural and coronary microvascular networks. Although coronary microvascu...
Analysis of Myocardial Textures in Relation to Nicotine Abuse Using Radiomics in Cardiac PCCT.
Background/Objectives: Photon-counting computed tomography (PCCT) combined with radiomics enables advanced myocardial tissue characterization beyond conventional imaging. This study investigated wheth...
Oral Health and Cardiovascular Disease Among Hypertensive Medicated Adults With Uncontrolled Blood Pressure.
Oral diseases and masticatory dysfunction are more prevalent in hypertensive patients and may hinder blood pressure (BP) control during pharmacological treatment. However, the effect of the oral funct...
HAT-ECG: Hybrid autoencoder-transformer architecture for ECG arrhythmia classification.
Accurate and efficient analysis of electrocardiogram (ECG) signals is essential for early detection of cardiac arrhythmias. However, many deep learning models suffer from limited generalization to uns...
Evaluate the Prognostic Value of serumγKlotho on Long-Term Prognosis of Patients With Multivessel Coronary Artery Disease and Establish a Prognostic Model.
OBJECTIVE: This study was aimed at analyzing the correlation of serum γKlotho with the long-term prognosis of multivessel coronary artery disease (MVD) and develop a predictive model to predict an acc...
Application of LLMs in CAD-RADS Classification and Patient Management.
PURPOSE: To evaluate the capability of four publicly available Large language models (LLMs) to assign Coronary Artery Disease-Reporting and Data System (CAD-RADS) scores and provide patient management...
Transient outward K+ current inhibition suppresses early afterdepolarizations and ventricular arrhythmias via trajectory displacement away from an oscillatory regime.
Excitable biological systems can undergo abrupt transitions from stable rhythmic activity to pathological oscillations through subtle changes in slow-fast dynamical structure. In cardiac ventricular m...
Neighborhood Disinvestment and Racial Disparities in Early Hypertension Onset Among Women.
IMPORTANCE: Although Black women are known to have higher hypertension rates than White women, longitudinal investigations of racial disparities in early hypertension onset and the role of neighborhoo...
Therapeutic Plasma Exchange in the Elderly: Rare Indications but Good Tolerability.
Therapeutic plasma exchange (TPE) is used for a wide range of indications and is associated with well-described adverse events. However, no study has specifically focused on tolerance in elderly patie...
Retinal Ischemic Perivascular Lesions in Pulmonary Hypertension: Retinal Biomarkers Informing Systemic Microvascular Dysfunction.
PURPOSE: Retinal ischemic perivascular lesions (RIPLs), seen on optical coherence tomography (OCT) as localized retinal changes, are markers of subclinical retinal infarcts. RIPLs are linked to system...