A Clinical Prediction Model for Selective NT-proBNP Testing in Hypertension.

N-terminal pro-B-type natriuretic peptide (NT-proBNP) testing is recommended for pre-heart failure (pre-HF) screening. However, universal NT-proBNP testing is infeasible and inefficient. We analyzed d...

Diuretic Intensity Score and Mortality in Hospitalized Heart Failure Patients: A Multicenter Propensity-Matched Analysis.

AIMS: To develop and evaluate a novel Diuretic Intensity Score (DIS) and investigate its relationship with mortality in hospitalized heart failure patients. METHODS: We analyzed propensity-matched dat...

Thorough QT/QTc Clinical Study to Evaluate the Effect of Remdesivir on Cardiac Repolarization in Healthy Participants.

QT interval prolongation associated with drug administration is an important consideration in drug development. Patients with COVID-19 are at increased risk for cardiac complications, and QT interval ...

Network Pharmacology Reveals the Mechanism of Sini Decoction Against Aconitum carmichaelii Debeaux-Induced Cardiotoxicity.

Sini Decoction (SND), particularly its components Zingiber officinale Roscoe and Glycyrrhiza uralensis Fisch, is traditionally used to mitigate the cardiotoxicity induced by Aconitum carmichaelii Debe...

Barium-associated intestinal ischemia complicated with massive hepatic portal venous gas: A successful survival case report.

Barium-associated intestinal ischemia is a rare but life-threatening complication following upper gastrointestinal barium contrast examinations, with an incidence of less than 0.01%. Hepatic portal ve...

Factors Associated With Evidence of Self-Measured Blood Pressure Adoption in an Urban Safety-Net Health System.

Uncontrolled hypertension is a leading cause of preventable cardiovascular mortality. Although self-measured blood pressure (SMBP) monitoring is recommended by evidence-based guidelines, adoption rema...

Iron deficiency and risk of acute kidney injury after TAVI: a machine learning analysis.

BACKGROUND: Transcatheter aortic valve implantation (TAVI) has become the preferred therapeutic option for patients with severe aortic stenosis (SAS) at high or intermediate surgical risk. Despite its...

Exploring the Association Between Mental Disorders and Various Arrhythmias via Mendelian Randomization Methods.

Major depression, bipolar disorder, and schizophrenia are common mental illnesses, and their potential association with arrhythmias has long been a focus of clinical and research interest. To explore ...

Does New Rapid Optical Coherence Tomography Angiography Acquisition Affect Image Quality in Healthy and Diseased Eyes?

PURPOSE: The purpose of this study was to compare standard 85 kilohertz (kHz) and newer high-speed 125 kHz optical coherence tomography angiography (OCTA) scanning modes in healthy and diseased eyes, ...

Beta-Blockers After Myocardial Infarction With Preserved and Mildly Reduced Ejection Fraction: A Meta-Analysis With Trial Sequential Analysis.

AIMS: We aimed to evaluate the efficacy of β-blockers after myocardial infarction (MI) across left ventricular ejection fraction (LVEF) strata and to assess the conclusiveness of the available evidenc...

Age-related arterial stiffness and cerebrovascular dysfunction in mice correlate with cognitive impairment but are not reduced with long-term ALT-711 treatment.

Age-related increases in large artery stiffness contribute to cerebrovascular dysfunction and cognitive impairment. Alagebrium Chloride (ALT-711) is a collagen crosslink breaker that reduces vascular ...

[Rehabilitation for coronary heart disease: the role of physical therapy and other members of the rehabilitation team].

In the context of tertiary prevention, cardiac and vascular rehabilitation is considered the most effective means of reducing mortality, morbidity, and disability among patients with coronary artery d...

[Nursing care throughout the coronary patient's treatment journey].

A major public health issue in France, coronary artery disease requires care that involves support at every stage of its progression. Working in intensive care, conventional cardiology, and post-hospi...

[The medical management of coronary artery disease].

The management of coronary artery disease rests on two main pillars: treating the consequences of myocardial ischemia and preventing cardiovascular risk factors. Angioplasty and thrombolysis are treat...

[Pathophysiology and screening for coronary artery disease].

Coronary artery disease exhibits significant pathophysiological differences between men and women. These differences account for atypical clinical presentations and delayed diagnosis. The European Soc...

[Coronary heart disease: public health challenges and strategies].

In France, a patient dies of a heart attack every fifteen minutes. How do coronary diseases affect public health? Since these conditions are linked to controllable risk factors, French health policies...

Adeno-Associated Virus Vector Mediated Gene Therapy: A Promising Approach to Transform Hypertrophic Cardiomyopathy Treatment.

Hypertrophic cardiomyopathy (HCM) is a genetically heterogeneous myocardial disease that usually arises from mutations in key sarcomeric proteins, particularly MYBPC3 and MYH7. Current pharmacological...

Prevalence and Severity of Coronary Artery Calcification Assessed by Low-Dose Computed Tomography in Individuals With Type 2 Diabetes With and Without Diabetic Foot: A Cross-Sectional Study.

BACKGROUND: To investigate whether diabetic foot (DF) is associated with a higher prevalence and severity of coronary artery calcification (CAC) in patients with type 2 diabetes (T2DM) using low-dose ...

Qualitative and Quantitative Assessment of Restored Capillary Perfusion on OCT Angiography in Diabetic Macular Ischemia.

PURPOSE: The purpose of this study was to investigate characteristics of restored capillary perfusion on optical coherence tomography angiography (OCTA) in diabetic retinopathy (DR). METHODS: We prosp...

Minimal Perceived Discomfort During Oscillometric Blood Pressure Measurement in Children: A Cross-Sectional Study With Implications for Systematic Screening.

Routine blood pressure measurement in children has been proposed for systematic screening, but concerns remain regarding potential harm, including procedural discomfort. This has not previously been s...