Abdominal fat thickness predicts the risk of pregnancy-associated hypertension: A prospective cohort study.

BACKGROUND AND OBJECTIVES: Pregnancy-associated hypertension (PAH) is a prevalent complication during pregnancy. Maternal obesity is a known risk factor for PAH. As nutrition is a key modifiable drive...

[Artificial intelligence in hypertension: where do we stand?].

Artificial intelligence (AI) is entering the study of hypertension, serving both primarily clinical purposes - to assist practicing physicians - and research objectives. Hypertension presents certain ...

Four-Chamber Deformation Remodeling and Atrial Fibrillation After Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy.

INTRODUCTION: Septal myectomy treats hypertrophic obstructive cardiomyopathy (HOCM), but its effect on myocardial deformation across cardiac chambers is incompletely defined. We evaluated chamber-spec...

Left Atrial Coupling Indexes as New Mortality Predictors in Chronic Chagas Disease.

PURPOSE: This study aimed to evaluate the all-cause mortality predictive value of left atrioventricular coupling indexes in patients with chronic Chagas disease (CD). METHODS: This single-center retro...

The Cavβ4 subunit of Cav1.2 channels antagonizes isoproterenol-induced hypertrophy in rat cardiac muscle cells by down-regulating miR-183-5p.

The Cavβ4 subunit of voltage-gated Cav1.2 channels regulates gene expression in neurons and cardiac cells. It increases the expression of interferon-β-related genes in H9c2 cardiomyocytes derived from...

Fetal Superior Mesenteric Artery Peak Systolic Velocity as a Marker of Prenatal Bowel Inflammation in Gastroschisis: A Case-Control Study.

OBJECTIVE: This study aimed to evaluate whether peak systolic velocity (PSV) in the fetal extra-abdominal superior mesenteric artery (SMA) is a useful prenatal marker of bowel inflammation in gastrosc...

Impact of the 2025 ASE Updated Recommendations on the Diagnosis of Left Ventricular Diastolic Dysfunction in Asymptomatic Elderly Inpatients With Preserved Ejection Fraction: A Multi-Center Retrospective Study.

BACKGROUND: Echocardiographic evaluation of left ventricular diastolic dysfunction (LVDD) remains ambiguous in asymptomatic elderly patients with preserved left ventricular ejection fraction (LVEF). T...

Mortality Trend in Patients With Heart Failure and Psychoactive Substance Abuse in the United States-Pre- and Post-COVID-19 Pandemic Perspective (1999-2023).

BACKGROUND: This study evaluates national trends in heart failure (HF) and psychoactive substance abuse-related mortality among adults aged 25 years and older in the United States (US) from 1999 to 20...

National Trends & Disparities in Ischemic Heart Disease & Cardiac Arrhythmias Related Mortality in the United States From 1999 to 2024: A CDC Wonder Analysis.

BACKGROUND: Ischemic heart disease and cardiac arrhythmias are major contributors to cardiovascular mortality in the United States. Understanding long-term national trends and demographic disparities ...

Pharmacological Insights and Clinical Challenges of Wenxin Keli in Arrhythmia Treatment.

Cardiac arrhythmias remain a leading cause of cardiovascular morbidity and mortality worldwide. Although conventional antiarrhythmic drugs are effective, their use is constrained by proarrhythmic risk...

Engineered exosomes improve myocardial cell membrane integrity and heart function in dystrophic cardiomyopathy.

BACKGROUND: Duchenne muscular dystrophy (DMD)-associated cardiomyopathy is a leading causes of premature death, yet treatment options remain limited. In this study, we developed the easily accessible ...

Morroniside Attenuates Doxorubicin-Induced Cardiotoxicity by Activating the PI3K/AKT/Nrf2/HO-1 Pathway to Inhibit Ferroptosis and Oxidative Stress.

Cardiotoxicity induced by doxorubicin (Dox) significantly contributes to increased mortality among cancer patients, yet available pharmacological interventions remain scarce. Recent studies suggest th...

Myocardial Lipid Metabolism Imbalance: The Pathological Core and Novel Diagnostic-Therapeutic Directions of Cardiovascular Diseases.

Cardiac lipid metabolism is fundamental to myocardial energy homeostasis, with fatty acid oxidation (FAO) supplying the majority of ATP in the healthy adult heart. This review synthesizes the core reg...

Preoperative MRI Intratumoral Heterogeneity Radiomics for Microvascular Invasion and Recurrence-Free Survival in HCC.

BACKGROUND AND AIMS: Microvascular invasion (MVI) is a major determinant of postoperative recurrence and poor prognosis in hepatocellular carcinoma (HCC), yet MVI cannot be reliably identified before ...

Association between the Atherogenic Index of Plasma and in-Hospital Mortality in Individuals with Sepsis.

PURPOSE: Numerous studies have shown that the atherogenic index of plasma (AIP) is a strong predictor of the risk of cardiovascular diseases (CVDs) and an independent predictor of cardiovascular event...

Clinical Applications of Cardiac Diffusion MRI: A Scoping Review.

Purpose To characterize the extent, clinical applications, and emerging trends of diffusion-weighted imaging (DWI) techniques in cardiac MRI using a scoping review of in vivo human studies. Materials ...

The Role of Preprocedural CT in Redo Transcatheter Aortic Valve Replacement: A Radiologist's Perspective.

As transcatheter aortic valve replacement (TAVR) has become a viable option across all surgical risk levels, younger patients are anticipated to outlive the durability of their index transcatheter hea...

General Hepatology Concerns for the Patient with Cholestatic Liver Disease.

This review provides a clinical summary of the extrahepatic manifestations of cholestatic liver disease that is important for the managing general hepatologist. Drawing on evidence from primary biliar...

Real-World Data-Driven Insights in Obesity: A Comparative Cross-Sectional Analysis of General Practice and a Specialized Obesity Clinic in Belgium-An IMI2 SOPHIA Study.

There is a lack of knowledge on the registration of body mass index (BMI) and prevalence of obesity-related complications in the Belgian healthcare system. We therefore evaluated these in Belgians liv...

Incidence and diagnostic yield of repeat imaging-based screening for hepatic arteriovenous malformations in patients with HHT.

BACKGROUND AND AIMS: Hepatic arteriovenous malformations (HAVMs) are a common visceral manifestation of hereditary hemorrhagic telangiectasia that can lead to heart failure and biliary ischemia. Curre...