The relative efficacy and safety of oral P2Y purinergic receptor 12 (P2Y12) inhibitors (clopidogrel, ticagrelor, or prasugrel) after percutaneous coronary intervention (PCI) are not well defined.
The relative efficacy and safety of oral P2Y purinergic receptor 12 (P2Y12) inhibitors (clopidogrel, ticagrelor, or prasugrel) after percutaneous coronary intervention (PCI) are not well defined.
Venous thromboembolism (VTE), which encompasses deep vein thrombosis and pulmonary embolism, is a frequent condition that can lead to significant morbidity and mortality; statins, monoclonal antibody ...
Coronary function testing (CFT) can be used to delineate the underlying mechanisms of chest pain in angina with nonobstructive coronary arteries (ANOCA). However, the association between overlapping A...
Calcium release deficiency syndrome (CRDS) is a recently described inherited arrhythmia caused by loss-of-function variants in the cardiac ryanodine receptor (RYR2). Diagnosis currently requires in vi...
Data regarding acute blood pressure (BP) drops during pulsed-field ablation (PFA) for pulmonary vein isolation (PVI) are limited.
Consensus documents classify cardiogenic shock (CS) centers on the basis of percutaneous coronary intervention (PCI), mechanical circulatory support (MCS), and cardiothoracic surgery (CTS) capabilitie...
Membrane Oxygenation Improves Functional Myocardial Preservation and Enables Colloid-Enriched Perfusion in the Langendorff Isolated Heart Model.
Background: The Langendorff isolated heart model remains one of the most widely used experimental platforms for cardiovascular research. However, conventional bubble oxygenation is associated with sev...
Murine Model for Selective Transection of Intestinal Autonomic Nerves.
Autonomic nerves comprise the sympathetic and parasympathetic systems, which act in a largely antagonistic manner to regulate diverse physiological functions. With growing interest in the roles of aut...
Cinematic Rendering of 3D Early and Late Gadolinium Enhancement Cardiac MRI: A Feasibility Demonstration.
Cinematic rendering (CR) is a physically based three-dimensional visualization technique that uses Monte Carlo path tracing with global illumination to generate photorealistic images from volumetric m...
The Dual Role of VEGF in Intracerebral Haemorrhage: From Pathological Mechanisms to Therapeutic Opportunities.
An intracerebral haemorrhage (ICH) is a general type of haemorrhage in the brain, which arises due to the rupture of cerebral blood vessels. Many molecules have been investigated for their potential a...
Routine external aortic compression versus no aortic compression in elective caesarean delivery to reduce blood loss: study protocol of a randomised controlled trial.
INTRODUCTION: External aortic compression is used to reduce excessive blood loss in childbirth. However, it has never been evaluated for the prevention of postpartum haemorrhage. This study aims to in...
Cardiopulmonary interactions during paediatric mechanical ventilation: protocol for a scoping review.
INTRODUCTION: The heart and lungs are closely linked anatomically and physiologically, sharing the thoracic cavity and jointly ensuring oxygenation and removal of carbon dioxide. With the introduction...
Metabolic Heterogeneity Across Heart Failure Subtypes Defined by Integrative Multi-Omics Analysis.
Heart failure (HF) is a heterogeneous syndrome with diverse etiologies, yet the metabolic determinants specific to its subtype remain unclear. We performed an integrative multi-omics analysis combinin...
Comparison of effectiveness and safety of different haemostatic materials in patients undergoing transradial coronary intervention and diagnosis: a protocol for systematic review and network meta-analysis.
INTRODUCTION: Effective compression haemostasis is essential after transradial coronary procedures. However, evidence directly comparing different haemostatic materials remains limited. This study aim...
Cardiovascular Nanomedicine: Breakthroughs in Therapy-Challenges in Safety and Cardiotoxic Risks: A Comprehensive Review of Inorganic Nanoparticles.
The unique physicochemical properties of nanoparticles (NPs) have facilitated the development of targeted therapies for cardiovascular diseases (CVDs). According to World Health Organization estimates...
Effects of Low-Intensity Aaerobic Training on Cardiac Dysfunction and Myocardial Fibrosis Induced by Doxorubicin in Wistar Rats.
Doxorubicin-induced cardiotoxicity is a major limitation in cancer therapy. Physical exercise has been proposed as a non-pharmacological strategy capable of mitigating these effects through cardiovasc...
Mechanics and mechanobiology of arterial development.
Arteries serve primarily a biomechanical function. Critical insight into arterial structure, properties, and function thus derives from knowledge of mechanosensitive gene expression, associated micros...
Intraoperative relationship between the retromandibular vein and the marginal mandibular branch of the facial nerve: a prospective surgical study and literature review.
PURPOSE: To prospectively evaluate the intraoperative relationship between the retromandibular vein (RMV) and the marginal mandibular branch (MMB) or inferior facial nerve division during parotidectom...