[A case of esophagoleft atrial fistula mixed with infective endocarditis].

该文报道1例老年女性患者，因鱼骨所致食管损伤继发食管-左心房瘘，合并缓症链球菌与热带念珠菌混合感染性心内膜炎。患者外院曾误诊为左心房血栓，经增强CT检查提示心腔积气，最终经左心房食管瘘修补术联合赘生物清除术得以确诊。该文围绕心腔积气的影像学预警价值、病原菌谱特点、长疗程抗感染与抗真菌策略、手术时机选择及围手术期多学科管理进行探讨。.

Immunometabolic Mechanisms of Coronary Microvascular Dysfunction in Coronary Artery Disease: The Role of Mitochondrial Stress, Endothelial Senescence, and Regulated Cell Death.

Chronic coronary syndromes (CCSs) are increasingly recognized as complex immunometabolic vascular disorders in which coronary microvascular dysfunction (CMD), persistent low-grade inflammation, oxidat...

Ductus arteriosus aneurysm in a neonate with inspiratory stridor.

BACKGROUND: Inspiratory stridor in neonates is typically attributable to laryngomalacia, vocal cord paralysis, or subglottic stenosis. Less commonly, vascular anomalies can cause inspiratory stridor. ...

Contemporary Outcomes of the Ross Procedure in Adults: Implications for Current Clinical Practice.

BACKGROUND: With renewed enthusiasm for the Ross procedure in adults in recent years, long-term data using contemporary techniques are needed. OBJECTIVES: The purpose of this study was to evaluate lon...

Chronic mesenteric ischaemia: an overlooked cause of unintentional weight loss.

Chronic mesenteric ischaemia (CMI) is a rare but potentially life-threatening condition, often underdiagnosed due to its vague and non-specific symptoms. We describe a patient who presented with progr...

Renal vein thrombosis as a reversible vascular renal complication of CLOVES syndrome: a case report.

PIK3CA-related overgrowth spectrum (PROS) comprises mosaic gain-of-function variants in PIK3CA that lead to segmental overgrowth and complex vascular malformations. Renal involvement has been inconsis...

Auriculotemporal nerve morphology revisited: a novel classification based on root pattern and arterial topography.

The auriculotemporal nerve (ATN), carrying both sensory and parasympathetic fibers, is a branch of the mandibular nerve (MN) and courses through the anatomically complex infratemporal fossa (ITF). Alo...

Zinc-binding protein metallothionein 3 protects vascular smooth muscle cells from ferroptosis via blocking lysosomal degradation of GPX4.

Aortic dissection (AD) is a life-threatening vascular emergency characterized by medial degeneration and vascular smooth muscle cell (VSMC) loss. Although disruption of zinc homeostasis has been repor...

Umbilical vein-ductus venosus angle: a novel ultrasound marker for predicting optimal umbilical venous catheter placement.

UNLABELLED: Umbilical venous catheterization is a common procedure performed in intensive care units. Point-of-care ultrasonography enables efficient vascular access and reliable assessment of cathete...

Integrated morphological analyses of Cladomorphus phyllinus and transcriptomic analysis of Cladomorphus trimariensis provide insights into the cardiac morphophysiology of stick insects (Phasmida: Phasmatidae).

The heart of Phasmida (stick insects) remains poorly understood, particularly regarding its overall physiology and associated cells. Here, we integrate the morphology of the heart and associated cells...

Endothelial KLF4 depletion drives age-related neurovascular dysfunction and neuropsychiatric impairment.

Deterioration of the blood-brain barrier (BBB), including impaired neurovascular uncoupling, contributes to cognitive decline in aging. The BBB is formed principally by brain microvascular endothelial...

Regulatory logic underlying neural crest contributions to the head versus the heart.

Neural crest cells exhibit axial-level-specific transcriptional programs, yet the regulatory mechanisms underlying their fate decisions remain unclear. Here, we investigate whether differential transc...

Coronary artery bypass grafting is a well-established, durable, and safe surgical intervention. However, coronary artery disease continues to progress after the procedure. Patients who have undergone ...

Randomized trials evaluating multiarterial grafting (MAG) vs single arterial grafting (SAG) during coronary artery bypass grafting (CABG) have not demonstrated a long-term survival benefit, whereas co...

Inhibition of proprotein convertase subtilisin/kexin type 9 (PCSK9) is an effective therapy for reducing low-density lipoprotein (LDL) cholesterol (LDL-C) in adults with hyperlipidemia, including hete...

Resources for observational comparative research have expanded enormously in recent years to include very large sources of granular, routinely collected health care data and modern statistical, epidem...

Metabolic remodeling, marked by maladaptive shifts in substrate use and energy production, is a hallmark of pathologic cardiac hypertrophy. Yet the mechanisms linking stress signaling to impaired myoc...

Lipoprotein(a) [Lp(a)] is a risk factor for coronary heart disease. Whether baseline Lp(a) identifies higher risk patients who derive more benefit from evolocumab is not established in a population wi...

Cardiac sarcoidosis (CS) is an enigmatic disorder characterized by unexplained patchy, sterile granulomas intermixed with preserved myocardium and fibrotic regions without granuloma. CS causes arrhyth...

Effects of Chronic Renal Insufficiency Combined with Atrial Fibrillation on Left Atrial Endothelial Function in a Beagle Model.

The co-occurrence of atrial fibrillation (AF) and renal insufficiency (RI) represents a clinically complex phenomenon with high prevalence. This study investigated the impact of chronic moderate RI co...