Percutaneous left atrial appendage closure following catheter ablation therapy of atrial fibrillation: outcomes stratified by bleeding risk - a sub-analysis of the OPTION study.

AIMS: Concerns have been raised over the safety and necessity of continuing oral anticoagulation (OAC) in patients following catheter ablation for atrial fibrillation (AF). OPTION demonstrated the saf...

Standardized End Point Definitions for Clinical Trials in Thoracic Aortic Repair: A Consensus Report From the ARCH-Academic Research Consortium.

Innovation in the treatment of ascending aorta and arch pathology with novel catheter-based and hybrid procedures has driven the need for a strategy to guide their safe application. The ARCH-ARC (Aort...

Extending the Reach of GLP-1 Receptor Agonists for Cardiovascular Risk Reduction.

Journal of the American College of Cardiology

SELECTIVE BRONCHIAL ARTERY CHEMOINFUSION IN NSCLC: CURRENT STATE OF REGIONAL THERAPY AND ITS ROLE IN MULTIMODAL APPROACHES.

UNLABELLED: Regional intra-arterial delivery of cytotoxic drugs into bronchial arteries (bronchial artery infusion - BAI; bronchial arterial chemoembolization - BACE; drug-eluting bead BACE - DEB-BACE...

ASSESSMENT OF VITEX AGNUS-COSTES PLANT EXTRACT ON THE HEART OF MICE EXPOSED TO OXIDATIVE STRESS.

Myocardial injury is largely the result of oxidative stress, which alters the structure and function of the heart's cardiomyaceous and conduction cells. The purpose of this investigation is to determi...

Adjunctive Cerebrolysin therapy following mechanical thrombectomy for acute basilar artery occlusion: a case report.

Basilar artery occlusion (BAO) is an uncommon yet devastating cause of posterior circulation stroke, frequently resulting in severe disability or death despite successful reperfusion. We describe a 67...

Diagnostic value of cervical vascular ultrasound combined with CT angiography in carotid artery plaque in patients with cerebral infarction.

OBJECTIVE: To clarify diagnostic value of cervical vascular ultrasound (CVUS) combined with CT angiography (CTA) in carotid artery plaque in patients with cerebral infarction. METHODS: A total of 110 ...

[Analysis of Risk Factors and Construction of Predictive Model for Iliac Vein Compression Syndrome Combined with Deep Vein Thrombosis of the Lower Extremities].

OBJECTIVE: To explore the risk factors of lower extremity deep vein thrombosis (DVT) in patients with iliac vein compression syndrome (IVCS) and to construct a risk prediction model. METHODS: A total ...

Hydatid Cyst of Right Atrium.

A 70-year-old male presented with dyspnea New York Heart Association (NYHA) class II since 1994. Dyspnea was not progressive. There was no history of cough, fever, chest pain, or palpitation. He was i...

Cardioprotective role of wedelolactone in restraint stress-triggered myocardial damage and cardiac arrhythmias in Wistar rats.

Restraint stress is a well-established model for inducing psychological and physiological stress that triggers oxidative damage, inflammation, and apoptosis in cardiac tissue. Wedelolactone, a bioacti...

Assessment of Coronary Sinus Flow and Dimensions by Transthoracic Echocardiography in Patients with Atrioventricular Nodal Reentrant Tachycardia.

BACKGROUND: The coronary sinus (CS) plays a pivotal role in cardiac venous drainage and is anatomically adjacent to the atrioventricular nodal region. Although structural enlargement of the CS has bee...

Alteration of the aortic wall structure and biomechanics in the sealing zone after EVAR: insights from an experimental study.

BACKGROUND: Endovascular repair has become state of the art for treating thoracic and abdominal aortic aneurysms. However, complications such as endoleaks or the development of aortic neck dilatation,...

[Development, morphogenesis, and regeneration of cardiac Purkinje fibers].

Ventricular arrhythmias often originate in the Purkinje system, a network of specialized cardiomyocytes located on the luminal surface of the ventricles. The Purkinje system is part of the ventricular...

Perioperative safety and short-term survival outcomes of radical nephrectomy with thrombectomy in geriatric renal cell carcinoma patients with venous tumor thrombus.

BACKGROUND: The aim of this study was to evaluate the feasibility and safety of radical nephrectomy with thrombectomy for geriatric renal cell carcinoma (RCC) patients with venous tumor thrombus (VTT)...

[Research advances in mechanisms and detection methods of vascular endothelial barrier dysfunction in sepsis-induced organ injury].

Sepsis-induced multiple organ dysfunction syndrome (MODS) is the leading cause of mortality in critically ill patients, and widespread disruption of the vascular endothelial barrier represents the cen...

Electrical coupling between transplanted cardiomyocytes and host myocardium to prevent arrhythmia.

Transplantation of human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes offers new opportunities for myocardial repair after infarction. However, as demonstrated in large-animal model st...

The determination of the heart size in 100 clinically thorax-disease-free pet rabbits (Oryctolagus cuniculus forma domestica) using the Vertebral Heart Score (VHS).

OBJECTIVE: To establish reference values for the Vertebral Heart Score (VHS) in pet rabbits that are clinically free of thorax disease. MATERIALS AND METHODS: Radiographs of 100 pet rabbits without cl...

Prognostic value of preoperative peak atrial longitudinal strain for patients undergoing mitral valve surgery.

AIMS: In asymptomatic severe degenerative mitral regurgitation (MR), indications for surgery mainly rely on 2D echocardiographic criteria. Preoperative peak atrial longitudinal strain (PALS) has progn...

A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss.

A growing body of research suggests a link between immune system activation and the development of Parkinson's disease (PD). Previous work showed that repeated gastrointestinal infection with Citrobac...

Automated Deep Learning Quantification of Avascular Area and Intravitreal Neovascularization in Retinal Flatmounts of Rodent Oxygen-Induced Retinopathy Models.

PURPOSE: To develop a single deep learning model that quantifies the retinal avascular area (AVA) and intravitreal neovascularization (IVNV) in rodent oxygen-induced retinopathy (OIR) models. METHODS:...