Barium-associated intestinal ischemia complicated with massive hepatic portal venous gas: A successful survival case report.
Barium-associated intestinal ischemia is a rare but life-threatening complication following upper gastrointestinal barium contrast examinations, with an incidence of less than 0.01%. Hepatic portal ve...
Does New Rapid Optical Coherence Tomography Angiography Acquisition Affect Image Quality in Healthy and Diseased Eyes?
PURPOSE: The purpose of this study was to compare standard 85 kilohertz (kHz) and newer high-speed 125 kHz optical coherence tomography angiography (OCTA) scanning modes in healthy and diseased eyes, ...
Age-related arterial stiffness and cerebrovascular dysfunction in mice correlate with cognitive impairment but are not reduced with long-term ALT-711 treatment.
Age-related increases in large artery stiffness contribute to cerebrovascular dysfunction and cognitive impairment. Alagebrium Chloride (ALT-711) is a collagen crosslink breaker that reduces vascular ...
Qualitative and Quantitative Assessment of Restored Capillary Perfusion on OCT Angiography in Diabetic Macular Ischemia.
PURPOSE: The purpose of this study was to investigate characteristics of restored capillary perfusion on optical coherence tomography angiography (OCTA) in diabetic retinopathy (DR). METHODS: We prosp...
Saikosaponin D Alleviates Atherosclerosis by Regulating Autophagy and Senescence of VSMCs via Inhibiting EPHB2.
BACKGROUND: Atherosclerosis (AS) is a major cause of cardiovascular diseases, with OX-LDL-induced VSMC dysfunction being a critical pathogenic driver of AS development. Saikosaponin D (SSD), a bioacti...
Selective titin cleavage disrupts cardiac mechanical homeostasis to drive heart failure and fibrosis.
Titin, the largest human protein, forms the elastic sarcomeric backbone, providing passive stiffness and length-dependent activation in cardiomyocytes. Whereas titin mutations cause inherited cardiomy...
Next-generation intranasal delivery nano-platforms for targeted brain therapy of Alzheimer's disease.
INTRODUCTION: Alzheimer's disease (AD) is a progressive neurodegenerative disorder that poses a growing global health burden. Effective drug delivery to the brain is largely constrained by the selecti...
Biventricular Coupling: Physiological Function, Anatomical Remodeling and Advances in Ultrasound Imaging.
The cardiovascular system is among the earliest functional systems in fetal development, playing a central role in maintaining circulation and ensuring oxygen and nutrient delivery. The fetal heart un...
The illusory correlation between geometrical similarity and physician satisfaction in heart auto-segmentation revealed by a physician-blind test.
BACKGROUND: Auto-segmentation tools are essential in adaptive radiation therapy (ART). While evaluation typically relies on geometric metrics like Dice similarity coefficient (DSC), high scores do not...
Long-term prognostic impact of optical coherence tomography detected plaque rupture in nonculprit coronary segments.
BACKGROUND AND AIMS: Atherosclerotic plaque rupture is largely acknowledged as the main mechanism of acute coronary syndrome. However, the prognostic significance of plaque rupture detected in nonculp...
Exercise as medicine: Improving cardiovascular health through physical activity.
Cardiovascular diseases remain the leading cause of global mortality, and growing evidence shows that regular exercise is one of the most effective non-pharmacological strategies to prevent and modify...
Early Outcomes of Real-World Aortic Valve Replacement With RESILIA Tissue in the Chinese Population.
BACKGROUND: Aortic valve replacement (AVR) with the INSPIRIS RESILIA aortic valve (Edwards Lifesciences, Irvine, CA) has established durability and promising outcomes. However, real-world safety and f...
Association Between Carotid Arterial Strain and Heart Rate Variability in Older Age.
Loss of the normal heart rate variability (HRV) predicts death. This study investigated the association between carotid arterial strain (CAS) and HRV in an older age population-based cohort. We hypoth...
Left Atrial Strain in Heart Failure With Reduced Ejection Fraction (HFrEF) and Angiotensin Receptor-Neprilysin Inhibition: The CLEAR Study.
BACKGROUND: Sacubitril-valsartan (SV), an angiotensin receptor-neprilysin inhibitor, improves clinical outcomes in HFrEF patients through reverse remodeling; however, predictors of response remain unc...
Integrated Blood Inflammatory Ratios and Cerebrospinal Fluid Blood‒Brain Barrier Dysfunction Predict Relapse Risk in Neuromyelitis Optica Spectrum Disorder.
BACKGROUND: Relapse is the primary driver of irreversible disability accumulation in neuromyelitis optica spectrum disorder (NMOSD). Although aquaporin-4 immunoglobulin G (AQP4-IgG) is central to dise...
Single-port extraperitoneal right hemicolectomy with complete mesocolic -A human cadaveric study.
BACKGROUND: Extraperitoneal access strategies have been successfully applied to left-sided colorectal resections, but their application to right-sided colectomy with complete mesocolic excision (CME) ...
The Tricuspid Valve in Patients With Transposition of the Great Arteries and a Systemic Right Ventricle: Morphological and Pathophysiological Insights From Three-Dimensional Echocardiography.
AIMS: Tricuspid regurgitation (TR) is related to heart failure (HF) progression in individuals with transposition of the great arteries (TGA) and a systemic right ventricle (sRV). While tricuspid valv...
Identifying the interaction between skin temperature, maintained thermal comfort, and conduit artery shear rate through limb passive heating.
Cardiovascular disease remains the leading cause of mortality. One reason is vascular dysfunction leading to pathological shear rate pattern. Limb passive heating (LPH) is a non-pharmacological interv...
Correlation of Noninvasive Assessment of Left Ventricular End Diastolic Pressure Using Tissue Doppler and Left Atrial Speckle Tracking Echocardiography with Invasive Measurements in Heart Failure Patients.
PURPOSE: Assessing left ventricular end diastolic pressure (LVEDP) is critical in managing patients with heart failure. This study aims to explore the utility of left atrial speckle tracking echo (STE...
Correlation Analysis Between Tomographic, Biomechanical, and Chorioretinal Changes in Patients With Keratoconus.
PURPOSE: To evaluate chorioretinal vascular changes in patients with keratoconus using optical coherence tomography angiography. METHODS: This mixed retrospective-prospective clinical study was conduc...