Effects of sodium-glucose cotransporter 2 inhibitors on cardiovascular outcomes in chronic obstructive pulmonary disease: A systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials.
ObjectiveSodium-glucose cotransporter 2 inhibitors are widely used in the management of diabetes mellitus and have demonstrated substantial cardiovascular and renal protective effects, particularly in...
[Clinical application value of sST2 in patients with heart failure].
OBJECTIVES: Accurate diagnosis and prognostic assessment of heart failure are crucial for improving patients' quality of life. This study aims to investigate the clinical value of serum soluble growth...
Systematic Review: Mineralocorticoid Receptor Antagonists in Heart Failure with Preserved and Mildly Reduced Ejection Fraction.
Heart failure with preserved ejection fraction (HFpEF) or mildly reduced ejection fraction (HFmrEF) is a prevalent condition associated with significant morbidity and mortality, and the benefits of mi...
通过GDP-状态稳定抑制RhoA激活以缓解心力衰竭。
Given the persistently high morbidity and mortality of heart failure (HF), targeting myocardial remodeling, particularly pathological hypertrophy and fibrosis, has become a major therapeutic priority....
血管紧张素Ⅱ诱导的心脏病中的磷酸肌醇耗竭和代偿性磷酸信号传导：通过PTEN抑制进行保护。
Contractile dysfunction, hypertrophy, and cell death during heart failure are linked to altered Ca Mice received 1-week infusions of AngII, bisperoxovanadium 1,10 phenanthroline, both, or saline via o...
急性心力衰竭期间的胰腺受累：来自AVANTI试验的见解。
暂无摘要
变异3-9同源物1缺乏的抑制因子通过TACC2减轻心脏纤维化并挽救心力衰竭。
Aberrant and excessive cardiac fibrosis contributes to heart failure. Resident cardiac fibroblasts are the primary source of myofibroblasts that produce extracellular matrix proteins to mediate cardia...
From Bridge to Destination: How Next-Generation Ventricular Assist Devices are Redefining End-Stage Heart Failure.
Next-generation LVADs transform heart failure care from transplant bridge to destination therapy.
Sleep Disorder Phenotypes and the Risk of Incident Heart Failure: A meta-analysis with Mendelian randomization validation.
OBJECTIVES: To quantify how specific sleep-disorder phenotypes are related to incident heart failure (HF) using a meta-analysis of cohort data and to probe causal relevance via 2-sample Mendelian rand...
Correlates of serum thiamine levels among acute decompensated heart failure patients.
BACKGROUND: Acute decompensated heart failure (ADHF) contributes adversely to health-related outcomes. Anorexia, early satiety, high metabolic rates, malnutrition, advanced age, and diuretic use chara...
终末期肾病、主要心血管事件和死亡与全身炎症的关系
全身炎症可能在慢性肾病的进展和主要心血管事件（MACE）的发展中发挥作用，但这种效应是否独立于传统心血管危险因素尚不清楚。本研究评估了炎症标志物与终末期肾病（ESKD）患者主要心血管事件和死亡之间的关系。研究纳入了接受透析治疗的ESKD患者，测量了多种炎症标志物（包括C反应蛋白、白细胞介素-6等），并进行了长期随访。主要终点为主要心血管事件（定义为心血管死亡、非致死性心肌梗死和非致死性卒中的复合终...
Multilevel functional quantile principal component analysis.
Accelerometer studies typically include repeated 24-h observations over several days and more recently have collected information on participants for weeks, months, or years. Meanwhile, there is growi...
Exploring the palliative care needs of patients with heart failure: A qualitative study.
BACKGROUND: Despite the increasing recognition of palliative care in the management of heart failure (HF), many patients continue to experience unmet care needs due to the delayed integration of suppo...
Mortality and cardiovascular risk of triglyceride-glucose and derived indices in cardiovascular-kidney-metabolic syndrome stages 0-3: a dose-response meta-analysis.
BACKGROUND: The associations of the triglyceride-glucose (TyG) index and its derived indices with the progression of cardiovascular-kidney-metabolic (CKM) syndrome remain poorly elucidated. METHODS: W...
Bidirectional impact between cardiovascular comorbidities and heart failure: an updated position paper from the Italian society of cardiology (SIC) working group on heart failure.
Heart failure (HF) and cardiovascular (CV) diseases (CVD) are closely interconnected through a complex and bidirectional relationship. HF frequently represents the final common pathway of several CV c...
Frailty and nutritional status as prognostic factors in older adults with heart failure: a public health perspective.
BACKGROUND: Heart failure is a common cardiovascular disease among older adults. Combined with frailty, it may aggravate the patient's condition and affect the prognosis. Nutritional status is importa...
Prevalence and associated factors of cognitive frailty in older adults with heart failure: a systematic review and meta-analysis.
OBJECTIVES: To explore the prevalence and associated factors of cognitive frailty in older adults with heart failure. DESIGN: A systematic review and meta-analysis. METHODS: We systematically searched...
Non-lean versus lean MASLD: associations with advanced cardiovascular-kidney-metabolic syndrome in adults with type 2 diabetes mellitus, a cross-sectional study.
INTRODUCTION: This study seeks to explore the impact of lean and non-lean phenotypes of metabolic dysfunction-associated steatotic liver disease (MASLD) on the prevalence of advanced cardiovascular-ki...
Behavioral and health-factor domains of Life's Essential 8 in advanced cardiovascular-kidney-metabolic syndrome among Korean adults: a nationally representative cross-sectional analysis.
INTRODUCTION: Life's Essential 8 (LE8) summarizes cardiovascular health through four behavioral and four health-factor metrics, whereas cardiovascular-kidney-metabolic (CKM) syndrome staging character...
A clinical prediction model integrating cardiovascular-kidney-metabolic biomarkers for the composite outcome of quality-of-life deterioration and rehospitalization in elderly HFpEF patients.
BACKGROUND: Cardiovascular-kidney-metabolic (CKM) syndrome stage 4a encompasses elderly heart failure with preserved ejection fraction (HFpEF) patients with metabolic risk factors or chronic kidney di...