Triglyceride-glucose index as a predictor of adverse cardiovascular outcomes in a contemporary, diverse US population undergoing percutaneous coronary intervention.
BACKGROUND AND AIMS: The triglyceride-glucose (TyG) index has emerged as a powerful and accessible marker of insulin resistance and a predictor of adverse events in patients undergoing percutaneous co...
Coronary Artery Disease Prediction in Korean Patients with Familial Hypercholesterolemia: Analysis Involving Cholesterol Efflux Capacity.
PURPOSE: Patients with familial hypercholesterolemia (FH) are at high risk of coronary artery disease (CAD), and its prediction is of great clinical importance. This study aimed to identify predictors...
High-Intensity Statin Treatment Is Associated With Reduced Growth Differentiation Factor-15 in Patients With Coronary Artery Disease.
BACKGROUND: Growth differentiation factor-15 (GDF-15) is upregulated in coronary artery disease (CAD). The relationship of intensive statin therapy with circulating GDF-15 levels has not been explored...
Effect and Clinical Characteristics of Human Cytomegalovirus Infection on Vascular Inflammation in Patients With Coronary Atherosclerotic Heart Disease.
This study evaluated the impact of human cytomegalovirus (HCMV) infection on vascular inflammation and clinical characteristics in patients with coronary atherosclerotic heart disease (CHD). A total o...
Long-Term Follow-up After Percutaneous Coronary Interventions for Chronic Total Occlusions.
BACKGROUND: Percutaneous coronary interventions (PCI) for chronic total occlusions (CTO) remain challenging procedures with controversial long-term clinical benefits. METHODS: We conducted an observat...
Colchicine in coronary heart disease: from inflammatory biology to secondary prevention.
Inflammation is now recognised as a central mechanism in atherosclerosis and its clinical complications, shifting coronary heart disease management beyond exclusive lipid lowering and antithrombotic t...
Colchicine in coronary artery disease: limitations and challenges.
Colchicine has emerged as a promising anti-inflammatory option for secondary prevention in coronary artery disease, but its role in routine practice remains uncertain. Evidence from randomised trials ...
Velocimetry based on multiphase CCTA images for reliable coronary flow velocity quantification across stenosis severities and ischemia detection.
BACKGROUND: Coronary flow velocity (CFV) serves as a critical functional feature for evaluating coronary stenosis severity (CSS) and detecting ischemia. With its noninvasive nature and rapid imaging, ...
Machine Learning With Genetic and Clinical Data to Predict Ischemic Outcomes After PCI.
Ischemic events after contemporary percutaneous coronary intervention (PCI) are uncommon but carry high morbidity/mortality. Identifying patients at highest risk is critical to guide dual antiplatelet...
Visit-to-Visit Systolic Blood Pressure Variability Predicts Long-Term Cardiovascular Events After Coronary Artery Bypass Grafting.
This prospective observational study investigated whether systolic blood pressure variability (SBPV) during the transitional care period predicts long-term outcomes after coronary artery bypass grafti...
CAD-RADS 2.0 - Update on the evaluation and management of coronary artery disease with coronary CT angiography.
The updated Coronary Artery Disease Reporting and Data System (CAD-RADS 2.0) adds new features for patients undergoing coronary CT angiography (CCTA). The following features are included in the new sy...
High postprandial endotoxemia is associated with recurrence of cardiovascular events in patients with coronary heart disease: from the CORDIOPREV randomized clinical trial.
BACKGROUND: The translocation into the systemic circulation of proinflammatory bacterial components such as lipopolysaccharide (LPS) has been linked to cardiovascular disease (CVD). OBJECTIVES: We aim...
Characteristics of non-culprit coronary artery lesions assessed by intravascular ultrasound in patients with ST-segment elevation myocardical infarction.
BACKGROUND: Non-culprit coronary lesions are increasingly recognized as an important source of recurrent cardiovascular events in patients with ST-segment elevation myocardial infarction (STEMI). Intr...
A 12-week Exercise Intervention Among Older Adults With Chronic Coronary Syndrome: Changes and Associations of Movement Behaviors and Cardiovascular Risk Factors.
Physical activity (PA) is key to improve the prognosis of patients with chronic coronary syndrome (CCS). This study investigated changes in movement behaviors (MB), obesity markers, cardiorespiratory ...
Role of Personalized Medicine in Myocardial Infarction With Nonobstructive Coronary Artery Disease (MINOCA): An Updated Review.
Cardiovascular diseases, notably myocardial infarction (MI), contribute significantly to global mortality. While traditional MIs are often associated with notable coronary artery blockages, a subgroup...
Association of SCARB1 Polymorphisms with Coronary Artery Disease Risk: A Systematic Review and Meta-Analysis.
BACKGROUND: Coronary artery disease (CAD) remains a major cause of morbidity and mortality worldwide. Variants in the lipid metabolism gene SCARB1 may influence CAD susceptibility, but existing eviden...
Immunothrombotic Cell-Cell Communication Networks in Coronary Atherosclerosis: Critical Insights from Single-Cell and Spatial Systems Biology.
Coronary artery disease (CAD) is increasingly recognized as a thromboinflammatory disorder in which innate immune activation and coagulation are tightly coupled within the plaque microenvironment. Eme...
Effect of home-based cardiac rehabilitation on quality of life, health behaviours and cardiac anxiety in patients with coronary artery disease: findings from a single-blinded randomised controlled trial.
OBJECTIVE: To evaluate the effectiveness of a contextually developed home-based cardiac rehabilitation (HBCR) programme on heart-related quality of life (QoL), cardiac health behaviours (CHB) and card...
Association between miRNAs and DEFA4 in coronary artery disease.
BACKGROUND: Coronary artery disease (CAD) is a leading cause of death worldwide, caused by environmental factors and characterized by the formation of atherosclerotic plaques. Identification of novel ...
AI-Based ECG Analysis for Early Detection of Occlusion Myocardial Infarction Using Coronary Angiography Results.
Myocardial Infarction remains a high-mortality cardiovascular disease. While ST-Elevation Myocardial Infarction (STEMI) is the traditional intervention standard, many Occlusion Myocardial Infarction (...