Triglyceride-glucose index level mediates the association between food inflammation index and advanced cardiovascular-kidney-metabolic syndrome: Evidence from NHANES 1999 to 2018.
The recent standardization of diagnostic criteria and phenotyping for cardiovascular-kidney-metabolic (CKM) syndrome has increased attention to this multisystem disorder which arises from the interact...
Survival and predictors of major adverse cardiovascular events among patients with acute coronary syndrome in Ethiopia: a retrospective cohort study.
OBJECTIVES: To determine the time to major adverse cardiovascular events (MACE) and identify its predictors among patients with acute coronary syndrome (ACS) discharged on secondary prevention medicat...
Tailored Text Messaging Intervention to Improve Self-Care in Patients With Heart Failure (Text4HF): Protocol for a Pilot Randomized Controlled Trial.
BACKGROUND: Heart failure (HF) is a major public health problem associated with frequent hospitalizations, high mortality, and substantial health care costs. Self-care is fundamental to improving heal...
Dyspnea in heart failure: pathophysiology, clinical assessment, and evidence from clinical trials.
Dyspnea is a key symptom of heart failure (HF), particularly in its acute form, where it represents the most common cause of hospitalization. Although traditionally attributed to pulmonary congestion,...
[A case of hereditary hemochromatosis with multi-organ involvement presenting primarily as heart failure].
遗传性血色病属于常染色体遗传性铁代谢异常疾病，发病核心机制为铁调素合成不足或功能缺陷，导致肠道铁吸收调控紊乱、机体铁负荷过载并在多器官过度沉积，引发相应脏器功能损害。该病起病隐匿，临床表现缺乏特异性，易被漏诊、误诊，多数患者常在进展至终末期器官并发症时才得以明确诊断。该文报道1例以心力衰竭为主要表现的2型遗传性血色病青年患者，旨在增强临床医师对该病的认知与识别能力，促进疾病早期诊断与系统性管理。.
Congestion-Perfusion Phenotypes and In-Hospital Mortality in Acute Heart Failure: Phenotype-Specific Prognostic Markers and Right-Heart Involvement.
Background and Objectives: Acute heart failure (AHF) has heterogeneous clinical profiles and considerable short-term mortality. Bedside evaluation of congestion and peripheral perfusion may help ident...
Feasibility of a noninvasive photoplethysmography-based wearable chest patch for cardiac output assessment during exercise compared with thermodilution right heart catheterization.
Hemodynamic monitoring with cardiac output (CO) assessment is usually based on invasive methods that are associated with potential complications. This study compared CO measurements during exercise ob...
The Future of Imaging in Heart Failure: Toward Precision Phenotyping, Integration, and Intelligence.
PURPOSE OF REVIEW: Heart failure (HF) is increasingly understood not as a single, uniformly treated diagnosis but as a heterogeneous syndrome requiring aetiological clarification, in which cardiac ima...
Exercise-Induced Plasma Surfactant Protein B Response in Advanced Heart Failure: Relation to Exercise Limitation, Resting Invasive Hemodynamics, and Clinical Outcomes.
Plasma surfactant protein B (SPB) is a marker of alveolar-capillary barrier injury and is elevated in heart failure (HF). We assessed whether cardiopulmonary exercise testing (CPET) changes plasma SPB...
Effects of Remote, Virtual, or Hybrid Cardiac Rehabilitation Supported by mHealth in Patients With Heart Failure: Systematic Review and Meta-Analysis.
BACKGROUND: Structured exercise is a key component of cardiac rehabilitation (CR) for patients with heart failure (HF), but access to center-based cardiac rehabilitation (CBCR) is often limited. Mobil...
Does Characterization of Phenotypic Heterogeneity Provide Mechanistic Insights or Influence the Response to Treatment? Experience in Positive and Neutral Trials in Patients With Heart Failure and a Preserved Ejection Fraction.
At a time when there was no unifying hypothesis and no broadly effective treatments for heart failure with a preserved ejection fraction (HFpEF), it was proposed that HFpEF represented a multitude of ...
[Lonicera japonica attenuates oxidative stress and improves post-ischemic heart failure in mice via the STAT3/PGC-1α axis].
OBJECTIVES: To investigate the mechanism by which freeze-dried water extract of Lonicera japonica alleviates oxidative stress and improves post-ischemic heart failure in mice. METHODS: Bioinformatics ...
Predictive value of the serum sodium to log(D-dimer) ratio for the risk of all-cause death in patients with chronic heart failure with different ejection fractions.
BACKGROUND: The ratio of serum sodium to log(D-dimer) (log-SDR) in different types of chronic heart failure (CHF) is not well established. METHODS: A total of 1,221 hospitalized CHF patients from the ...
Prognostic Impact of Baseline Potassium Abnormalities in Patients with Heart Failure with Reduced Ejection Fraction: A Real-World Cohort Study.
INTRODUCTION: Abnormal serum potassium levels are a common issue in patients with heart failure with reduced ejection fraction (HFrEF), limiting the use of prognostically beneficial therapies. The pri...
Risk factors associated with malnutrition in elderly patients with chronic heart failure.
This retrospective observational study aimed to identify clinical determinants of malnutrition in elderly patients with chronic heart failure. Elderly patients (≥65 years) with established chronic hea...
GLP-1 Receptor Agonists: From Clinical Success to Mechanistic Insight.
GLP-1R (glucagon-like peptide-1 receptor) agonists are transforming therapeutic strategies in hypertension and cardiometabolic syndrome by shifting the focus from merely controlling individual risk fa...
Social Deprivation Index Is Associated with 90-Day Emergency Department Revisits, but Not Admission, for Acute Heart Failure.
BACKGROUND: Prevalence of heart failure is increasing, with an associated rise in emergency department (ED)-related care. Social determinants of health (SDoH) are associated with adverse health outcom...
Point-of-care Ultrasound for Detecting Methamphetamine-associated Heart Failure in the Emergency Department.
INTRODUCTION: Methamphetamine-associated heart failure with reduced ejection fraction is a serious consequence of methamphetamine use often underrecognized in the emergency department (ED). Point-of-c...
Differentiating HFmr/rEF from HFpEF using standard 12-lead ECG measurements: an interpretable machine learning study.
BACKGROUND: Differentiating heart failure (HF) with mildly reduced/reduced ejection fraction (HFmr/rEF) from HF with preserved ejection fraction (HFpEF) guides therapy but echocardiography may be dela...
Excess risk for cardiovascular and noncardiovascular comorbidities and multimorbidity among patients with myelodysplastic syndrome: A systematic review and meta-analysis.
The authors performed a systematic review and meta-analysis to estimate the prevalence of comorbidities among patients with myelodysplastic syndrome (MDS) by pooling results from 28 studies and 71,400...