Preoperative Risk Stratification of Cerebral Infarction in Aortic Arch Surgery Using Quantitative Atheroma Assessment with Computational Fluid Dynamics.

PURPOSE: We developed a quantitative method to evaluate aortic atheroma and investigated its association with postoperative cerebral infarction (CI) after aortic arch surgery. In addition, computation...

[Intracavitary thrombus as a differential diagnosis of intramyocardial dissection].

We present the case of a 47-year-old man with ischemic cardiomyopathy and a previous extensive acute myocardial infarction (AMI), who had undergone multiple percutaneous coronary interventions and pro...

Ventricular repolarization abnormalities in acute ischemic stroke.

INTRODUCTION: We evaluated the prevalence and clinical impact of ST-segment depression and/or T-wave inversion (ST-T changes) assessed on a standard electrocardiogram (ECG) among patients with an acut...

[Atrioventricular block after percutaneous closure of an ostium secundum-type atrial septal defect with Nit-Occlud devices].

INTRODUCTION: Percutaneous treatment is currently the method of choice for ostium secundum atrial septal defects (OS-ASD) treatment. However, this procedure may be associated with an increased inciden...

[Acute myocardial infarction complicated by interventricular septal rupture and left ventricular thrombus].

We present the case of a 76-year-old woman, with a history of smoking and dyslipidemia, who was admitted with acute heart failure associated with a holosystolic murmur. The electrocardiogram showed an...

Prevalence and determinants of poor outcome in patients with chronic kidney disease in low-income countries in sub-Saharan Africa: a systematic review.

Chronic kidney disease (CKD) is a significant health burden globally, associated with high healthcare costs and mortality rates. In Africa, the prevalence of CKD is estimated at around 10-15% in adult...

Barrier-to-Design Codes for Organ-Targeted Nanomedicine: A Framework Linking Barrier Phenotypes to Nano-Bio Interface Design and Translational Validation.

Organ-targeted nanomedicine is often defined by anatomical destination, yet delivery performance is determined by the biological barriers, disease-associated remodeling, and nano-bio interface interac...

Subclinical primary aldosteronism: toward a conceptual framework linking primary aldosteronism and low-renin hypertension.

Primary aldosteronism (PA) has traditionally been considered a rare cause of secondary hypertension, but growing evidence supports a broader continuum of renin-independent aldosterone production exten...

Association of Composite Metabolic Indices and Oxidative Stress Biomarkers with Coronary Atherosclerosis Detected by CT Angiography in Premenopausal Women with Metabolic Syndrome.

BACKGROUND: Metabolic syndrome (MetS) is increasingly prevalent among premenopausal women and is associated with a higher risk of subclinical atherosclerosis. This study investigated whether composite...

Association of C-reactive protein-albumin-lymphocyte index and coronary artery calcification on major adverse cardiovascular events of dialysis patients with acute coronary syndrome.

BACKGROUND AND OBJECTIVE: Inflammation, immune dysfunction, malnutrition and severe coronary artery calcification (CAC) are critical cardiovascular risk factors in patients on dialysis. However, their...

Development and Evaluation of a Clinical Prediction Model for Acute Kidney Injury Risk in Elderly Patients with Heart Failure with Reduced Ejection Fraction.

BACKGROUND: Acute kidney injury (AKI) is a significant complication among patients with heart failure with reduced ejection fraction (HFrEF). Once AKI occurs, therapeutic options are limited to suppor...

Analysis of macular and optic nerve vasculature using optical coherence tomography angiography in patients with human T-cell lymphotropic virus type 1.

PURPOSE: To compare macular and optic nerve head (ONH) microvasculature using optical coherence tomography angiography (OCT-A) in asymptomatic human T-cell lymphotropic virus type 1 (HTLV-1) carriers ...

Carotid intraplaque neovascularization and cerebral microbleeds: correlation assessed by plane-wave ultrasensitive flow imaging.

OBJECTIVE: Carotid intraplaque neovascularization (IPN) is a marker of plaque vulnerability, whereas cerebral microbleeds (CMBs) are established markers of cerebral small vessel disease. However, the ...

Endocrine regulation of cardiac fibrosis: implications for HFpEF.

Heart failure with preserved ejection fraction (HFpEF) is a dominant heart failure phenotype in ageing populations and commonly develops on a background of hypertension, obesity, diabetes, and systemi...

A scoring system for predicting the difficulty of trans-radial cerebral angiography.

BACKGROUND: Despite the growing adoption of trans-radial access in neurointervention, no validated scoring system currently exists to predict procedural difficulty of trans-radial cerebral angiography...

Thyroid hormone sensitivity, insulin resistance and visceral fat area as determinants of prevalent coronary heart disease in euthyroid patients with type 2 diabetes.

BACKGROUND: Coronary heart disease (CHD) remains a leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Whether thyroid hormone sensitivity indices add value for ...

Predictors of Illness Acceptance Among Hypertensive Patients in Freetown: A Multivariate Analysis of Sociodemographic, Religiosity, and Quality of Life Factors.

ObjectivesTo determine the sociodemographic, religiosity, and quality of life (QoL) predictors of illness acceptance among hypertensive patients.MethodsThis cross-sectional study included 317 patients...

Association between gallstones and subclinical coronary atherosclerosis: An observational study with propensity score matching.

Previous studies reporting an association between gallstones and coronary artery disease have not considered the types of coronary artery plaque. Additionally, the association between gallstones and s...

Dielectrophoretic estimation of resting membrane potential in excitable cells.

The cell membrane potential (Vm) is of paramount significance in cell electrophysiology, most notably in excitable cells found in muscle and nervous tissues. Vm is the voltage between the cell interio...

Migraine with visual aura, unilateral mydriasis and Takotsubo Syndrome. Random coincidence or common pathogenesis? The precarious balance of the autonomic nervous system and the complex relationship between brain and heart: a review of the literature.

OBJECTIVE: The recent examination of a woman who presented a migraine attack with visual aura and unilateral mydriasis, followed, a few days later, by an episode of Takotsubo Syndrome, prompted us to ...